Results 61 to 70 of about 82,235 (307)

Identification and characterization of previously described epitopes in HIV-1 subtypes B, C, F and BF in Brazil

Brazilian Journal of Infectious Diseases
Genetic analysis of HIV-1 is essential to improve treatment strategies and select epitopes for vaccine programs. The objective of this study was to determine whether known CD4+ and CD8+ epitopes were present in Brazilian HIV-1 strains. We used previously
Artur Trancoso Lopo de Queiroz, Luciane Amorim Santos, Domingos Ramon Moreau, Tulio de Oliveira, David I. Watkins, Bernardo Galvão-Castro, Luiz Carlos Junior Alcantara   +6 more
doaj   +1 more source

Immunogenicity of HIV-1-Based Virus-Like Particles with Increased Incorporation and Stability of Membrane-Bound Env

Vaccines, 2021
An optimal prophylactic vaccine to prevent human immunodeficiency virus (HIV-1) transmission should elicit protective antibody responses against the HIV-1 envelope glycoprotein (Env).
Christopher A. Gonelli, Hannah A. D. King, Charlene Mackenzie, Secondo Sonza, Rob J. Center, Damian F. J. Purcell   +5 more
doaj   +1 more source

IMF-ENV

IMF Working Papers
IMF-ENV is a global dynamic computable general equilibrium (CGE) model developed by the IMF's Research Department. The model features a database of 160 countries and regions, along with 76 sectors, and can be calibrated to a wide range of country-sector combinations.
Jean Chateau, Hugo Rojas-Romagosa, Sneha Thube, Dominique van der Mensbrugghe   +3 more
openaire   +1 more source

Mechanisms for Env Glycoprotein Acquisition by Retroviruses [PDF]

AIDS Research and Human Retroviruses, 2011
A mandatory step in the formation of an infectious retroviral particle is the acquisition of its envelope glycoprotein (Env). This step invariably occurs by Env positioning itself in the host membrane at the location of viral budding and being incorporated along with the host membrane into the viral particle.
openaire   +2 more sources

Adaptive Macroscopic Ensemble Allocation for Robot Teams Monitoring Spatiotemporal Processes

Advanced Intelligent Systems, EarlyView.
We propose an online, environment feedback‐driven macroscopic ensemble approach to adapt robot team task allocation in spatiotemporal environments by controlling robot populations rather than assigning individual robots, all while maintaining robust team performance even for small teams. Our simulation and experimental results show better or comparable
Victoria Edwards, Thales C. Silva, M. Ani Hsieh   +2 more
wiley   +1 more source

Pathogenesis of Vasculitis in env-pX Rats

Annals of Vascular Diseases, 2012
Transgenic rats carrying the env-pX gene of human T-cell leukemia virus type I (env-pX rats) develop necrotizing angiitis resembling human polyarteritis nodosa (PN). In the development of vasculitis in these rats, the thymus plays an important role. In this review, we provide an outline of the pathogenesis of vasculitis observed in env-pX rats, and ...
Ishizu, Akihiro, Yoshiki, Takashi
openaire   +3 more sources

Driver Behavior Modeling with Subjective Risk‐Driven Inverse Reinforcement Learning

Advanced Intelligent Systems, EarlyView.
A subjective risk‐driven inverse reinforcement learning framework is proposed to model driver decision‐making. It infers drivers' risk perception and risk tolerance from driving data. A learnable risk threshold is used to regulate decisions, enabling interpretable and human‐like driving behavior decisions.
Yang Liang, Zichao Wang, Zhiwei He, Qingquan Wei, Yong Zuo, Linzhen Nie, Zhishuai Yin   +6 more
wiley   +1 more source

HIV protein profile characteristics in patients with first-time detected infection

Инфекция и иммунитет
The HIV-infection continues to be one of the most large-scale epidemics worldwide. Many techniques have been developed to detect this disease, but the Western blot based on the identification of specific viral proteins remains the most commonly used ...
V. S. Davydenko, Yuliia V. Ostankova, A. N. Schemelev, E. N. Serikova, A. A. Totolian   +4 more
doaj   +1 more source

Cardiovascular Exercise Drives Neuroprotection in a Mouse Model of Spinocerebellar Ataxia 1 Via Rescue of Aberrant Splicing

Annals of Neurology, EarlyView.
Objective Spinocerebellar ataxia 1 (SCA1) is a fatal hereditary neurodegenerative disorder with no approved therapies, and gene‐targeting strategies have thus far failed in clinical trials. Exercise remains the only intervention shown to provide clinical benefit in patients with spinocerebellar ataxias (SCAs), yet the underlying mechanisms remain ...
Isabel Soto, Michael Bonomo, Brianna S. Nelthrope, Benjamin D. Carr, Emma Palmer, Mariana Sierra, Ilkim Erturk, David Peppercorn, Eleonor Cox, Tiare K. Vasconcellos, Henry L. Paulson, Hannah K. Shorrock, Sharan R. Srinivasan   +12 more
wiley   +1 more source

The HIV Env-mediated fusion reaction

Biochimica et Biophysica Acta (BBA) - Biomembranes, 2003
The current general model of HIV viral entry involves the binding of the trimeric viral envelope glycoprotein gp120/gp41 to cell surface receptor CD4 and chemokine co-receptor CXCR4 or CCR5, which triggers conformational changes in the envelope proteins.
Gallo, Stephen A., Finnegan, Catherine M., Viard, Mathias, Raviv, Yossef, Dimitrov, Antony, Rawat, Satinder S., Puri, Anu, Durell, Stewart, Blumenthal, Robert   +8 more
openaire   +2 more sources