Results 11 to 20 of about 198,261 (297)

Elevated eosinophil level predicted long time to next treatment in relapsed or refractory myeloma patients treated with lenalidomide

Cancer Medicine, 2020
Lenalidomide is an immunomodulatory drug that is administered commonly in patients with relapsed or refractory multiple myeloma (RRMM). Eosinophils have immunological functions, for instance, in allergic diseases and asthma. The purpose of this study was
Kazuhito Suzuki, Kaichi Nishiwaki, Tadahiro Gunji, Mitsuji Katori, Hidekazu Masuoka, Shingo Yano   +5 more
doaj   +1 more source

Impacts of lipid-related metabolites, adiposity, and genetic background on blood eosinophil counts: the Nagahama study

Scientific Reports, 2021
Blood eosinophil count is a useful measure in asthma or COPD management. Recent epidemiological studies revealed that body mass index (BMI) is positively associated with eosinophil counts.
Kenta Nishi, Hisako Matsumoto, Noriyuki Tashima, Satoru Terada, Natsuko Nomura, Mariko Kogo, Chie Morimoto, Hironobu Sunadome, Tadao Nagasaki, Tsuyoshi Oguma, Yoshinari Nakatsuka, Kimihiko Murase, Takahisa Kawaguchi, Yasuharu Tabara, Kazuhiro Sonomura, Fumihiko Matsuda, Kazuo Chin, Toyohiro Hirai   +17 more
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Recent advances in understanding eosinophil biology [version 1; referees: 2 approved]

F1000Research, 2017
With the advent of novel therapies targeting eosinophils, there has been renewed interest in understanding the basic biology of this unique cell. In this context, murine models and human studies have continued to highlight the role of the eosinophil in ...
Amy Klion
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Transcription Factors in Eosinophil Development and As Therapeutic Targets

Frontiers in Medicine, 2017
Dynamic gene expression is a major regulatory mechanism that directs hematopoietic cell fate and differentiation, including eosinophil lineage commitment and eosinophil differentiation. Though GATA-1 is well established as a critical transcription factor
Patricia C. Fulkerson
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Butyrate ameliorates allergic airway inflammation by limiting eosinophil trafficking and survival.

Journal of Allergy and Clinical Immunology, 2019
BACKGROUND Lung eosinophilia is a hallmark of asthma, and eosinophils are believed to play a crucial role in the pathogenesis of allergic inflammatory diseases.
A. Theiler, T. Bärnthaler, W. Platzer, G. Richtig, Miriam Peinhaupt, S. Rittchen, J. Kargl, T. Ulven, L. Marsh, G. Marsche, R. Schuligoi, E. Sturm, A. Heinemann   +12 more
semanticscholar   +1 more source

Skin Eosinophil Counts in Bullous Pemphigoid as a Prognostic Factor for Disease Severity and Treatment Response

Acta Dermato-Venereologica, 2023
Dermal infiltration of eosinophils and eosinophilic spongiosis are prominent features of bullous pemphigoid lesions. Although several observations support the pathogenic role of eosinophils in bullous pemphigoid, few studies have examined the impact of ...
Sharon Baum, Maya Engler Markowitz, Anna Lyakhovitsky, Rotem Gershon, Hannah Aviv, Zvi Segal, Aviv Barzilai   +6 more
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Eosinophil-platelet interactions promote atherosclerosis and stabilize thrombosis by eosinophil extracellular traps.

Blood, 2019
Clinical observations implicate a role of eosinophils in cardiovascular diseases, because markers of eosinophils activation are elevated in atherosclerosis and thrombosis.
Charlotte Marx, Julia Novotny, Danby Salbeck, K. Zellner, Leo Nicolai, Kami Pekayvaz, B. Kilani, Sven Stockhausen, Niklas Bürgener, D. Kupka, T. Stocker, L. Weckbach, J. Pircher, M. Moser, M. Joner, W. Desmet, T. Adriaenssens, F. Neumann, A. Gershlick, J. T. ten Berg, M. Lorenz, K. Stark   +21 more
semanticscholar   +1 more source

CD3−CD4+ lymphoid variant of hypereosinophilic syndrome: nodal and extranodal histopathological and immunophenotypic features of a peripheral indolent clonal T-cell lymphoproliferative disorder

Haematologica, 2015
The CD3−CD4+ lymphoid variant of hypereosinophilic syndrome is characterized by hypereosinophilia and clonal circulating CD3−CD4+ T cells. Peripheral T-cell lymphoma has been described during this disease course, and we observed in our cohort of 23 ...
Guillaume Lefèvre, Marie-Christine Copin, Christophe Roumier, Hélène Aubert, Martine Avenel-Audran, Nathalie Grardel, Stéphanie Poulain, Delphine Staumont-Sallé, Julien Seneschal, Gilles Salles, Kamel Ghomari, Louis Terriou, Christian Leclech, Chafika Morati-Hafsaoui, Franck Morschhauser, Olivier Lambotte, Félix Ackerman, Jacques Trauet, Sandrine Geffroy, Florent Dumezy, Monique Capron, Catherine Roche-Lestienne, Alain Taieb, Pierre-Yves Hatron, Sylvain Dubucquoi, Eric Hachulla, Lionel Prin, Myriam Labalette, David Launay, Claude Preudhomme, Jean-Emmanuel Kahn   +30 more
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Blood eosinophil count thresholds and exacerbations in patients with chronic obstructive pulmonary disease

Journal of Allergy and Clinical Immunology, 2018
Background: Eosinophilic airway inflammation in patients with chronic obstructive pulmonary disease (COPD) is associated with exacerbations and responsivity to steroids, suggesting potential shared mechanisms with eosinophilic asthma.
J. Yun, Andrew Lamb, R. Chase, Dave Singh, M. Parker, A. Saferali, J. Vestbo, R. Tal-Singer, P. Castaldi, E. Silverman, C. Hersh, J. Crapo, B. Make, E. Regan, Terri L Beaty, F. Begum, R. Busch, M. Cho, D. Demeo, A. Boueiz, M. Foreman, Eitan Halper-Stromberg, N. Hansel, M. Hardin, L. Hayden, J. Hetmanski, B. Hobbs, J. Hokanson, N. Laird, C. Lange, S. Lutz, Merry-Lynn N. McDonald, D. Qiao, Stephanie A. Santorico, E. Wan, Sungho Won, M. Al Qaisi, H. Coxson, T. Gray, M. Han, E. Hoffman, S. Humphries, F. Jacobson, P. Judy, Ella A. Kazerooni, A. Kluiber, D. Lynch, John D. Newell, J. Ross, R. Estépar, Joyce D. Schroeder, J. Sieren, Douglas S Stinson, B. Stoel, J. Tschirren, E. V. van Beek, B. van Ginneken, E. V. van Rikxoort, G. Washko, R. Jensen, D. Everett, J. Crooks, Camille M. Moore, M. Strand, C. Wilson, J. Hughes, G. Kinney, K. Pratte, K. Young, J. Curtis, C. Martinez, P. Pernicano, N. Hanania, P. Alapat, Mustafa A. Atik, V. Bandi, A. Boriek, K. Guntupalli, E. Guy, A. Nachiappan, A. Parulekar, C. Hersh, G. Barr, J. Austin, B. D’souza, G. Pearson, A. Rozenshtein, B. Thomashow, N. MacIntyre, Page H. McAdams, L. Washington, C. Mcevoy, J. Tashjian, R. Wise, R. Brown, K. Horton, A. Lambert, N. Putcha, R. Casaburi, A. Adami, M. Budoff, Hans Fischer, J. Porszasz, H. Rossiter, W. Stringer, A. Sharafkhaneh, Charlie Lan, C. Wendt, B. Bell, E. Berkowitz, G. Westney, R. Bowler, R. Rosiello, D. Pace, G. Criner, D. Ciccolella, F. Cordova, C. Dass, G. D'Alonzo, P. Desai, M. Jacobs, S. Kelsen, V. Kim, J. Mamary, N. Marchetti, A. Satti, K. Shenoy, R. Steiner, A. Swift, I. Swift, M. Vega‐Sanchez, M. Dransfield, W. Bailey, S. Bhatt, A. Iyer, H. Nath, Michael J. Wells, J. Ramsdell, P. Friedman, Xavier Soler, A. Yen, A. Comellas, John D. Newell, B. Thompson, Ella A. Kazerooni, J. Billings, Abbie Begnaud, T. Allen, F. Sciurba, J. Bon, D. Chandra, C. Fuhrman, J. Weissfeld, A. Anzueto, S. Adams, Diego Maselli‐Caceres, M. E. Ruiz, Y. Ivanov, K. Kostov, J. Bourbeau, M. Fitzgerald, P. Hernandez, K. Killian, R. Levy, F. Maltais, D. O'Donnell, J. Křepelka, J. Vestbo, E. Wouters, D. Quinn, P. Bakke, M. Košnik, A. Agustí, J. Sauleda, P. de Mallorca, Y. Feschenko, V. Gavrisyuk, Yashina L. Kiev, N. Monogarova, P. Calverley, D. Lomas, W. Macnee, D. Singh, J. Wedzicha, A. Anzueto, S. Braman, R. Casaburi, B. Celli, G. Giessel, M. Gotfried, G. Greenwald, N. Hanania, D. Mahler, B. Make, S. Rennard, C. Rochester, P. Scanlon, D. Schuller, F. Sciurba, A. Sharafkhaneh, T. Siler, E. Silverman, A. Wanner, R. Wise, R. Zuwallack, H. Coxson, C. Crim, L. Edwards, T. Singer, J. Yates, B. Miller, R. Tal-Singer   +211 more
semanticscholar   +1 more source

Elevated Systemic Levels of Eosinophil, Neutrophil, and Mast Cell Granular Proteins in Strongyloides Stercoralis Infection that Diminish following Treatment

Frontiers in Immunology, 2018
Infection with the helminth parasite Strongyloides stercoralis (Ss) is commonly clinically asymptomatic that is often accompanied by peripheral eosinophilia.
Anuradha Rajamanickam, Saravanan Munisankar, Yukthi Bhootra, Chandra Kumar Dolla, Thomas B. Nutman, Subash Babu, Subash Babu   +6 more
doaj   +1 more source