Results 81 to 90 of about 1,444 (144)

Integrating Aggregate Materials and Machine Learning Algorithms: Advancing Detection of Pathogen‐Derived Extracellular Vesicles

open access: yesAggregate, Volume 6, Issue 5, May 2025.
Pathogen‐derived extracellular vesicle detection: theoretical insights and advanced methodologies: This review explores the theoretical foundations and practical applications of pEV detection, emphasizing the challenges and innovative strategies involving novel aggregate materials and machine learning for enhanced diagnostic accuracy.
Lihan Lai   +6 more
wiley   +1 more source

Impact of microbiota in colorectal carcinogenesis: lessons from experimental models [PDF]

open access: yes, 2018
A role of gut microbiota in colorectal cancer (CRC) growth was first suggested in germ-free rats almost 50 years ago, and the existence of disease-associated bacteria (termed pathobionts) had becoming increasingly evident from experimental data of fecal ...
Linda Chia-Hui Yu   +2 more
core   +1 more source

Advances in Fecal Microbiota Transplantation for Gut Dysbiosis‐Related Diseases

open access: yesAdvanced Science, Volume 12, Issue 13, April 3, 2025.
This article reviews the use of fecal microbiota transplantation (FMT) to treat intestinal diseases like recurrent Clostridioides difficile infection (rCDI), inflammatory bowel disease (IBD), and irritable bowel syndrome (IBS). It discusses FMT's efficacy, influencing factors such as donor selection, recipient characteristics, and treatment protocols ...
Shuna Hou   +4 more
wiley   +1 more source

Microbiota as a mediator of cancer progression and therapy [PDF]

open access: yes, 2017
Complex and intricate circuitries regulate cellular proliferation, survival, and growth, and alterations of this network through genetic and epigenetic events result in aberrant cellular behaviors, often leading to carcinogenesis.
Jobin, Christian   +3 more
core   +2 more sources

Microsatellite Instability in the Tumor Microenvironment: The Role of Inflammation and the Microbiome

open access: yesCancer Medicine, Volume 14, Issue 8, April 2025.
The microbiome, an environmental factor, can contribute to DNA damage and affect mutation accumulation. Infections with genotoxin‐producing pathobionts can induce inflammation and oxidative stress through reactive nitrogen and oxygen species, which may influence MSI.
Elizabeth Vargas‐Castellanos   +1 more
wiley   +1 more source

Influence of bilberry-derived anthocyanidins on key regulators of colorectal cancer development. [PDF]

open access: yes, 2018
Colorectal cancer (CRC) is the third leading cause of cancer-related deaths within the United States. A variety of factors including exposure to environmental carcinogens, such as benzo[a]pyrene (B[a]P), dysbiosis of the gut microbiome and hereditary ...
Mudd, Ashley M.
core   +1 more source

Gut Microbiota in Colorectal Cancer: Associations, Mechanisms, and Clinical Approaches [PDF]

open access: yes, 2022
Colorectal cancer (CRC) is associated with the presence of particular gut microbes, as observed in many metagenomic studies to date. However, in most cases, it remains difficult to disentangle their active contribution to CRC from just a bystander role ...
Clevers, Hans   +2 more
core  

Влияние микробиоты человека на развитие колоректального рака [PDF]

open access: yes, 2019
This literature review analyzes the role of human microbiome in cancer development. We provide the data on the most common bacteria found in patients with colon cancer: Fusobacterium nucleatum, Bacteroidеs fragilis, and some strains of Escherichia coli ...
S. Gordeev S.   +5 more
core   +2 more sources

Applications of bacteriophages in precision engineering of the human gut microbiome

open access: yesEngineering Microbiology
As our understanding of the role of the gut microbiome in human diseases deepens, precision engineering of the gut microbiome using bacteriophages has gained significant attention.
Xiaoxian Kuang   +6 more
doaj   +1 more source

The Effects of the Gut Microbiota on the Host Chromatin Landscape [PDF]

open access: yes, 2017
The human gut microbiota is home to tens of trillions of microbes belonging to all three domains of life. The structure and expressed functions of this community have myriad effects on host physiology, metabolism, and immune function.
Semenkovich, Nicholas
core   +1 more source

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