Results 21 to 30 of about 10,893 (158)

High frequency of enterotoxigenic Bacteroides fragilis and Enterococcus faecalis in the paraffin-embedded tissues of Iranian colorectal cancer patients. [PDF]

BMC Cancer, 2021
The association between specific bacteria and colorectal cancer (CRC) has been proposed. Only a few studies have, however, investigated this relationship directly in colorectal tissue with conflicting results.
Khodaverdi N, Zeighami H, Jalilvand A, Haghi F, Hesami N.   +4 more
europepmc   +2 more sources

Microbiota enterotoxigenic Bacteroides fragilis-secreted BFT-1 promotes breast cancer cell stemness and chemoresistance through its functional receptor NOD1. [PDF]

Protein Cell
Tumor-resident microbiota in breast cancer promotes cancer initiation and malignant progression. However, targeting microbiota to improve the effects of breast cancer therapy has not been investigated in detail.
Ma W, Zhang L, Chen W, Chang Z, Tu J, Qin Y, Yao Y, Dong M, Ding J, Li S, Li F, Deng Q, Yang Y, Feng T, Zhang F, Shao X, He X, Zhang L, Hu G, Liu Q, Jiang YZ, Zhu S, Xiao Z, Su D, Liu T, Liu S.   +25 more
europepmc   +2 more sources

Detection of Streptococcus gallolyticus and Four Other CRC-Associated Bacteria in Patient Stools Reveals a Potential "Driver" Role for Enterotoxigenic Bacteroides fragilis. [PDF]

Front Cell Infect Microbiol, 2022
Purpose Streptococcus gallolyticus subspecies gallolyticus (SGG) is an opportunistic pathogen causing invasive infections in the elderly often associated with colon neoplasia.
Périchon B, Lichtl-Häfele J, Bergsten E, Delage V, Trieu-Cuot P, Sansonetti P, Sobhani I, Dramsi S.   +7 more
europepmc   +2 more sources

LRP11-AS1 mediates enterotoxigenic Bacteroides fragilis-related carcinogenesis in colorectal Cancer via the miR-149-3p/CDK4 pathway. [PDF]

Cancer Gene Ther
Long noncoding RNAs (lncRNAs) are critical in tumorigenesis and show potential for tumor diagnosis and therapy. Enterotoxigenic Bacteroides fragilis (ETBF), known for producing enterotoxins, is implicated in human gut tumorigenesis, yet the underlying ...
Wu Z, Yu M, Zeng Y, Huang Y, Zheng W.
europepmc   +2 more sources

Association of Enterotoxigenic <i>Bacteroides fragilis</i> with Immune Modulation in Colorectal Cancer Liver Metastasis. [PDF]

Cancers (Basel)
Simple Summary Bacteria living inside tumors can shape how cancers grow. We examined one such microbe, enterotoxigenic Bacteroides fragilis (ETBF), in liver metastases removed from 226 patients with colorectal cancer. A highly sensitive DNA test detected
Saito R, Shigematsu Y, Amori M, Amori G, Takamatsu M, Nishida K, Kanda H, Takahashi Y, Miura Y, Takeuchi K, Takahashi S, Inamura K.   +11 more
europepmc   +2 more sources

Intratumoral presence of the genotoxic gut bacteria pks⁺ E. coli, Enterotoxigenic Bacteroides fragilis, and Fusobacterium nucleatum and their association with clinicopathological and molecular features of colorectal cancer. [PDF]

Br J Cancer
This study aimed to investigate clinicopathological and molecular tumour features associated with intratumoral pks+Escherichia coli (pks+E.coli+), pks+E.coli- (non-E.coli bacteria harbouring the pks island), Enterotoxigenic Bacteroides fragilis (ETBF ...
Joo JE, Chu YL, Georgeson P, Walker R, Mahmood K, Clendenning M, Meyers AL, Como J, Joseland S, Preston SG, Diepenhorst N, Toner J, Ingle DJ, Sherry NL, Metz A, Lynch BM, Milne RL, Southey MC, Hopper JL, Win AK, Macrae FA, Winship IM, Rosty C, Jenkins MA, Buchanan DD.   +24 more
europepmc   +2 more sources

Repositioning small molecule drugs as allosteric inhibitors of the BFT-3 toxin from enterotoxigenic Bacteroides fragilis. [PDF]

Protein Sci, 2022
Bacteroides fragilis is an abundant commensal component of the healthy human colon. However, under dysbiotic conditions, enterotoxigenic B. fragilis (ETBF) may arise and elicit diarrhea, anaerobic bacteremia, inflammatory bowel disease, and colorectal ...
Jimenez-Alesanco A, Eckhard U, Asencio Del Rio M, Vega S, Guevara T, Velazquez-Campoy A, Gomis-Rüth FX, Abian O.   +7 more
europepmc   +2 more sources

Risk Factors for Enterotoxigenic Bacteroides fragilis Infection and Association with Environmental Enteric Dysfunction and Linear Growth in Children: Results from the MAL-ED Study. [PDF]

Am J Trop Med Hyg, 2022
. Despite reports of enterotoxigenic Bacteroides fragilis (ETBF) isolation from asymptomatic children, no reports exist regarding the possible association of ETBF with long-term complications such as development of environmental enteric dysfunction (EED)
Palit P, Das R, Haque MA, Nuzhat S, Khan SS, Siddiqua TJ, Mahfuz M, Faruque ASG, Ahmed T.   +8 more
europepmc   +2 more sources

In Vitro Evaluation of the Therapeutic Potential of Phage VA7 against Enterotoxigenic Bacteroides fragilis Infection [PDF]

Viruses, 2021
Since the beginning of the 20th century, bacteriophages (phages), i.e., viruses that infect bacteria, have been used as antimicrobial agents for treating various infections. Phage preparations targeting a number of bacterial pathogens are still in use in
Nata Bakuradze, Maya Merabishvili, Khatuna Makalatia, Elene Kakabadze, Nino Grdzelishvili, Jeroen Wagemans, Cedric Lood, Irakli Chachua, Mario Vaneechoutte, Rob Lavigne, Jean-Paul Pirnay, Ivane Abiatari, Nina Chanishvili   +12 more
doaj   +2 more sources

Enterotoxigenic and nontoxigenic Bacteroides fragilis strains isolated in Brazil [PDF]

Memorias do Instituto Oswaldo Cruz, 2008
The presence of enterotoxigenic Bacteroides fragilis and nontoxigenic B. fragilis (NTBF) among 109 strains isolated from 1980-2008 in Brazil were investigated by PCR.
Karla R Miranda, Mariana F Dias, Priscilla LS Guimarães, Renata F Boente, Heidi Pauer, Priscila Z Ramos, Laís S Falcão, Eliane de O Ferreira, Ilana T Balassiano, Livia Q Ferreira, Joaquim dos Santos-Filho, Geraldo R de Paula, Eduardo NF Antunes, Katia ES Avelar, Regina MCP Domingues   +14 more
doaj   +4 more sources