Complete Genome Sequence of an Enterotoxigenic Bacteroides fragilis Clinical Isolate. [PDF]
ABSTRACT Here we present the complete genome sequence of Bacteroides fragilis isolate BOB25. It is an enterotoxigenic isolate that was obtained from a stool sample of a patient with dysbiosis.
Nikitina AS +10 more
europepmc +4 more sources
Stat3 Activation in Murine Colitis Induced by Enterotoxigenic Bacteroides fragilis [PDF]
Enterotoxigenic Bacteroides fragilis (ETBF), a molecular subclass of the common human commensal, B. fragilis, has been associated with inflammatory bowel disease. ETBF colitis is characterized by the activation of Stat3 and a Th17 immune response in the colonic mucosa.
Wick, Elizabeth +11 more
openaire +4 more sources
In Vitro Evaluation of Propolis Effects on Bacteroides fragilis Toxin-mediated Inflammatory Pathways
Colorectal cancer (CRC) remains a significant global health concern because of its increasing incidence and mortality rates. Chronic intestinal inflammation is a critical driver in the pathogenesis of CRC, particularly in individuals with inflammatory ...
Soonjae HWANG, Yeram LEE, Ki-Jong RHEE
doaj +1 more source
Diarrheal disease caused by enterotoxigenic Bacteroides fragilis in infant rabbits [PDF]
Enterotoxigenic Bacteroides fragilis caused severe, nonhemorrhagic, watery diarrhea when 10(9) CFU of a porcine or human isolate was administered orogastrically to 3-day-old rabbits. The bacterium colonized the intestinal tract with a predilection for the large intestine (10(9) CFU/g of cecal contents).
L L, Myers +3 more
openaire +2 more sources
Effect of gut microbiota in the colorectal cancer and potential target therapy
The symbiotic interaction between gut microbiota and the digestive tract is an important factor in maintaining the intestinal environment balance. Colorectal cancer (CRC) is a complex disease involving the interaction between tumour cells and a large ...
Junchuan Li +3 more
doaj +1 more source
Intestinal bacteria and colorectal cancer: etiology and treatment
The etiology of colorectal cancer (CRC) is influenced by bacterial communities that colonize the gastrointestinal tract. These microorganisms derive essential nutrients from indigestible dietary or host-derived compounds and activate molecular signaling ...
Michael W. Dougherty, Christian Jobin
doaj +1 more source
The KeystoneâPathogen Hypothesis Updated: The Role of Porphyromonas gingivalis in Periodontitis
Porphyromonas gingivalis orchestrates a coordinated manipulation of immune and inflammatory responses in periodontal tissues which leads to the generation of a dysbiotic, subgingival biofilm community, and progression of periodontitis. The type 9 secretion system, lipid A modification, and the formation of outer membrane vesicles are important ...
Mike A. Curtis +2 more
wiley +1 more source
Association of EnterotoxigenicBacteroides fragilisInfection with Inflammatory Diarrhea [PDF]
Diarrheal illnesses remain a leading cause of morbidity and mortality globally, with increasing recognition of long-term sequelae, including postinfectious irritable bowel syndrome and growth faltering, as well as cognitive deficits in children. Identification of specific etiologic agents is often lacking.
Cynthia L, Sears +11 more
openaire +2 more sources
Abstract Colorectal cancer (CRC) and cardiovascular disease (CVD) are leading causes of morbidity and mortality worldwide, traditionally studied as distinct pathologies. However, emerging evidence suggests a significant physiological and molecular overlap between these conditions, indicating that they might share common pathophysiological pathways. The
Mohamad Bashir +5 more
wiley +1 more source
Monoclonal antibodies specific for Bacteroides fragilis enterotoxins BFT1 and BFT2 and their use in immunoassays. [PDF]
We have developed 22 mouse IgG1 monoclonal antibodies (mAbs) against Bacteroides fragilis zinc metalloprotease toxins 1 and 2 (BFT1 and BFT2). Mice were immunized with recombinant BFT1 or BFT2 proteins with metalloprotease activity.
Saraspadee Mootien, Paul M Kaplan
doaj +1 more source

