Results 1 to 10 of about 32,465 (166)

Dietary Salt Administration Decreases Enterotoxigenic Bacteroides fragilis (ETBF)-Promoted Tumorigenesis via Inhibition of Colonic Inflammation [PDF]

International Journal of Molecular Sciences, 2020
Consumption of a Western-type diet has been linked to gut-microbiota-mediated colon inflammation that constitutes a risk factor for colorectal cancer. A high salt diet (HSD) exacerbates IL-17A-induced inflammation in inflammatory bowel disease and other autoimmune diseases.
Ki-Jong Rhee, Soonjae Hwang, Minjeong Jo
exaly   +5 more sources

Protective Effects of Zerumbone on Colonic Tumorigenesis in Enterotoxigenic Bacteroides fragilis (ETBF)-Colonized AOM/DSS BALB/c Mice [PDF]

International Journal of Molecular Sciences, 2020
Chronic inflammation has been linked to colitis-associated colorectal cancer in humans. The human symbiont enterotoxigenic Bacteroides fragilis (ETBF), a pro-carcinogenic bacterium, has the potential to initiate and/or promote colorectal cancer. Antibiotic treatment of ETBF has shown promise in decreasing colonic polyp formation in murine models of ...
Ki-Jong Rhee, Soonjae Hwang, Chang Gun Lee   +2 more
exaly   +5 more sources

Enterotoxigenic Bacteroides fragilis: A Possible Etiological Candidate for Bacterially-Induced Colorectal Precancerous and Cancerous Lesions

Frontiers in Cellular and Infection Microbiology, 2020
Enterotoxigenic Bacteroides fragilis (ETBF) produces Bacteroides fragilis toxin (BFT), which is associated with acute diarrheal, inflammatory bowel disease, and colorectal cancer (CRC).
Samin Zamani, Leonardo Antonio Sechi, Seyedesomaye Jasemi   +2 more
exaly   +5 more sources

Colon Tumors in Enterotoxigenic Bacteroides fragilis (ETBF)-Colonized Mice Do Not Display a Unique Mutational Signature but Instead Possess Host-Dependent Alterations in the APC Gene [PDF]

Microbiology Spectrum, 2022
Enterotoxigenic Bacteroides fragilis (ETBF) is consistently found at higher frequency in individuals with sporadic and hereditary colorectal cancer (CRC) and induces tumorigenesis in several mouse models of CRC.
Jawara Allen, Axel Rosendahl Huber, Cayetano Pleguezuelos-Manzano, Jens Puschhof, Shaoguang Wu, Xinqun Wu, Charelle Boot, Aurelia Saftien, Heather M. O’Hagan, Hao Wang, Ruben van Boxtel, Hans Clevers, Cynthia L. Sears   +12 more
doaj   +5 more sources

KRAS Mutations Promote the Intratumoral Colonization of Enterotoxigenic Bacteroides Fragilis in Colorectal Cancer Through the Regulation of the miRNA3655/SURF6/IRF7/IFNβ Axis

Gut Microbes
KRAS mutations are associated with poor prognosis in colorectal cancer (CRC). Although the association between the gut microbiota and CRC has been extensively documented, it is unclear whether KRAS mutations can regulate the gut microbiota.
Yizhen Chen, Shengtao Lin, Changshun Yang   +2 more
exaly   +4 more sources

Carbapenem Resistance in Enterotoxigenic Bacteroides fragilis Isolated From Colonoscopy Candidates [PDF]

AMB Express
The present study aimed to determine the carbapenem resistance among Enterotoxigenic Bacteroides fragilis (ETBF) isolated from patients candidates to colonoscopy in Shiraz, Iran. A total of 201 stool samples were gathered from 201 patients. The detection
Ebrahim Fallahzadeh, Taher Azimi
exaly   +3 more sources

Prevalence of Enterotoxigenic Bacteroides fragilis in Patients With Colorectal Cancer: A Systematic Review and Meta-Analysis [PDF]

Frontiers in Cellular and Infection Microbiology
IntroductionThe gut microbiome, specifically enterotoxigenic Bacteroides fragilis (ETBF), has been reported to play a role in colorectal cancer development.
Linchong Yu
exaly   +4 more sources

G-protein coupled receptor 35 (GPR35) regulates the colonic epithelial cell response to enterotoxigenic Bacteroides fragilis [PDF]

Communications Biology, 2021
Boleij et al. show that G protein-coupled receptor 35 (GPR35) regulates the responses to enterotoxigenic Bacteroides fragilis (ETBF) in colonic epithelial cells.
Annemarie Boleij, Payam Fathi, William Dalton, Ben Park, Xinqun Wu, David Huso, Jawara Allen, Sepideh Besharati, Robert A. Anders, Franck Housseau, Amanda E. Mackenzie, Laura Jenkins, Graeme. Milligan, Shaoguang Wu, Cynthia L. Sears   +14 more
doaj   +2 more sources

Enterotoxigenic Bacteroides fragilis Induces the Stemness in Colorectal Cancer via Upregulating Histone Demethylase JMJD2B

Gut Microbes, 2020
The enrichment of Enterotoxigenic Bacteroides fragilis (ETBF) has been identified in CRC patients and associated with worse prognosis. Cancer stem cells (CSCs) play essential roles in CRC development.
Qin Yan Gao, Ying Xuan Chen, Jing-Yuan Fang   +2 more
exaly   +2 more sources

Quantitative profiling of colorectal cancer-associated bacteria reveals associations between fusobacterium spp., enterotoxigenic Bacteroides fragilis (ETBF) and clinicopathological features of colorectal cancer.

PLoS ONE, 2015
Various studies have presented clinical or in vitro evidence linking bacteria to colorectal cancer, but these bacteria have not previously been concurrently quantified by qPCR in a single cohort.
Katie S Viljoen, Amirtha Dakshinamurthy, Paul Goldberg, Jonathan M Blackburn   +3 more
doaj   +5 more sources