Results 31 to 40 of about 51,443 (168)

Monitoring antigenic variations of enterovirus 71: implications for virus surveillance and vaccine development. [PDF]

PLoS Neglected Tropical Diseases, 2014
Enterovirus 71 (EV71) causes life-threatening epidemics in Asia and can be phylogenetically classified into three major genogroups (A ∼ C) including 11 genotypes (A, B1 ∼ B5, and C1 ∼ C5).
Min-Yuan Chia, Wan-Yu Chung, Pai-Shan Chiang, Yeh-Sheng Chien, Mei-Shang Ho, Min-Shi Lee   +5 more
doaj   +1 more source

Effects of Nonpharmaceutical COVID-19 Interventions on Pediatric Hospitalizations for Other Respiratory Virus Infections, Hong Kong

Emerging Infectious Diseases, 2022
To determine the effects of nonpharmaceutical interventions (NPIs) for coronavirus disease on pediatric hospitalizations for infection with respiratory viruses other than severe acute respiratory syndrome coronavirus 2, we analyzed hospital data for ...
Susan S. Chiu, Benjamin J. Cowling, J.S. Malik Peiris, Eunice L.Y. Chan, Wilfred H.S. Wong, Kwok Piu Lee   +5 more
doaj   +1 more source

Molecular diagnosis of echovirus 30 as the etiological agent in an outbreak of aseptic meningitis in Panama: May – June 2008

Journal of Infection in Developing Countries, 2012
Introduction: Aseptic meningitis outbreaks are commonly caused by viral pathogens with enterovirus a common etiological agent. Between May and June of 2008, an outbreak of 173 cases of aseptic meningitis occurred in the Chiriqui Province of Panama ...
Alexander A Martinez, Juan Castillo, Mirla C Sanchez, Yamitzel Zaldivar, Yaxelis Mendoza, Maribel Tribaldos, Pablo Acosta, Rebecca E Smith, Juan Miguel Pascale   +8 more
doaj   +1 more source

Protective efficacy of VP1-specific neutralizing antibody associated with a reduction of viral load and pro-inflammatory cytokines in human SCARB2-transgenic mice. [PDF]

PLoS ONE, 2013
Hand-foot-mouth diseases (HFMD) caused by enterovirus 71 (EV71) and coxsackievirus 16 (CVA16) in children have now become a severe public health issue in the Asian-Pacific region.
Hsuen-Wen Chang, Yi-Wen Lin, Hui-Min Ho, Min-Han Lin, Chia-Chyi Liu, Hsiao-Yun Shao, Pele Chong, Charles Sia, Yen-Hung Chow   +8 more
doaj   +1 more source

Structural Basis for the Immunogenicity of the C-Terminus of VP1 of Echovirus 3 Revealed by the Binding of a Neutralizing Antibody

Viruses, 2022
Echovirus 3 (E3), a serotype of human enterovirus B (HEV-B), causes severe diseases in infants. Here, we determined the structures of E3 with a monoclonal antibody (MAb) 6D10 by cryo-EM to comprehensively understand the specificities and the ...
Shuai Qi, Wangjun Fu, Jinyan Fan, Li Zhang, Binyang Zheng, Kang Wang, Xiangxi Wang, Ling Zhu, Xinjian Li, Yuxia Zhang   +9 more
doaj   +1 more source

Selective Serotonin Reuptake Inhibitor Fluoxetine Inhibits Replication of Human Enteroviruses B and D by Targeting Viral Protein 2C [PDF]

Antimicrobial Agents and Chemotherapy, 2013
ABSTRACT Although the genus Enterovirus contains many important human pathogens, there is no licensed drug for either the treatment or the prophylaxis of enterovirus infections. We report that fluoxetine (Prozac)—a selective serotonin reuptake inhibitor—inhibits the replication of human enterovirus B (HEV ...
Ulferts, R., van der Linden, L., Thibaut, H.J., Lanke, K.H.W., Leyssen, P., Coutard, B., De Palma, A.M., Canard, B., Neyts, J., van Kuppeveld, F.J.M., van Kuppeveld, F.J.M.   +10 more
openaire   +5 more sources

Widespread circulation of echovirus 6 causing aseptic meningitis in paediatric patients in the area of Modena, Italy, in 2011

Microbiologia Medica, 2016
Introduction: Between May and November 2011, enterovirus RNA was detected in the cerebrospinal fluids (CSFs) of 72 children with signs of aseptic meningitis admitted to paediatric departments of different Hospitals of the prefecture of Modena, Emilia ...
Sara Tagliazucchi, Francesca Frascaro, Giulia Fregni Serpini, Nadia Nanni, Giulia Forbicini, Rita Magnani, William Gennari, Antonella Grottola, Fabio Rumpianesi, Monica Pecorari   +9 more
doaj   +1 more source

Genomic surveillance of enterovirus associated with aseptic meningitis cases in southern Spain, 2015–2018

Scientific Reports, 2021
New circulating Enterovirus (EV) strains often emerge through recombination. Upsurges of recombinant non-polio enteroviruses (NPEVs) associated with neurologic manifestations such as EVA71 or Echovirus 30 (E30) are a growing public health concern in ...
Fabiana Gámbaro, Ana Belén Pérez, Eduardo Agüera, Matthieu Prot, Luis Martínez-Martínez, María Cabrerizo, Etienne Simon-Loriere, Maria Dolores Fernandez-Garcia   +7 more
doaj   +1 more source

High frequency of enterovirus serotype circulation in a densely populated area of India

Journal of Infection in Developing Countries, 2013
Introduction: In the state of Uttar Pradesh in India, enteroviruses are a significant cause of infection presenting in endemic or epidemic forms. The present study aimed to use molecular methods to identify enterovirus serotypes in clinical specimens to
Arvind Kumar, Deepti Shukla, Shalini Srivastava, Mohammad Z Idris, Tapan N Dhole   +4 more
doaj   +1 more source

Computational Approach for Predicting Common Epitopes in the VP1 Structural Protein of Enterovirus Serotypes EV-D68, EV-D70, and EV-A71

Journal of Pure and Applied Microbiology, 2021
The three human Enterovirus serotypes D-68, D-70, and A-71, are common pathogens that are transmitted by fecal-oral and aerosol routes. These positive RNA viruses were known to exhibit high levels of genetic diversity and variability.
Rihabe Boussettine, Yassine Kasmi, Najwa Hassou, Hlima Bessi, Moulay Mustapha Ennaji   +4 more
doaj   +1 more source