Results 31 to 40 of about 355,555 (310)
Enzyme-Catalyzed Kinetic Resolution of Chiral Precursors to Antiviral Prodrugs [PDF]
Biochemistry, 2019 Nucleoside analogues are among the most common medications given for the treatment of viral infections and cancers. The therapeutic effectiveness of nucleoside analogues can be dramatically improved by phosphorylation. The ProTide approach was developed using a phosphorylated nucleoside that is masked by esterification with an amino acid and phenol ...
Dao Feng Xiang +4 more
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Biogenesis of mitochondrial c-type cytochromes [PDF]
, 1990 Cytochromesc andc 1 are essential components of the mitochondrial respiratory chain. In both cytochromes the heme group is covalently linked to the polypeptide chain via thioether bridges. The location of the two cytochromes is in the intermembrane space;
Gonzales, Daniel H., Neupert, Walter
core +2 more sources
Enzyme-triggered Radical Reactions: Another Approach For Tin-free Radical Chemistry
CHIMIA, 2012 The system laccase/mediator/dioxygen is able to trigger radical reactions with radical precursors which are not natural substrates of this enzyme.
Ibrahima Cissokho +5 more
doaj +1 more source
Substrate- and species-specific processing enzymes for chloroplast precursor proteins [PDF]
Biochemical Journal, 1994 Using different precursors of chloroplast proteins and stromal extracts from both Chlamydomonas reinhardii and pea chloroplasts, we analysed the specificity of stroma-localized processing peptidases. By gel filtration of a stromal extract from isolated Chlamydomonas chloroplasts, fractions could be separated containing enzymic activities for processing
Q, Su, A, Boschetti
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HS1BP3 negatively regulates autophagy by modulation of phosphatidic acid levels
Nature Communications, 2016 Autophagy must be tightly controlled at each step of the process. Here the authors show that HS1BP3 binds phosphatidic acid (PA) at autophagosome precursors and negatively regulates autophagosome formation by modulating the activity and localization of ...
Petter Holland +15 more
doaj +1 more source
Results in Chemistry, 2023 β-Glucosidases (BGLs) are key enzymes for the hydrolysis of glycosidic aroma precursors of wines. However, BGLs produced by oenological yeasts are often inactive or unstable at typical wine pH values.
Stefani de Ovalle +2 more
doaj +1 more source
Functional analysis of the Lactococcus lactis galU and galE genes and their impact on sugar nucleotide and exopolysaccharide biosynthesis [PDF]
, 2001 We studied the UDP-glucose pyrophosphorylase (galU) and UDP-galactose epimerase (galE) genes of Lactococcus lactis MG1363 to investigate their involvement in biosynthesis of UDP-glucose and UDP-galactose, which are precursors of glucose- and galactose ...
Boels, I.C. +3 more
core +1 more source
Biocatalysis as Useful Tool in Asymmetric Synthesis: An Assessment of Recently Granted Patents (2014–2019) [PDF]
, 2019 The broad interdisciplinary nature of biocatalysis fosters innovation, as different technical fields are interconnected and synergized. A way to depict that innovation is by conducting a survey on patent activities.
Alcántara, Andrés R. +2 more
core +3 more sources
Brazilian Journal of Pharmaceutical Sciences, 2015 The objective of this study was to investigate the formation and synthetic mechanism of related substance G in potassium clavulanate production. The impurity in the potassium clavulanate final product, with a retention time of 13.5 min, was confirmed as ...
Xiaoqing Jin +5 more
doaj +1 more source
Enzymic Synthesis of Lignin Precursors [PDF]
European Journal of Biochemistry, 1979 Isoenzyme 2 of cinnamyl‐alcohol dehydrogenase from soybean suspension cultures was purified about 3800‐fold to apparent homogeneity by an improved purification procedure involving biospecific elution of the enzyme from a NADP+‐agarose column. On sodium dodecylsulfate gels the dehydrogenase showed only one protein band with Mr 40000 ± 500.The enzyme is ...
D, Wyrambik, H, Grisebach
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