Results 171 to 180 of about 3,216,786 (362)

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

Molecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck, Nele De Meulenaere, Thomas Vanpoucke, Joe Ibrahim, Dieter Peeters, Suresh Krishan Yogeswaran, Wen Wen, Paul Van Schil, Jeroen M. H. Hendriks, Jo Raskin, Jan van Meerbeeck, Guy Van Camp, Ken Op de Beeck   +12 more
wiley   +1 more source

Improvement of enzyme-linked immunosorbent assay for the multicolor detection of biomarkers

, 2016
Chao Li, Yucai Yang, Dan Wu, Tianqi Li, Yongmei Yin, Genxi Li   +5 more
openalex   +2 more sources

Bound Substrate in the Structure of Cyanobacterial Branching Enzyme Supports a New Mechanistic Model [PDF]

, 2017
Mari Hayashi, Ryuichiro Suzuki, Christophe Colleoni, Steven Ball, Naoko Fujita, Eiji Suzuki   +5 more
openalex   +1 more source

Single molecule analysis indicates stimulation of MUTYH by UV-DDB through enzyme turnover [PDF]

, 2021
Sunbok Jang, Matthew A. Schaich, Cindy Khuu, Brittani L Schnable, Chandrima Majumdar, Simon C. Watkins, Sheila S. David, Bennett Van Houten   +7 more
openalex   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Enzyme-Catalyzed Inverse-Electron Demand Diels–Alder Reaction in the Biosynthesis of Antifungal Ilicicolin H

, 2019
Zhuan Zhang, Cooper S. Jamieson, Yi‐Lei Zhao, Dehai Li, M. Ohashi, K. N. Houk, Yi Tang   +6 more
openalex   +2 more sources

Next‐generation proteomics improves lung cancer risk prediction

Molecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj, Clara Frick, Ben Schöttker, Bernd Holleczek, Hermann Brenner   +4 more
wiley   +1 more source

Nitric oxide mitigates salt stress effects of pepper seedlings by altering nutrient uptake, enzyme activity and osmolyte accumulation

, 2019
Mostafakamal Shams, Melek Ekinci, Selda Örs, Metin Turan, Güleray Ağar, Raziye Kul, Ertan Yıldırım   +6 more
openalex   +2 more sources

Insecticidal and Enzyme Inhibition Activities of Leaf/Bark Extracts, Fractions, Seed Oil and Isolated Compounds from Triadica sebifera (L.) Small against Aphis craccivora Koch [PDF]

, 2022
Shudh Kirti Dolma, Prithvi Pal Singh, S. G. Eswara Reddy   +2 more
openalex   +1 more source

Subcellular localization of pituitary enzymes [PDF]

A cytochemical procedure is reported for identifying subcellular sites of enzymes hydrolyzing beta-naphthylamine substrates, and to study the sites of reaction product localization in cells of various tissues.
Smith, R. E.
core   +1 more source