Results 61 to 70 of about 5,034,587 (402)

The MetaCyc database of metabolic pathways and enzymes

open access: yesNucleic Acids Res., 2017
MetaCyc (https://MetaCyc.org) is a comprehensive reference database of metabolic pathways and enzymes from all domains of life. It contains more than 2570 pathways derived from >54 000 publications, making it the largest curated collection of metabolic ...
R. Caspi   +12 more
semanticscholar   +1 more source

A stepwise emergence of evolution in the RNA world

open access: yesFEBS Letters, EarlyView.
How did biological evolution emerge from chemical reactions? This perspective proposes a gradual scenario of self‐organization among RNA molecules, where catalytic feedback on random mixtures plays the central role. Short oligomers cross‐ligate, and self‐assembly enables heritable variations. An event of template‐externalization marks the transition to
Philippe Nghe
wiley   +1 more source

The Interaction Efficiency of XPD-p44 With Bulky DNA Damages Depends on the Structure of the Damage

open access: yesFrontiers in Cell and Developmental Biology, 2021
The successful elimination of bulky DNA damages via the nucleotide excision repair (NER) system is largely determined by the damage recognition step. This step consists of primary recognition and verification of the damage. The TFIIH helicase XPD plays a
Irina Petruseva   +6 more
doaj   +1 more source

The MetaCyc database of metabolic pathways and enzymes and the BioCyc collection of pathway/genome databases

open access: yesNucleic Acids Res., 2009
The MetaCyc database (MetaCyc.org) is a comprehensive and freely accessible resource for metabolic pathways and enzymes from all domains of life. The pathways in MetaCyc are experimentally determined, small-molecule metabolic pathways and are curated ...
R. Caspi   +17 more
semanticscholar   +1 more source

Enzyme Kinetics at High Enzyme Concentration [PDF]

open access: yesBulletin of Mathematical Biology, 2000
We re-visit previous analyses of the classical Michaelis-Menten substrate-enzyme reaction and, with the aid of the reverse quasi-steady-state assumption, we challenge the approximation d[C]/dt approximately 0 for the basic enzyme reaction at high enzyme concentration.
Schnell, S, Maini, P
openaire   +3 more sources

B cell mechanobiology in health and disease: emerging techniques and insights into therapeutic responses

open access: yesFEBS Letters, EarlyView.
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro   +2 more
wiley   +1 more source

Cyanobacteria: A Promising Source of Antifungal Metabolites

open access: yesMarine Drugs, 2023
Cyanobacteria are a rich source of secondary metabolites, and they have received a great deal of attention due to their applicability in different industrial sectors. Some of these substances are known for their notorious ability to inhibit fungal growth.
Samuel Cavalcante do Amaral   +3 more
doaj   +1 more source

Glycolytic enzymes - novel carbohydrate binding proteins for glycoprotein analysis [PDF]

open access: yes, 2011
•The cloning, expression, purification and characterisation of recombinant prokaryotic glycolytic enzymes •The mutagenesis of prokaryotic glycolytic enzymes to generate novel recombinant carbohydrate binding proteins •The characterisation of the ...
Clarke, Paul A.   +3 more
core  

Transiently Transfected Purine Biosynthetic Enzymes Form Stress Bodies [PDF]

open access: yes, 2013
It has been hypothesized that components of enzymatic pathways might organize into intracellular assemblies to improve their catalytic efficiency or lead to coordinate regulation.
Cook, Lindsey   +5 more
core   +4 more sources

Industrial Applications of Enzymes: Recent Advances, Techniques, and Outlooks

open access: yesCatalysts, 2018
Enzymes as industrial biocatalysts offer numerous advantages over traditional chemical processes with respect to sustainability and process efficiency. Enzyme catalysis has been scaled up for commercial processes in the pharmaceutical, food and beverage ...
Jordan M. Chapman, A. Ismail, C. Dinu
semanticscholar   +1 more source

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