Results 61 to 70 of about 10,893 (158)

Complete Genome Sequence of an Enterotoxigenic Bacteroides fragilis Clinical Isolate. [PDF]

open access: yesGenome Announc, 2015
ABSTRACT Here we present the complete genome sequence of Bacteroides fragilis isolate BOB25. It is an enterotoxigenic isolate that was obtained from a stool sample of a patient with dysbiosis.
Nikitina AS   +10 more
europepmc   +4 more sources

Stat3 Activation in Murine Colitis Induced by Enterotoxigenic Bacteroides fragilis [PDF]

open access: yesInflammatory Bowel Diseases, 2014
Enterotoxigenic Bacteroides fragilis (ETBF), a molecular subclass of the common human commensal, B. fragilis, has been associated with inflammatory bowel disease. ETBF colitis is characterized by the activation of Stat3 and a Th17 immune response in the colonic mucosa.
Wick, Elizabeth   +11 more
openaire   +4 more sources

In Vitro Evaluation of Propolis Effects on Bacteroides fragilis Toxin-mediated Inflammatory Pathways

open access: yesKorean Journal of Clinical Laboratory Science
Colorectal cancer (CRC) remains a significant global health concern because of its increasing incidence and mortality rates. Chronic intestinal inflammation is a critical driver in the pathogenesis of CRC, particularly in individuals with inflammatory ...
Soonjae HWANG, Yeram LEE, Ki-Jong RHEE
doaj   +1 more source

Diarrheal disease caused by enterotoxigenic Bacteroides fragilis in infant rabbits [PDF]

open access: yesJournal of Clinical Microbiology, 1989
Enterotoxigenic Bacteroides fragilis caused severe, nonhemorrhagic, watery diarrhea when 10(9) CFU of a porcine or human isolate was administered orogastrically to 3-day-old rabbits. The bacterium colonized the intestinal tract with a predilection for the large intestine (10(9) CFU/g of cecal contents).
L L, Myers   +3 more
openaire   +2 more sources

Effect of gut microbiota in the colorectal cancer and potential target therapy

open access: yesDiscover Oncology, 2022
The symbiotic interaction between gut microbiota and the digestive tract is an important factor in maintaining the intestinal environment balance. Colorectal cancer (CRC) is a complex disease involving the interaction between tumour cells and a large ...
Junchuan Li   +3 more
doaj   +1 more source

Intestinal bacteria and colorectal cancer: etiology and treatment

open access: yesGut Microbes, 2023
The etiology of colorectal cancer (CRC) is influenced by bacterial communities that colonize the gastrointestinal tract. These microorganisms derive essential nutrients from indigestible dietary or host-derived compounds and activate molecular signaling ...
Michael W. Dougherty, Christian Jobin
doaj   +1 more source

The Keystone‐Pathogen Hypothesis Updated: The Role of Porphyromonas gingivalis in Periodontitis

open access: yesJournal of Periodontal Research, EarlyView.
Porphyromonas gingivalis orchestrates a coordinated manipulation of immune and inflammatory responses in periodontal tissues which leads to the generation of a dysbiotic, subgingival biofilm community, and progression of periodontitis. The type 9 secretion system, lipid A modification, and the formation of outer membrane vesicles are important ...
Mike A. Curtis   +2 more
wiley   +1 more source

Association of EnterotoxigenicBacteroides fragilisInfection with Inflammatory Diarrhea [PDF]

open access: yesClinical Infectious Diseases, 2008
Diarrheal illnesses remain a leading cause of morbidity and mortality globally, with increasing recognition of long-term sequelae, including postinfectious irritable bowel syndrome and growth faltering, as well as cognitive deficits in children. Identification of specific etiologic agents is often lacking.
Cynthia L, Sears   +11 more
openaire   +2 more sources

Exploring the nexus: Clinical and physiological correlation between cardiovascular disease and colorectal cancer

open access: yesExperimental Physiology, EarlyView.
Abstract Colorectal cancer (CRC) and cardiovascular disease (CVD) are leading causes of morbidity and mortality worldwide, traditionally studied as distinct pathologies. However, emerging evidence suggests a significant physiological and molecular overlap between these conditions, indicating that they might share common pathophysiological pathways. The
Mohamad Bashir   +5 more
wiley   +1 more source

Monoclonal antibodies specific for Bacteroides fragilis enterotoxins BFT1 and BFT2 and their use in immunoassays. [PDF]

open access: yesPLoS ONE, 2017
We have developed 22 mouse IgG1 monoclonal antibodies (mAbs) against Bacteroides fragilis zinc metalloprotease toxins 1 and 2 (BFT1 and BFT2). Mice were immunized with recombinant BFT1 or BFT2 proteins with metalloprotease activity.
Saraspadee Mootien, Paul M Kaplan
doaj   +1 more source

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