Results 21 to 30 of about 204,916 (172)

Envejecimiento Celular - Alzheimer

open access: yesOdontología Sanmarquina, 2005
Históricamente, El término enfermedad de Alzheimer se usó si el padecimiento empezaba antes de los 65 años de edad, y demencia senil si lo hacía después.
Luis Cuadrao Zavalela
doaj   +1 more source

Selective Surface and Intraluminal Localization of Wnt Ligands on Small Extracellular Vesicles Released by HT-22 Hippocampal Neurons

open access: yesFrontiers in Cell and Developmental Biology, 2021
The Wnt signaling pathway induces various responses underlying the development and maturation of the nervous system. Wnt ligands are highly hydrophobic proteins that limit their diffusion through an aqueous extracellular medium to a target cell ...
Viviana I. Torres   +5 more
doaj   +1 more source

Wnt3a ligand facilitates autophagy in hippocampal neurons by modulating a novel GSK-3β-AMPK axis

open access: yesCell Communication and Signaling, 2018
Background In the adult central nervous system (CNS), Wnt signaling regulates dendritic structure and synaptic plasticity. The Wnt signaling pathway can be divided into the canonical (β-catenin-dependent) and non-canonical pathways.
Juvenal A. Ríos   +2 more
doaj   +1 more source

Presymptomatic Treatment With Andrographolide Improves Brain Metabolic Markers and Cognitive Behavior in a Model of Early-Onset Alzheimer’s Disease

open access: yesFrontiers in Cellular Neuroscience, 2019
Alzheimer’s disease (AD) is the most common type of dementia. The onset and progression of this pathology are correlated with several changes in the brain, including the formation of extracellular aggregates of amyloid-beta (Aβ) peptide and the ...
Pedro Cisternas   +6 more
doaj   +1 more source

Chronic hypoxia induces the in vivo activation of the Wnt/β-catenin signaling pathway and stimulates hippocampal neurogenesis in wild-type and APPswe-PS1deltaE9 transgenic mice

open access: yesFrontiers in Cellular Neuroscience, 2014
Hypoxia modulates proliferation and differentiation of cultured embryonic and adult stem cells, an effect that includes β-catenin a key component of the canonical Wnt signaling pathway.
Lorena eVarela-Nallar   +6 more
doaj   +1 more source

Pro-Tumoral Functions of Autophagy Receptors in the Modulation of Cancer Progression

open access: yesFrontiers in Oncology, 2021
Cancer progression involves a variety of pro-tumorigenic biological processes including cell proliferation, migration, invasion, and survival. A cellular pathway implicated in these pro-tumorigenic processes is autophagy, a catabolic route used for ...
Cristóbal Cerda-Troncoso   +3 more
doaj   +1 more source

Reciclaje celular y envejecimiento [PDF]

open access: yes, 2019
El envejecimiento es un proceso biológico que depende en gran medida de la genética, aunque, también se ve determinado por el entorno físico y social que le rodea.
Peralbo Calero, Ángela
core   +1 more source

El envejecimiento: ¿Podemos frenarlo? Telómeros/Telomerasa, Senescencia Celular Primera Parte

open access: yes, 2023
Todos los seres vivos sufren un declinio fisiológico sistémico después de la ontogenia, caracterizado como “envejecimiento”. El proceso del envejecimiento es multifactorial, probablemente ocasionado por una miríada de factores, que interactúan y con ...
Garrido, María del Rosario
core   +1 more source

Wnt Signaling Pathway Dysregulation in the Aging Brain: Lessons From the Octodon degus

open access: yesFrontiers in Cell and Developmental Biology, 2020
Wnt signaling constitutes a fundamental cellular and molecular pathway, necessary from proper embryogenesis to function-maintenance of fully developed complex organisms.
Nibaldo C. Inestrosa   +4 more
doaj   +1 more source

Identification of an Evolutionarily Conserved Ankyrin Domain-Containing Protein, Caiap, Which Regulates Inflammasome-Dependent Resistance to Bacterial Infection

open access: yesFrontiers in Immunology, 2017
Many proteins contain tandemly repeated modules of several amino acids, which act as the building blocks that form the underlying architecture of a specific protein-binding interface.
Sylwia D. Tyrkalska   +8 more
doaj   +1 more source

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