Results 41 to 50 of about 503 (172)

Early‐life and chronic exposure to high‐fat diet alters noradrenergic and glutamatergic neurotransmission in the male rat amygdala and hippocampus under cognitive challenges

Journal of Neuroscience Research, Volume 102, Issue 6, June 2024.
High‐fat diets alter amygdala and hippocampus neurochemistry in juvenile male rats. Rats with metabolic changes show enhanced odor aversion memory, linked to elevated noradrenergic and glutamatergic neurotransmission. This highlights intricate connections between obesogenic diets, neurochemistry, and cognition, implying that metabolic dysfunctions can ...
Daniel Osorio‐Gómez, Claudia I. Perez, Pamela Salcedo‐Tello, Arturo Hernández‐Matias, Susana Hernández‐Ramírez, Benjamin Arroyo, Gustavo Pacheco‐López, Ranier Gutierrez, Federico Bermúdez‐Rattoni, Kioko Guzmán‐Ramos, OBETEEN Consortium, Guillaume Ferreira, Gustavo Pacheco‐Lopez, Etienne Coutureau, Ranier Gutierrez, Pascal Barat, Federico Bermudez‐Rattoni, Gwenaelle Catheline, Claudia I. Pérez, Pauline Lafenêtre, Daniel Osorio‐Gomez, Kioko Guzman‐Ramos, Fabien Naneix, Ernesto Sanz‐Arigita, Ioannis Bakoyiannis   +24 more
wiley   +1 more source

Neuroinflammation, AD, and Dementia

, 2010
International Journal of Alzheimer’s Disease, Volume 2010, Issue 1, 2010.
Marcella Reale, Talma Brenner, Nigel H. Greig, Nibaldo Inestrosa, Diana Paleacu   +4 more
wiley   +1 more source

Terapia génica y reprogramación celular en modelos animales de envejecimiento cerebral [PDF]

, 2019
En humanos y ratas, el envejecimiento está asociado a un progresivo deterioro del aprendizaje y la memoria espacial. Además, el envejecimiento trae aparejado cambios morfométricos en el hipocampo, una estructura clave en la formación y consolidación de la memoria.
openaire   +4 more sources

Neuronal surface P antigen (NSPA) modulates postsynaptic NMDAR stability through ubiquitination of tyrosine phosphatase PTPMEG

BMC Biology, 2020
Background Cognitive dysfunction (CD) is common among patients with the autoimmune disease systemic lupus erythematosus (SLE). Anti-ribosomal P autoantibodies associate with this dysfunction and have neuropathogenic effects that are mediated by cross ...
Sofía Espinoza, Sebastián B. Arredondo, Francisca Barake, Francisco Carvajal, Fernanda G. Guerrero, Fabian Segovia-Miranda, David M. Valenzuela, Ursula Wyneken, Alejandro Rojas-Fernández, Waldo Cerpa, Loreto Massardo, Lorena Varela-Nallar, Alfonso González   +12 more
doaj   +1 more source

Biomarkers of Oxidative Stress, Inflammation, and Brain Damage in Mexican Women over 60 Years of Age with Obesity

Revista de Investigación Clínica
Background: Obesity and aging are risk factors for chronic degenerative diseases that favor neuroinflammation leading to cognitive and motor impairment. Mexico ranks second in obesity worldwide, being more prevalent in the female population.
Armando Luna-López, Julián de Jesús Lira-Rotstein, Raúl Librado-Osorio, Roberto Santín-Márquez, Óscar Rosas-Carrasco, Mina Königsberg   +5 more
doaj   +1 more source

WNT signalling in neuronal maturation and synaptogenesis

Frontiers in Cellular Neuroscience, 2013
The Wnt signaling pathway plays a role in the development of the central nervous system (CNS) and growing evidence indicates that Wnts also regulates the structure and function of the adult nervous system.
Silvana Beatriz Rosso, NIBALDO C. INESTROSA, Silvana Beatriz Rosso   +2 more
doaj   +1 more source

Serine–Arginine Protein Kinase SRPK2 Modulates the Assembly of the Active Zone Scaffolding Protein CAST1/ERC2

Cells, 2019
Neurons release neurotransmitters at a specialized region of the presynaptic membrane, the active zone (AZ), where a complex meshwork of proteins organizes the release apparatus.
Duxan Arancibia, Matias Lira, Yocelin Cruz, Daniela P. Barrera, Carolina Montenegro-Venegas, Juan A. Godoy, Craig C. Garner, Nibaldo C. Inestrosa, Eckart D. Gundelfinger, Pedro Zamorano, Viviana I. Torres   +10 more
doaj   +1 more source

The theory of oxidative stress as a direct cause of cell aging

Medisur, 2018
The loss of functional capacities, aging and death are inherent to all living matter due to metabolism and other factors causing the formation of substances which damage irreversibly cell structure components.
Milagros Lisset León Regal, Raúl Cedeño Morales, Rodolfo Javier Rivero Morey, Jeisy Rivero Morey, Diana Laura García Pérez, Leissay Bordón González   +5 more
doaj   +2 more sources

Proteasome Dependent Actin Remodeling Facilitates Antigen Extraction at the Immune Synapse of B Cells

Frontiers in Immunology, 2019
Engagement of the B cell receptor (BCR) with surface-tethered antigens leads to the formation of an immune synapse (IS), where cell signaling and antigen uptake are tightly coordinated.
Jorge Ibañez-Vega, Felipe Del Valle Batalla, Juan José Saez, Andrea Soza, Andrea Soza, Maria-Isabel Yuseff   +5 more
doaj   +1 more source

Envejecimiento fotoenvejecimiento

Revista de la Asociación Colombiana de Dermatología y Cirugía Dermatológica, 1999
Se define como envejecimiento la pérdida progresiva de todas las funciones del organismo, haciéndolo más vulnerable a los factores ambientales externos, hecho que en biología se conoce como entropía celular.
María Mélida Durán
doaj