Analysis of the Serotype and Genotype Correlation of VP1 and the 5′ Noncoding Region in an Epidemiological Survey of the Human Enterovirus B Species [PDF]
ABSTRACT The sequence identity of the enterovirus VP1 gene has been shown to correlate with the serotype concept. Enterovirus molecular typing methods are therefore often based on sequencing of the VP1 genomic region and monophyletic clustering of VP1 sequences of a homologous serotype.
Inge, Thoelen +7 more
openaire +2 more sources
Production of Cross‐Reactive Peptide Antibodies against Viral Capsid Proteins of Human Enterovirus B to Apply Diagnostic Reagent [PDF]
AbstractThe coxsackievirus group B (CVB) of the genus Enterovirus and the species human enterovirus B is a nonenveloped virus containing a single‐stranded positive‐sense RNA genome. Coxsackievirus has icosahedral symmetry and four capsid proteins, VP1, VP2, VP3, and VP4.
Soo-Young, Jeong +7 more
openaire +2 more sources
Sentinel surveillance for human enterovirus 71 in Sarawak, Malaysia: lessons from the first 7 years
Background A major outbreak of human enterovirus 71-associated hand, foot and mouth disease in Sarawak in 1997 marked the beginning of a series of outbreaks in the Asia Pacific region.
Yao Sik-King +13 more
doaj +1 more source
Background In the global eradication program for poliomyelitis, the laboratory diagnosis plays a critical role by isolating poliovirus (PV) from the stool samples of acute flaccid paralysis (AFP) cases. In this study, we developed a reverse transcription-
Wakita Takaji +6 more
doaj +1 more source
Evolutionary trajectory of the VP1 gene of human enterovirus 71 genogroup B and C viruses
From 1963 to 1986, human enterovirus 71 (HEV71) infections in the Netherlands were successively caused by viruses of subgenogroups B0, B1 and B2. A genogroup shift occurred in 1987, after which viruses of subgenogroups C1 and C2 were detected exclusively.
van der Sanden, S +4 more
openaire +3 more sources
Evidence for Frequent Recombination within SpeciesHuman Enterovirus BBased on Complete Genomic Sequences of All Thirty-Seven Serotypes [PDF]
ABSTRACTThe speciesHuman enterovirus B(HEV-B) in the familyPicornaviridaeconsists of coxsackievirus A9; coxsackieviruses B1 to B6; echoviruses 1 to 7, 9, 11 to 21, 24 to 27, and 29 to 33; and enteroviruses 69 and 73. We have determined complete genome sequences for the remaining 22 HEV-B serotypes whose sequences were not represented in public ...
M Steven, Oberste +2 more
openaire +2 more sources
Background: Recently, both sporadic and outbreak aseptic meningitis caused by enteroviruses have been reported in Zhejiang Province based on a surveillance system.
Yi Sun +7 more
doaj +1 more source
The complete nucleotide sequences of eight Human enterovirus B (HEV-B) strains were determined, representing five serotypes, E6, E7, E11, CVB3 and CVB5, which were isolated in the former Soviet Union between 1998 and 2002. All strains were mosaic recombinants and only the VP2–VP3–VP1 genome region was similar to that of the corresponding prototype HEV ...
Alexander N, Lukashev +5 more
openaire +2 more sources
Sensitive detection systems for infectious agents in xenotransplantation*
Abstract Xenotransplantation of pig cells, tissues, or organs may be associated with transmission of porcine microorganisms, first of all of viruses, to the transplant recipient, potentially inducing a disease (zoonosis). I would like to define detection systems as the complex of sample generation, sample preparation, sample origin, time of sampling ...
Joachim Denner
wiley +1 more source
Temporal Co-circulation Patterns of Respiratory Pathogens in South Africa, 2024: A Retrospective Analysis of Private Laboratory Surveillance Data [PDF]
Background and study aim: Respiratory tract infections cause substantial morbidity, and multiplex polymerase chain reaction (PCR) testing demonstrates concurrent circulation of multiple respiratory pathogens.
Somasundram Pillay
doaj +1 more source

