Results 81 to 90 of about 1,454,677 (334)

Interplay of space radiation and microgravity in DNA damage and DNA damage response [PDF]

, 2017
In space, multiple unique environmental factors, particularly microgravity and space radiation, pose constant threat to the DNA integrity of living organisms.
Lu, Tao, Moreno-Villanueva, María, Wong, Michael, Wu, Honglu, Zhang, Ye   +4 more
core   +2 more sources

Environmental versus extra‐organismal DNA [PDF]

Molecular Ecology, 2021
Jan Pawlowski, Jan Pawlowski, Florian Altermatt, Florian Altermatt, Laure Apothéloz-Perret-Gentil   +4 more
openaire   +4 more sources

The nicotinamide hypothesis revisited—plant defense signaling integrating PARP, nicotinamide, nicotinic acid, epigenetics, and glutathione

FEBS Letters, EarlyView.
Nicotinamide (NIC) and nicotinic acid (NIA) are proposed as stress signaling compounds in plants. Oxidative stress may lead to single strand breaks (SSB) in DNA, which activate poly(ADP‐ribose) polymerase (PARP). NIC and NIA are then formed from NAD. NIC and NIA can promote epigenetic changes leading to the expression of defense genes specific for the ...
Torkel Berglund, Anna B. Ohlsson
wiley   +1 more source

The applicability of eDNA metabarcoding approaches for sessile benthic surveying in the Kimberley region, north‐western Australia

Environmental DNA, 2022
The application of environmental DNA technologies is a promising new approach to rapidly audit biodiversity across large‐scale, remote regions. Here, we examine the efficacy of a dual‐assay eDNA metabarcoding approach for sessile benthic bioassessments ...
Katrina M. West, Arne A. S. Adam, Nicole White, William D. Robbins, Daniel Barrow, Adrian Lane, Zoe T.Richards   +6 more
doaj   +1 more source

Joint single-cell DNA accessibility and protein epitope profiling reveals environmental regulation of epigenomic heterogeneity. [PDF]

, 2018
Here we introduce Protein-indexed Assay of Transposase Accessible Chromatin with sequencing (Pi-ATAC) that combines single-cell chromatin and proteomic profiling. In conjunction with DNA transposition, the levels of multiple cell surface or intracellular
Chang, Howard Y, Chen, Xingqi, Choudhry, Hani, Giaccia, Amato J, Greenleaf, William J, LaGory, Edward L, Litzenburger, Ulrike M, Schep, Alicia N, Wei, Yuning   +8 more
core   +2 more sources

Consequences of environmental DNA pooling

, 2020
DNA-based techniques are increasingly used to assess biodiversity both above- and belowground. Most effort has focussed on bioinformatics and sample collection, whereas less is known about the consequences of mixing collected environmental DNA (eDNA), post-extraction and pre-PCR.
Duane A. Peltzer, Ian A. Dickie, Ralph Wainer, Hayley J. Ridgway, E. Eirian Jones   +4 more
openaire   +2 more sources

Single cis‐elements in brassinosteroid‐induced upregulated genes are insufficient to recruit both redox states of the BIL1/BZR1 DNA‐binding domain

FEBS Letters, EarlyView.
Phytohormone brassinosteroid‐induced gene regulation by the transcription factor BIL1/BZR1 involves redox‐dependent DNA‐binding alternation and interaction with the transcription factor PIF4. The reduced BIL1/BZR1 dimer binds preferred cis‐elements, while oxidation alters its oligomerization state and disrupts DNA‐binding ability.
Shohei Nosaki, Masae Ohtsuka, Takeshi Nakano, Masaru Tanokura, Takuya Miyakawa   +4 more
wiley   +1 more source

Potential Role of Photochemistry in Environmental DNA Degradation. [PDF]

Environ Sci Technol Lett
ISSN:2328 ...
Ballmer E, McNeill K, Deiner K.
europepmc   +3 more sources

RAD6-RAD18-RAD5-pathway-dependent tolerance to chronic low-dose ultraviolet light [PDF]

, 2009
In nature, organisms are exposed to chronic low- dose ultraviolet light ( CLUV) as opposed to the acute high doses common to laboratory experiments. Analysis of the cellular response to acute high-dose exposure has delineated the importance of direct DNA
Carr, Antony M, Hishida, T, Iwasaki, H, Kubota, Y   +3 more
core   +1 more source

From lactation to malignancy: A comparison between healthy and cancerous breast gland at single‐cell resolution reveals new issues for tumorigenesis

FEBS Letters, EarlyView.
Single‐cell RNA sequencing reveals an opposite role of SLPI in basal tumors based on metastatic spread, along with shared activation of specific regulons in cancer cells and mature luminal lactocytes, as well as downregulation of MALAT1 and NEAT1 in the latter.
Pietro Ancona, Carlo M. Bergamini, Carlo Ferrari, Stefano Volinia, Nicoletta Bianchi   +4 more
wiley   +1 more source