Results 21 to 30 of about 24,045 (247)
Frontiers in Immunology, 2023 BackgroundA growing number of research strongly suggest that metabolic syndrome and dyslipidemia contribute to the establishment of a pro-inflammatory state in asthma, according to accumulating data.
Jun Wen +4 more
doaj +1 more source
Evaluation of exacerbations and blood eosinophils in UK and US COPD populations
Respiratory Research, 2019 Background Blood eosinophil counts and history of exacerbations have been proposed as predictors of patients with chronic obstructive pulmonary disease (COPD) who may benefit from triple therapy (inhaled corticosteroid, long-acting β2-agonist and long ...
Claus F. Vogelmeier +8 more
doaj +1 more source
Natural killer cells induce eosinophil activation and apoptosis.
PLoS ONE, 2014 Eosinophils are potent inflammatory cells with numerous immune functions, including antigen presentation and exacerbation of inflammatory responses through their capacity to release a range of largely preformed cytokines and lipid mediators. Thus, timely
Ali Awad +6 more
doaj +1 more source
Allergy, 2005 Eosinophilic pneumonias (EP) encompass a wide spectrum of lung diseases characterized by peripheral blood eosinophilia (>1 × 109 eosinophils/l) and/or alveolar eosinophilia (>25%). Blood eosinophilia may be lacking, as in the early phase of idiopathic acute EP, or in patients already taking oral corticosteroids.
Cottin, Vincent, Cordier, Jean-François
openaire +4 more sources
Metformin: A potential adjunct for treatment of systemic mastocytosis
Journal of Allergy and Clinical Immunology: GlobalBackground: Systemic mastocytosis (SM) is a clonal disorder of mast cells in which the KIT Asp816Val mutation can be detected not only in mature mast cells but also in the hematopoietic stem cell and in non–mast cell lineages.
Joseph H. Butterfield, MD +1 more
doaj +1 more source
Esophageal Squamous Cell Carcinoma with Marked Eosinophil Infiltration
Case Reports in Gastroenterology, 2011 We report a case of esophageal squamous cell carcinoma (SCC) with marked eosinophil infiltration which was identified postoperatively in the esophageal wall in areas not surrounding the SCC.
Minoru Fukuchi +8 more
doaj +1 more source
Eosinophilic esophagitis [PDF]
Canadian Medical Association Journal, 2018 Eosinophilic esophagitis (EoE) is an atopic condition of the esophagus that has become increasingly recognized over the last 15 years. Diagnosis of the disorder is dependent on the patient’s clinical manifestations, and must be confirmed by histologic findings on esophageal mucosal biopsies.
Thurarshen, Jeyalingam, Samir C, Grover
openaire +7 more sources
FEBS Open Bio, EarlyView.Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu +5 more
wiley +1 more source
Nationwide Survey of Atopic Myelitis and Plexin D1‐Immunoglobulin G‐Related Pain
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To elucidate the features of plexin D1‐immunoglobulin (Ig)G‐associated neuropathic pain and its relationship to atopic myelitis (AM) in a nationwide Japanese survey. Methods A preliminary survey questionnaire was sent to 1574 selected departments (neurology and pediatrics/pediatric neurology) to explore the numbers of AM and plexin ...
Jun‐ichi Kira +10 more
wiley +1 more source
Frontiers in Pediatrics, 2021 The relationship between eosinophils/basophils and allergic sensitization is not clear in pediatric adenotonsillar hypertrophy (ATH). The objective of this study is to investigate the relationship between eosinophil/basophil counts and peripheral ...
Juanjuan Zou +7 more
doaj +1 more source