Results 21 to 30 of about 52,040 (206)

Construction of the Multi-Epitope HFMD Vaccine Based on an Attenuated CVB3 Vector and Evaluation of Immunological Responses in Mice [PDF]

Vaccines
Background/Objectives: Hand, foot, and mouth disease (HFMD) is a major public health concern primarily caused by human enterovirus A71 (EV-A71), coxsackievirus A16 (CVA16), coxsackievirus A6 (CVA6), and certain coxsackievirus B serotypes.
Jiayi Zheng, Huixiong Deng, Zhuangcong Liu, Hengyao Zhang, Guangzhi Liu, Yanlei Li, Jiacheng Zhu, Liming Gu, Dongdong Qiao, Gefei Wang, Rui Li   +10 more
doaj   +2 more sources

Activation of Host Cellular Signaling and Mechanism of Enterovirus 71 Viral Proteins Associated with Hand, Foot and Mouth Disease

Viruses, 2022
Enteroviruses are members of the Picornaviridae family consisting of human enterovirus groups A, B, C, and D as well as nonhuman enteroviruses. Human enterovirus type 71 (EV71) has emerged as a major cause of viral encephalitis, known as hand, foot, and ...
Subrat Kumar Swain, Subhasmita Panda, Basanta Pravas Sahu, Rachita Sarangi   +3 more
doaj   +2 more sources

Sequencing of 'untypable' enteroviruses reveals two new types, EV-77 and EV-78, within human enterovirus type B and substitutions in the BC loop of the VP1 protein for known types.

Journal of General Virology, 2003
The N-terminal part of VP1 was sequenced for 43 enterovirus isolates that could not initially be neutralized with LBM pools or in-house antisera. Most isolates were found to belong to human enterovirus type A (HEV-A) and HEV-B (18 isolates of each).
Chomel, Jj, Magnius, L., Lina, B., Aymard, M., Norder, H., Bjerregaard, L.   +5 more
core   +5 more sources

Human Enterovirus Group B Viruses Rely on Vimentin Dynamics for Efficient Processing of Viral Nonstructural Proteins [PDF]

Journal of Virology, 2020
A virus needs the host cell in order to replicate and produce new progeny viruses. For this, the virus takes over the host cell and modifies it to become a factory for viral proteins. Irrespective of the specific virus family, these proteins can be divided into structural and nonstructural proteins.
Turkki, Paula, Laajala, Mira, Flodström-Tullberg, Malin, Marjomäki, Varpu   +3 more
openaire   +5 more sources

Enterovirus species B isolates recovered from children with acute flaccid paralysis in Nigeria, 2010 and 2012

Journal of Clinical Virology Plus, 2022
In 2010 and 2012, between June and October (the peak period of enterovirus circulation in Nigeria), 59 archived enterovirus isolates (recovered as part of the Acute Flaccid Paralysis surveillance program) were randomly selected and typed in this study ...
T.O.C. Faleye, M.O. Adewumi, M.O. Japhet, U.E. George, O.M. David, A.O. Oluyege, J.A. Adeniji, O. Famurewa   +7 more
doaj   +1 more source

Human FcRn Is a Two-in-One Attachment-Uncoating Receptor for Echovirus 18

mBio, 2022
Virus-receptor interactions determine viral host range and tissue tropism. CD55 and human neonatal Fc receptor (FcRn) were found to be the binding and uncoating receptors for some of the echovirus-related enterovirus species B serotypes in our previous ...
Xiangpeng Chen, Xiao Qu, Congcong Liu, Yong Zhang, Guigen Zhang, Pu Han, Yali Duan, Qi Li, Liang Wang, Wenjing Ruan, Peiyi Wang, Wensheng Wei, George F. Gao, Xin Zhao, Zhengde Xie   +14 more
doaj   +1 more source

The Structure, Function, and Mechanisms of Action of Enterovirus Non-structural Protein 2C

Frontiers in Microbiology, 2020
Enteroviruses are a group of RNA viruses belonging to the family Picornaviridae. They include human enterovirus groups A, B, C, and D as well as non-human enteroviruses.
Shao-Hua Wang, Kuan Wang, Ke Zhao, Shu-Cheng Hua, Juan Du, Juan Du   +5 more
doaj   +1 more source

Neonates with acute liver failure have higher overall mortality but similar posttransplant outcomes as older infants

Liver Transplantation, EarlyView., 2022
Abstract Neonatal acute liver failure (ALF) carries a high mortality rate; however, little data exist on its peritransplant hospital course. This project aimed to identify factors associated with outcomes in neonates with ALF using large multicenter databases.
Swati Antala, Bridget Whitehead, Justin Godown, Matt Hall, Anna Banc‐Husu, Estella M. Alonso, Sarah A. Taylor   +6 more
wiley   +1 more source

Natural Recombination Event within the Capsid Genomic Region Leading to a Chimeric Strain of Human Enterovirus B [PDF]

Journal of Virology, 2007
ABSTRACT Recombination between two strains is a known phenomenon for enteroviruses replicating within a single cell. We describe a recombinant strain recovered from human stools, typed as coxsackievirus B4 (CV-B4) and CV-B3 after partial sequencing of the VP1 and VP2 coding regions, respectively.
Bouslama, Lamjed, Nasri, Dorsaf, Chollet, Lionel, Belguith, Khaoula, Bourlet, Thomas, Aouni, Mahjoub, Pozzetto, Bruno, Pillet, Sylvie   +7 more
openaire   +4 more sources

Comparative Seasonal Respiratory Virus Epidemic Timing in Utah

Viruses, 2020
Previous studies have found evidence of viral interference between seasonal respiratory viruses. Using laboratory-confirmed data from a Utah-based healthcare provider, Intermountain Health Care, we analyzed the time-specific patterns of respiratory ...
Zayne Y. Callahan, Trevor K. Smith, Celeste Ingersoll, Rebecca Gardner, E. Kent Korgenski, Chantel D. Sloan   +5 more
doaj   +1 more source