Results 11 to 20 of about 28,006 (231)
Development of Three-Dimensional Human Intestinal Organoids as a Physiologically Relevant Model for Characterizing the Viral Replication Kinetics and Antiviral Susceptibility of Enteroviruses [PDF]
Enteroviruses are important causes of hand, foot, and mouth disease, respiratory infections, and neurological infections in human. A major hurdle for the development of anti-enterovirus agents is the lack of physiologically relevant evaluation platforms ...
J. Tsang +9 more
semanticscholar +2 more sources
Aim: to study of the frequency of isolation and determination of the spectrum of enterovirus serotypes excreted by children living in the North-Western region of Russia and children arriving in this region from unsafe territories.Materials and methods ...
N. I. Romanenkova +3 more
doaj +3 more sources
The Pyrimidine Analog FNC Potently Inhibits the Replication of Multiple Enteroviruses
Human enterovirus (EV) pathogens cause various contagious diseases such as hand, foot, and mouth disease, encephalitis, myocarditis, acute flaccid myelitis, pneumonia, and bronchiolitis, which have become serious health threats.
Na Xu +8 more
semanticscholar +2 more sources
Enterovirus Surveillance (EVSurv) in Germany
The major aim of the enterovirus surveillance (EVSurv) in Germany is to prove the absence of poliovirus circulation in the framework of the Global Polio Eradication Program (GPEI).
Kathrin Keeren +2 more
doaj +1 more source
Cross-Reactive Antibody Responses against Nonpoliovirus Enteroviruses
Enteroviruses (EVs) are common human pathogens. Although infection with EVs leads to cross-reactive antibodies, the clinical relevance of these antibodies is unclear given the estimated incidence of EV infections in the general population of one per year.
A. Rosenfeld +5 more
semanticscholar +1 more source
Enteroviruses and Type 1 Diabetes: Multiple Mechanisms and Factors?
Type 1 diabetes (T1D) is a chronic autoimmune disease characterized by insulin deficiency and resultant hyperglycemia. Complex interactions of genetic and environmental factors trigger the onset of autoimmune mechanisms responsible for development of ...
R. Lloyd, M. Tamhankar, Å. Lernmark
semanticscholar +1 more source
Viruses and Type 1 Diabetes: From Enteroviruses to the Virome
For over a century, viruses have left a long trail of evidence implicating them as frequent suspects in the development of type 1 diabetes. Through vigorous interrogation of viral infections in individuals with islet autoimmunity and type 1 diabetes ...
Sonia R Isaacs +8 more
semanticscholar +1 more source
Presence and Diversity of Different Enteric Viruses in Wild Norway Rats (Rattus norvegicus)
Rodents are common reservoirs for numerous zoonotic pathogens, but knowledge about diversity of pathogens in rodents is still limited. Here, we investigated the occurrence and genetic diversity of enteric viruses in 51 Norway rats collected in three ...
Sandra Niendorf +7 more
doaj +1 more source
Detection of enteroviruses during a 2018 hand, foot and mouth disease outbreak in Malaysia.
Hand, foot, and mouth disease (HFMD) is a common childhood disease caused by enteroviruses. In 2018, a HFMD outbreak in Malaysia affected over 76,000 children. In this study, we used RT-qPCR and CODEHOP PCR to detect the causative agents in 89 clinically
M. Lee +8 more
semanticscholar +1 more source
Avian hepatitis E virus (aHEV) is the major etiological agent of hepatitis-splenomegaly syndrome (HSS), big liver and spleen disease (BLSD), and hepatic rupture hemorrhage syndrome (HRHS) in chickens.
Fisayo Temilade Osamudiamen +5 more
doaj +1 more source

