Results 171 to 180 of about 3,151,493 (236)

Data‐Independent Acquisition Mass Spectrometry in Tumor Classification and Cancer Biomarker Research

Mass Spectrometry Reviews, EarlyView.
Abstract Cancer treatment is far from optimal also because current classification systems do not reflect the complex molecular status of the tumor and its phenotype in sufficient detail. To construct molecular tumor classifiers, omics tools provide complex molecular data reflecting many aspects from genotype to phenotype.
Jan Simonik, Petr Lapcik, Pavla Bouchalova, Pavel Bouchal   +3 more
wiley   +1 more source

Population structure and reproductive ecology of wild pigs at the northern edge of the North American invasive range. [PDF]

Sci Rep
Pruvot M, Salazar LG, Mainali C, Snow N, McKenzie H.   +4 more
europepmc   +1 more source

Analysis of Carbohydrates and Glycoconjugates by Matrix‐Assisted Laser Desorption/Ionization Mass Spectrometry: An Update for 2023–2024

Mass Spectrometry Reviews, EarlyView.
ABSTRACT The use of MALDI mass spectrometry for the analysis of carbohydrates and glycoconjugates is a well‐established technique and this comprehensive review is the twelfth update of the original article published in 1999 and brings coverage of the literature to the end of 2024.
David J. Harvey
wiley   +1 more source

Effect of the duration of visual exposure to the male on the reproductive performance of nulliparous guinea pigs. [PDF]

Braz J Vet Med
Pujada Abad HN, Collas Ostos E, Tamayo Diaz RC, Maguiña Maza RM, Linares Cabrera VJ, Valencia Bardales JC, Lucho-Cerga ME, Luyo Flores JH, Airahuacho-Bautista FE.   +8 more
europepmc   +1 more source

Navigating the Complexity: A Comprehensive Review of GSK‐3 Inhibition in Regenerative Medicine

Medicinal Research Reviews, EarlyView.
ABSTRACT Glycogen synthase kinase‐3 (GSK‐3) is a central regulator of numerous cellular signaling pathways, with critical roles in metabolism, proliferation, differentiation, and tissue regeneration. This review explores the multifaceted effects of pharmacological GSK‐3 inhibition across multiple body districts, focusing on its highly context‐dependent
Davide Schiroli, Alessia Merra, Chiara Marraccini, Lucia Merolle, Graziella Pellegrini, Eleonora Maurizi   +5 more
wiley   +1 more source

Development of mitochondrial mutator pigs exhibiting increased mitochondrial DNA mutations and premature aging via prime editing. [PDF]

Sci Adv
Chen F, Liang Y, Zheng W, Yao A, Wang N, Chen H, Zhuang Z, Lian M, Zhao Y, Ouyang Z, Zhou Z, Ge W, Liu Q, Ye Y, Lai L, Wang K.   +15 more
europepmc   +1 more source

Advancing Therapies for Mycobacterial Diseases: From Small Molecules to Host‐Directed Strategies

Medicinal Research Reviews, EarlyView.
ABSTRACT The global burden of multidrug‐resistant tuberculosis (MDR‐TB) and the rising incidence of nontuberculous mycobacterial (NTM) infections highlight the urgent need for innovative therapeutic strategies. Current treatments are prolonged, toxic, and increasingly compromised by resistance and limited diagnostic capacity.
Tânia Silva, Alessandra Aiello, Tonino Alonzi, M. Alice Carvalho, Vladimir Finger, Delia Goletti, Sven Hoffner, Yousra Kherabi, Jan Korabecny, Julia Kulczyńska, Agnieszka Kyzioł, Alicia Lacoma, Filomena Martins, Zorica Nanovic, Sepideh Hosseiniporgham, Martina Hrast Rambaher, Leonardo Antonio Sechi, Daria Smalchuk, Grażyna Stochel, Lydia Tabernero, Nancy L. Tateosian, Violeta Valcheva, Anamarija Zega, Mafalda Sarraguça   +23 more
wiley   +1 more source

Impact of increasing market pig weights in North America: a comprehensive review. [PDF]

J Anim Sci Biotechnol
Dorleku JB, Malgwi IH, Tayengwa T, Bohrer BM, de Souza Duarte M, Cánovas Á, Faucitano L, Juárez M.   +7 more
europepmc   +1 more source

Pre-natal stress and post-natal pain affect testis development in young pigs. [PDF]

, 2010
Duncan, Colin, Rutherford, Kenny, Ashworth, Cheryl, Hogg, Charis, Hoeks, Cindy   +4 more
core  

Functional Roles of Adenosine A2B and A3 Receptor Subtypes in the Bladder of Male Rats With A2B Receptor Deletion or Bladder Outlet Obstruction

Neurourology and Urodynamics, EarlyView.
ABSTRACT Purpose To investigate the adenosine receptor (AR) mechanism underlying bladder outlet obstruction (BOO)‐related bladder dysfunction, we examined the expression level of AR subtypes in bladder tissues, and the effects of AR subtypes A2B & A3 modulation on bladder activity using male BOO rats, and Dahl rats with A2B receptor deletion. Materials
Masahiro Kurobe, Ei‐ichiro Takaoka, Kanako Matsuoka, Shingo Kimura, Anne M. Robertson, Edwin K. Jackson, Lori A. Birder, Minoru Miyazato, Naoki Yoshimura   +8 more
wiley   +1 more source