Results 151 to 160 of about 365,104 (302)

Enzyme Engineering for Lipids [PDF]

Lipids (edible fats and oils, phospholipids and glycolipids, etc) are one of major important food resources, in addition to carbohydrate (starch, sugar, etc.) and protein resources. Edible fats and oils are produced mostly from agricultural products such
YAMANE, Tsuneo
core  

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

Machine Learning-Supported Enzyme Engineering toward Improved CO₂-Fixation of Glycolyl-CoA Carboxylase. [PDF]

ACS Synth Biol, 2023
Marchal DG, Schulz L, Schuster I, Ivanovska J, Paczia N, Prinz S, Zarzycki J, Erb TJ.   +7 more
europepmc   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

Synzymes: The Future of Modern Enzyme Engineering. [PDF]

Appl Biochem Biotechnol
Palabiyik AA.
europepmc   +1 more source

Ultrahigh-Throughput Enzyme Engineering and Discovery in <i>In Vitro</i> Compartments. [PDF]

Chem Rev, 2023
Gantz M, Neun S, Medcalf EJ, van Vliet LD, Hollfelder F.   +4 more
europepmc   +1 more source

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

FEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong, Yuhei Hosokawa, Lars Oliver Essen, Manuel Maestre‐Reyna   +3 more
wiley   +1 more source

Enzyme engineering [PDF]

Conference on Enzyme Engineering, Weetall, Howard H., International Enzyme Engineering Conference   +2 more
core   +2 more sources

AI-Driven Enzyme Engineering: Emerging Models and Next-Generation Biotechnological Applications. [PDF]

Molecules
Khan MF, Khan MT.
europepmc   +1 more source

Data-driven enzyme engineering to identify function-enhancing enzymes. [PDF]

Protein Eng Des Sel, 2023
Jiang Y, Ran X, Yang ZJ.
europepmc   +1 more source