Cyclic nucleotide specificity of the activator and catalytic sites of a cGMP-stimulated cGMP phosphodiesterase from Dictyostelium discoideum [PDF]
, 1985 The cellular slime mold Dictyostelium discoideum has an intracellular phosphodiesterase which specifically hydrolyzes cGMP. The enzyme is activated by low cGMP concentrations, and is involved in the reduction of chemoattractant-mediated elevations of ...
Baraniak, Janina, +8 more
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Iron-Dependent Trafficking of 5-Lipoxygenase and Impact on Human Macrophage Activation
Frontiers in Immunology, 2019 5-lipoxygenase (5-LOX) is a non-heme iron-containing dioxygenase expressed in immune cells that catalyzes the two initial steps in the biosynthesis of leukotrienes.
Beatrice Dufrusine +13 more
doaj +1 more source
Scientific Reports, 2023 The assembly state of enzymes is gaining interest as a mechanism for regulating the function of enzymes in living cells. One of the current topics in enzymology is the relationship between enzyme activity and the assembly state due to liquid–liquid phase
Tomoto Ura +7 more
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A Shift in Central Metabolism Accompanies Virulence Activation in Pseudomonas aeruginosa. [PDF]
, 2020 The availability of energy has significant impact on cell physiology. However, the role of cellular metabolism in bacterial pathogenesis is not understood.
Chacko, Jenu V +4 more
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Activity of glucose oxidase functionalized onto magnetic nanoparticles [PDF]
, 2005 BACKGROUND: Magnetic nanoparticles have been significantly used for coupling with biomolecules, due to their unique properties. METHODS: Magnetic nanoparticles were synthesized by thermal co-precipitation of ferric and ferrous chloride using two ...
Irudayaraj, Joseph +2 more
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The effects of nitroxyl (HNO) on soluble guanylate cyclase activity: interactions at ferrous heme and cysteine thiols [PDF]
, 2009 It has been previously proposed that nitric oxide (NO) is the only biologically relevant nitrogen oxide capable of activating the enzyme soluble guanylate cyclase (sGC). However, recent reports implicate HNO as another possible activator of sGC.
Adrian J. Hobbs +85 more
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An Extended Polyanion Activation Surface in Insulin Degrading Enzyme. [PDF]
PLoS ONE, 2015 Insulin degrading enzyme (IDE) is believed to be the major enzyme that metabolizes insulin and has been implicated in the degradation of a number of other bioactive peptides, including amyloid beta peptide (Aβ), glucagon, amylin, and atrial natriuretic ...
Eun Suk Song +9 more
doaj +1 more source
Scanning Electron Microscopic Study of the Tongue Papillae Formation
Central Asian Journal of Medical Sciences, 2017 Objectives: To clarify the morphology of the tongue papillae formation and the metabolic characteristics along the papillae distribution in rats. Methods: The experiment was designed as a cross-sectional study and included; a scanning electron and light ...
Shine-Od Dalkhsuren +2 more
doaj +1 more source
How does conformational flexibility influence key structural features involved in activation of anaplastic lymphoma kinase? [PDF]
, 2014 Anaplastic Lymphoma Kinase (ALK) plays a major role in developing tumor processes and therefore has emerged as a validated therapeutic target. Applying atomistic molecular dynamics simulations on the wild type enzyme and the nine most frequently ...
Adcock +28 more
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Activity of enzymes and fitness variation [PDF]
Genetics Selection Evolution, 1989 Uploaded by Plazi for TaxoDros. We do not have abstracts.
M. Milošević, D. Marinković
openaire +5 more sources