Results 61 to 70 of about 6,124,915 (260)

Natural Compounds and Health Benefits of Ganoderma capense

Molecules
Ganoderma capense, a member of the Ganoderma genus within the Polyporaceae family, has long been recognized for its high nutritional value and extensive use in traditional medicine.
Longshi Liu, Xinge Shi, Longkang Jia, Ran Wang, Chengwei Liu   +4 more
doaj   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

FEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav, Bogdan I. Florea, Sebastian Geibel   +2 more
wiley   +1 more source

Biocatalysis, Enzyme Engineering and Biotechnology [PDF]

, 2012
Enzymes are biocatalysts evolved in nature to achieve the speed and coordination of nearly all the chemical reactions that define cellular metabolism necessary to develop and maintain life.
D. Platis, I. A. Axarli, Labrou, N. E., E. G. Chronopoulou, C. Karamitros, Axarli, I. A., Kotzia, G. A., Karamitros, C., N. E. Labrou, Chronopoulou, E. G., Platis, D., G. A. Kotzia   +11 more
core   +1 more source

Enzyme-Mineralized PVASA Hydrogels with Combined Toughness and Strength for Bone Tissue Engineering

, 2023
Enzymatic mineralization is an advanced mineralization method that is often used to enhance the stiffness and strength of hydrogels, but often accompanied by brittle behavior.
Fang Wu (267711), Xinying Wang (436220), Tingting Xu (307597), Guangpeng Zhang (10980699), Jing He (58446), Guolong Meng (1781062), Jun Shu (3955211), Jingwen Zhao (636558)   +7 more
core   +2 more sources

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Microenvironment Engineering of Nanopore for Enzyme Accommodation

, 2013
Microenvironment Engineering of Nanopore for Enzyme ...
刘佳, 杨启华, 李灿
core  

Engineering isoflavone metabolism with an artificial bifunctional enzyme

, 2006
Article on engineering isoflavone metabolism with an artificial bifunctional ...
Dixon, R. A., Tian, Li
core   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

Yellow nutsedge WRI4-like gene improves drought tolerance in Arabidopsis thaliana by promoting cuticular wax biosynthesis

BMC Plant Biology, 2020
Background Cuticular wax plays important role in protecting plants from drought stress. In Arabidopsis WRI4 improves drought tolerance by regulating the biosynthesis of fatty acids and cuticular wax.
Chao Cheng, Shutong Hu, Yun Han, Di Xia, Bang-Lian Huang, Wenhua Wu, Jamshaid Hussain, Xuekun Zhang, Bangquan Huang   +8 more
doaj   +1 more source

Prospecting the protein design landscape

FEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona, Katharina T. Stonig, Jens Meiler, Clara T. Schoeder, Monica L. Fernández‐Quintero   +4 more
wiley   +1 more source