Results 61 to 70 of about 365,104 (302)

Quantitative and evolutionary global analysis of enzyme reaction mechanisms [PDF]

, 2015
The most widely used classification system describing enzyme-catalysed reactions is the Enzyme Commission (EC) number. Understanding enzyme function is important for both fundamental scientific and pharmaceutical reasons.
Nath, Neetika
core  

Antimicrobial potential of the combination of fulvic acid and Trichoderma asperellum against rice pathogens

Biological Control
In this study, fluvic acid was prepared from sludge waste. The prepared fulvic acid had almost the same chemical structure as the standard compound expect that it contained a slightly more functional groups, which increased stability and biological ...
Xinyi Hou, Daizong Cui, Jinming Yang, Zhenghao Fang, Min Zhao   +4 more
doaj   +1 more source

Tri©DB: an integrated platform of knowledgebase and reporting system for cancer precision medicine

Journal of Translational Medicine, 2023
Background With the development of cancer precision medicine, a huge amount of high-dimensional cancer information has rapidly accumulated regarding gene alterations, diseases, therapeutic interventions and various annotations.
Wei Jiang, Peng-Ying Wang, Qi Zhou, Qiu-Tong Lin, Yao Yao, Xun Huang, Xiaoming Tan, Shihui Yang, Weicai Ye, Yuedong Yang, Yun-Juan Bao   +10 more
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Microenvironment Engineering of Nanopore for Enzyme Accommodation [PDF]

, 2013
Microenvironment Engineering of Nanopore for Enzyme ...
刘佳, 杨启华, 李灿
core  

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

A Novel Histidinol Phosphate Phosphatase, Catalyzing the Penulimate Step of the Histidine Biosynthesis Pathway, from a Hyperthermophilic Archaeon Thermococcus onnurineus NA1 [PDF]

, 2007
The entire gene cluster encoding enzymes involved in the histidine biosynthesis was analyzed in the complete genome of the hyperthermophilic archaeon Thermococcus onnurineus NA1 and it was found that an essential gene to encode the histidinol phosphate ...
이정현, 강성균, 조요나, 이현숙   +3 more
core  

Metabolic engineering approaches for the biosynthesis of antibiotics

Microbial Cell Factories
Background Antibiotics have been saving countless lives from deadly infectious diseases, which we now often take for granted. However, we are currently witnessing a significant rise in the emergence of multidrug-resistant (MDR) bacteria, making these ...
Geunsoo Yook, Jiwoo Nam, Yeonseo Jo, Hyunji Yoon, Dongsoo Yang   +4 more
doaj   +1 more source

Engineering Pichia pastoris with surface-display minicellulosomes for carboxymethyl cellulose hydrolysis and ethanol production

Biotechnology for Biofuels, 2020
Backgrounds Engineering yeast as a consolidated bioprocessing (CBP) microorganism by surface assembly of cellulosomes has been aggressively utilized for cellulosic ethanol production.
Ce Dong, Jie Qiao, Xinping Wang, Wenli Sun, Lixia Chen, Shuntang Li, Ke Wu, Lixin Ma, Yi Liu   +8 more
doaj   +1 more source

Enzyme Engineering for In Situ Immobilization [PDF]

Molecules, 2016
Enzymes are used as biocatalysts in a vast range of industrial applications. Immobilization of enzymes to solid supports or their self-assembly into insoluble particles enhances their applicability by strongly improving properties such as stability in changing environments, re-usability and applicability in continuous biocatalytic processes.
Rehm, Fabian BH, Chen, Shuxiong, Rehm, Bernd HA   +2 more
openaire   +4 more sources