Results 51 to 60 of about 2,879 (160)

The Keystone‐Pathogen Hypothesis Updated: The Role of Porphyromonas gingivalis in Periodontitis

Journal of Periodontal Research, EarlyView.
Porphyromonas gingivalis orchestrates a coordinated manipulation of immune and inflammatory responses in periodontal tissues which leads to the generation of a dysbiotic, subgingival biofilm community, and progression of periodontitis. The type 9 secretion system, lipid A modification, and the formation of outer membrane vesicles are important ...
Mike A. Curtis, James A. Garnett, Richard P. Darveau   +2 more
wiley   +1 more source

Complete Genome Sequence of an Enterotoxigenic Bacteroides fragilis Clinical Isolate [PDF]

Genome Announcements, 2015
ABSTRACT Here we present the complete genome sequence of Bacteroides fragilis isolate BOB25. It is an enterotoxigenic isolate that was obtained from a stool sample of a patient with dysbiosis.
Nikitina, Anastasia S., Kharlampieva, Daria D., Babenko, Vladislav V., Shirokov, Dmitriy A., Vakhitova, Maria T., Manolov, Aleksandr I., Shkoporov, Andrei N., Taraskina, Anastasia E., Manuvera, Valentin A., Lazarev, Vassili N., Kostryukova, Elena S.   +10 more
openaire   +2 more sources

Intratumoural Bacterial Co‐Occurrence is Associated With an Altered Tumour Immune Microenvironment and Poor Prognosis in Colorectal Cancer

Cancer Medicine, Volume 15, Issue 11, November 2026.
ABSTRACT Alterations in the composition of the gut microbiota have been associated with colorectal cancer (CRC), with growing evidence indicating that specific microbes can have an impact on the tumour microenvironment. In this study, we investigated the associations of an oral pathobiont consortium comprising P. stomatis, F. nucleatum sensu lato and P.
Marina Rubio Garcia, Vicky Bronnec, Maïwenn Kerdreux, William Rosenbaum, Thyra Löwenmark, Anna Löfgren‐Burström, Ingrid Ljuslinder, Sofia Edin, Richard Palmqvist   +8 more
wiley   +1 more source

Rapid and Sensitive Assay for Detection of Enterotoxigenic Bacteroides fragilis [PDF]

Journal of Clinical Microbiology, 1998
ABSTRACT Bacteroides fragilis is an obligatory anaerobic, gram-negative bacterium found among the normal intestinal flora of humans. Enterotoxigenic strains of B. fragilis (ETBF) have been associated with diarrheal diseases in humans and animals. The enterotoxin of ETBF induces fluid changes in
G, Zhang, A, Weintraub
openaire   +2 more sources

Monoclonal antibodies specific for Bacteroides fragilis enterotoxins BFT1 and BFT2 and their use in immunoassays. [PDF]

PLoS ONE, 2017
We have developed 22 mouse IgG1 monoclonal antibodies (mAbs) against Bacteroides fragilis zinc metalloprotease toxins 1 and 2 (BFT1 and BFT2). Mice were immunized with recombinant BFT1 or BFT2 proteins with metalloprotease activity.
Saraspadee Mootien, Paul M Kaplan
doaj   +1 more source

Intestinal bacteria and colorectal cancer: etiology and treatment

Gut Microbes, 2023
The etiology of colorectal cancer (CRC) is influenced by bacterial communities that colonize the gastrointestinal tract. These microorganisms derive essential nutrients from indigestible dietary or host-derived compounds and activate molecular signaling ...
Michael W. Dougherty, Christian Jobin
doaj   +1 more source

Cancer and Hypertension: Shared Mechanisms, Treatment Interactions, and Clinical Management

Cancer Medicine, Volume 15, Issue 10, October 2026.
ABSTRACT Cancer and hypertension (HTN) frequently coexist, and their relationship is increasingly recognized as a clinically relevant intersection between oncology and cardiovascular medicine. However, the extent to which this association reflects shared risk factors, common biological mechanisms, or treatment‐related effects remains incompletely ...
Peizhi Jia, Daxin Chen, Jingting Wang, Yupei Guo, Jinhong Liu, Jiumao Lin   +5 more
wiley   +1 more source

Association of EnterotoxigenicBacteroides fragilisInfection with Inflammatory Diarrhea [PDF]

Clinical Infectious Diseases, 2008
Diarrheal illnesses remain a leading cause of morbidity and mortality globally, with increasing recognition of long-term sequelae, including postinfectious irritable bowel syndrome and growth faltering, as well as cognitive deficits in children. Identification of specific etiologic agents is often lacking.
Cynthia L, Sears, Salequl, Islam, Amit, Saha, Maleka, Arjumand, Nur Haque, Alam, A S G, Faruque, M A, Salam, Jai, Shin, David, Hecht, Andrej, Weintraub, R Bradley, Sack, Firdausi, Qadri   +11 more
openaire   +2 more sources

Detection of non-enterotoxigenic and enterotoxigenic Bacteroides fragilis in stool samples from children in São Paulo, Brazil

Revista do Instituto de Medicina Tropical de São Paulo, 2003
Non-enterotoxigenic bacteria of the Bacteroides fragilis group and enterotoxigenic B. fragilis were identified from children with and without aqueous acute diarrhea.
Flávio Krzyzanowsky, Mario J. Avila-Campos   +1 more
doaj  

Microbiome and Tumor Microenvironment Interactions: Advances From Ecological Niches to Precision Oncology

Cancer Nexus, Volume 2, Issue 4, October 2026.
Tumor‐associated microbiota occupies spatially organized ecological niches and influence cancer progression by reshaping tumor‐cell signaling, metabolism, immunity, stromal remodeling, and therapeutic response. Integrating microbiome‐derived biomarkers, targeted microbial interventions, spatial multi‐omics, longitudinal monitoring, and AI may enable ...
Yiwen Zhang, Ji'an Liu, Jing Li, Xue Liu, Yang Su, Peng Luo, Yuhan Zhang, Zhengrui Li   +7 more
wiley   +1 more source