Results 21 to 30 of about 503 (172)
Frontiers in Cell and Developmental Biology, 2022 Hedgehog proteins (Hhs) secretion from apical and/or basolateral domains occurs in different epithelial cells impacting development and tissue homeostasis.
Lisette Sandoval +9 more
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Hormetic-Like Effects of L-Homocysteine on Synaptic Structure, Function, and Aβ Aggregation
Pharmaceuticals, 2020 Alzheimer’s Disease (AD) is the primary cause of dementia among the elderly population. Elevated plasma levels of homocysteine (HCy), an amino acid derived from methionine metabolism, are considered a risk factor and biomarker of AD and other types
Carla Montecinos-Oliva +4 more
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Frontiers in Cell and Developmental Biology, 2021 The Wnt signaling pathway induces various responses underlying the development and maturation of the nervous system. Wnt ligands are highly hydrophobic proteins that limit their diffusion through an aqueous extracellular medium to a target cell ...
Viviana I. Torres +5 more
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Wnt3a ligand facilitates autophagy in hippocampal neurons by modulating a novel GSK-3β-AMPK axis
Cell Communication and Signaling, 2018 Background In the adult central nervous system (CNS), Wnt signaling regulates dendritic structure and synaptic plasticity. The Wnt signaling pathway can be divided into the canonical (β-catenin-dependent) and non-canonical pathways.
Juvenal A. Ríos +2 more
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Frontiers in Cellular Neuroscience, 2019 Alzheimer’s disease (AD) is the most common type of dementia. The onset and progression of this pathology are correlated with several changes in the brain, including the formation of extracellular aggregates of amyloid-beta (Aβ) peptide and the ...
Pedro Cisternas +6 more
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Bases moleculares y celulares del envejecimiento
ARS MEDICA Revista de Ciencias Médicas, 2016 Sin resumen ...
Claudia Metz Baer, Marcela Bravo Zehnder
openaire +3 more sources
Frontiers in Cellular Neuroscience, 2014 Hypoxia modulates proliferation and differentiation of cultured embryonic and adult stem cells, an effect that includes β-catenin a key component of the canonical Wnt signaling pathway.
Lorena eVarela-Nallar +6 more
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Pro-Tumoral Functions of Autophagy Receptors in the Modulation of Cancer Progression
Frontiers in Oncology, 2021 Cancer progression involves a variety of pro-tumorigenic biological processes including cell proliferation, migration, invasion, and survival. A cellular pathway implicated in these pro-tumorigenic processes is autophagy, a catabolic route used for ...
Cristóbal Cerda-Troncoso +3 more
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Wnt Signaling Pathway Dysregulation in the Aging Brain: Lessons From the Octodon degus
Frontiers in Cell and Developmental Biology, 2020 Wnt signaling constitutes a fundamental cellular and molecular pathway, necessary from proper embryogenesis to function-maintenance of fully developed complex organisms.
Nibaldo C. Inestrosa +4 more
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Frontiers in Immunology, 2017 Many proteins contain tandemly repeated modules of several amino acids, which act as the building blocks that form the underlying architecture of a specific protein-binding interface.
Sylwia D. Tyrkalska +8 more
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