Results 151 to 160 of about 6,124,915 (260)

Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model

FEBS Open Bio, EarlyView.
This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito, Haduki Asano, Ayano Ueki, Joe Sakamoto, Yasuhiro Kamei, Hayato Tokumoto, Ayaka Yazawa, Shigeki Kamitani   +7 more
wiley   +1 more source

Artificial intelligence and automation in enzyme engineering: evolution, advances, and future perspectives. [PDF]

Bioresour Bioprocess
Hao K, Liu J, Tang H, Zhang Y, Sun Y, Zhang H, Wang J, Liu P, Luo J, Zhao J.   +9 more
europepmc   +1 more source

KDAC6 alters cell morphology and motility through positive and negative modulation of F‐actin distribution

FEBS Open Bio, EarlyView.
KDAC6 has been associated with cell motility and actin structures, but specific domain contributions are not established. The two catalytic domains have differential effects on motility and F‐actin regulation, affecting cortical F‐actin density, motility, stress fibers, and cell spreading.
Taylor V. Joseph, Andrea B. Pham, Kiara E. Bornes, Razan H. Hammad, Chelsea A. Rousseve‐Ross, Thomas M. Huckaba, Terry J. Watt, Tasha B. Toro   +7 more
wiley   +1 more source

Beyond enzyme engineering: ordered enzyme immobilization drives enhanced productivity <i>in vitro</i>. [PDF]

Front Bioeng Biotechnol
Wong M, Neuman TG, Hoque MA, Moraïs S, Bayer E, Belfort G, Koffas M.   +6 more
europepmc   +1 more source

Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA

FEBS Open Bio, EarlyView.
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley   +1 more source

A Novel Histidinol Phosphate Phosphatase, Catalyzing the Penulimate Step of the Histidine Biosynthesis Pathway, from a Hyperthermophilic Archaeon Thermococcus onnurineus NA1

, 2007
The entire gene cluster encoding enzymes involved in the histidine biosynthesis was analyzed in the complete genome of the hyperthermophilic archaeon Thermococcus onnurineus NA1 and it was found that an essential gene to encode the histidinol phosphate ...
이정현, 강성균, 조요나, 이현숙   +3 more
core  

High-level amyrin production in <i>Yarrowia lipolytica</i> via metabolic and enzyme engineering. [PDF]

Synth Syst Biotechnol
Elsharawy H, Abdullah CN, Yin X, Zhou J.
europepmc   +1 more source

Delivery of DNA‐encoded vaccines and proteins in mice using cutaneous suction‐mediated transfection

FEBS Open Bio, EarlyView.
Cutaneous suction‐mediated transfection in mice for delivery of DNA‐encoded vaccines and proteins. A critical limitation of DNA vaccines and other therapeutics is transfection in vivo to produce the encoded antigens or therapeutic proteins. Cutaneous suction‐based methods have demonstrated effectiveness in many animal models and have been successfully ...
Emran O. Lallow, Isabel Brandtjen, Yaxin Mo, Melissa Gulley, Louis Osorio, Sagar Kudchodkar, Nandita C. Jhumur, Christine C. Roberts, Lisa K. Denzin, David I. Shreiber, Biju Parekkadan, Hao Lin, Joel N. Maslow   +12 more
wiley   +1 more source

Computer-guided enzyme engineering of PET hydrolase mutants towards improved PET affinity. [PDF]

BMC Biotechnol
Balola A, Ferreira S, Souza CS, Lousa D, Correia J, Soares CM, Rocha I.   +6 more
europepmc   +1 more source

Direct Enzyme Engineering of B Family DNA Polymerases for Biotechnological Approaches. [PDF]

Bioengineering (Basel), 2023
Kuznetsova AA, Kuznetsov NA.
europepmc   +1 more source