Results 21 to 30 of about 4,881,376 (355)

Alpha-Amylase and Alpha-Glucosidase Enzyme Inhibition and Antioxidant Potential of 3-Oxolupenal and Katononic Acid Isolated from Nuxia oppositifolia

Biomolecules, 2019
Nuxia oppositifolia is traditionally used in diabetes treatment in many Arabian countries; however, scientific evidence is lacking. Hence, the present study explored the antidiabetic and antioxidant activities of the plant extracts and their purified ...
A. Alqahtani, S. Hidayathulla, M. Rehman, Ali A. ElGamal, S. Al-Massarani, V. Razmovski-Naumovski, Mohammed S. Alqahtani, R. E. El Dib, M. Alajmi   +8 more
semanticscholar   +1 more source

Point-of-Care Portable 3D-Printed Multispectral Sensor for Real-Time Enzyme Activity Monitoring in Healthcare Applications

Biosensors, 2023
Absorbance spectroscopy finds many biomedical and physical applications ranging from studying the atomic and molecular details of the analyte to determination of unknown biological species and their concentration or activity in the samples.
Antony Jesuraj, Umer Hassan
doaj   +1 more source

In silico design and synthesis of targeted rutin derivatives as xanthine oxidase inhibitors

BMC Chemistry, 2019
Background Xanthine oxidase is an important enzyme of purine catabolism pathway and has been associated directly in pathogenesis of gout and indirectly in many pathological conditions like cancer, diabetes and metabolic syndrome.
Neelam Malik, Priyanka Dhiman, Anurag Khatkar   +2 more
doaj   +1 more source

Phytochemical content, antioxidant activity, and enzyme inhibition effect of Salvia eriophora Boiss. & Kotschy against acetylcholinesterase, α-amylase, butyrylcholinesterase, and α-glycosidase enzymes.

Journal of food biochemistry, 2019
Many taxa of Salvia genus have been used in herbal beverages, food flavoring, cosmetics, and pharmaceutical industry. In this paper, chemical compounds of Salvia eriophora (S.
E. Bursal, Abdülmelik Aras, Ömer Kılıç, Parham Taslimi, A. Gören, I. Gülçin   +5 more
semanticscholar   +1 more source

Phytochemical profiling, antioxidant, enzyme inhibition and cytotoxic potential of Bougainvillea glabra flowers

Natural Product Research, 2019
In this study, phytochemical composition, antioxidant, enzyme inhibition and cytotoxic activities of methanol and dichloromethane (DCM) extracts of Bougainvillea glabra (B. glabra) flowers were investigated.
Hammad Saleem, T. Htar, R. Naidu, G. Zengin, Irshad Ahmad, N. Ahemad   +5 more
semanticscholar   +1 more source

Inhibition of Human Cathepsins B and L by Caffeic Acid and Its Derivatives

Biomolecules, 2020
Caffeic acid (CA) and its derivatives caffeic acid phenethyl ester (CAPE) and chlorogenic acid (CGA) are phenolic compounds of plant origin with a wide range of biological activities. Here, we identify and characterize their inhibitory properties against
Liza Ulčakar, Marko Novinec
doaj   +1 more source

Enzyme inhibition methods based on Au nanomaterials for rapid detection of organophosphorus pesticides in agricultural and environmental samples: A review

Journal of Advanced Research, 2022
Background: Organophosphorus pesticides (OPs), as insecticides or acaricides, are widely used in agricultural products to ensure agricultural production.
Rongqi Zhai, Ge Chen, Guangyang Liu, Xiaodong Huang, XiaoMin Xu, Lingyun Li, Yanguo Zhang, Jing Wang, Maojun Jin, Donghui Xu, A.M. Abd El-Aty   +10 more
doaj   +1 more source

Hydrazones of 4-(Trifluoromethyl)benzohydrazide as New Inhibitors of Acetyl- and Butyrylcholinesterase

Molecules, 2021
Based on the broad spectrum of biological activity of hydrazide–hydrazones, trifluoromethyl compounds, and clinical usage of cholinesterase inhibitors, we investigated hydrazones obtained from 4-(trifluoromethyl)benzohydrazide and various benzaldehydes ...
Martin Krátký, Katarína Svrčková, Quynh Anh Vu, Šárka Štěpánková, Jarmila Vinšová   +4 more
doaj   +1 more source

Assessment of Enzyme Inhibition: A Review with Examples from the Development of Monoamine Oxidase and Cholinesterase Inhibitory Drugs

Molecules, 2017
The actions of many drugs involve enzyme inhibition. This is exemplified by the inhibitors of monoamine oxidases (MAO) and the cholinsterases (ChE) that have been used for several pharmacological purposes.
R. Ramsay, K. Tipton
semanticscholar   +1 more source

Comparing enzyme activity modifier equations through the development of global data fitting templates in Excel [PDF]

PeerJ, 2018
The classical way of defining enzyme inhibition has obscured the distinction between inhibitory effect and the inhibitor binding constant. This article examines the relationship between the simple binding curve used to define biomolecular interactions ...
Ryan Walsh
doaj   +2 more sources