mTOR complexes differentially orchestrates eosinophil development in allergy
Scientific Reports, 2018 Eosinophil infiltration is considered a hallmark in allergic airway inflammation, and the blockade of eosinophil differentiation may be an effective approach for treating eosinophil-related disorders.
Chen Zhu +14 more
doaj +1 more source
Evaluation of exacerbations and blood eosinophils in UK and US COPD populations
Respiratory Research, 2019 Background Blood eosinophil counts and history of exacerbations have been proposed as predictors of patients with chronic obstructive pulmonary disease (COPD) who may benefit from triple therapy (inhaled corticosteroid, long-acting β2-agonist and long ...
Claus F. Vogelmeier +8 more
doaj +1 more source
Prevalence of asthma and COPD and blood eosinophil count in a middle-aged Belgian population [PDF]
, 2019 Various phenotypes exist in asthma and Chronic Obstructive Pulmonary Disease (COPD). These are important to identify in order to guide treatment decisions.
Brusselle, Guy +4 more
core +1 more source
Machine learning approach for biopsy-based identification of eosinophilic esophagitis reveals importance of global features [PDF]
arXiv, 2021 Goal: Eosinophilic esophagitis (EoE) is an allergic inflammatory condition characterized by eosinophil accumulation in the esophageal mucosa. EoE diagnosis includes a manual assessment of eosinophil levels in mucosal biopsies - a time-consuming, laborious task that is difficult to standardize. One of the main challenges in automating this process, like
arxiv
Allergy, 2005 Eosinophilic pneumonias (EP) encompass a wide spectrum of lung diseases characterized by peripheral blood eosinophilia (>1 × 109 eosinophils/l) and/or alveolar eosinophilia (>25%). Blood eosinophilia may be lacking, as in the early phase of idiopathic acute EP, or in patients already taking oral corticosteroids.
Romain Lazor +2 more
openaire +5 more sources
Esophageal Squamous Cell Carcinoma with Marked Eosinophil Infiltration
Case Reports in Gastroenterology, 2011 We report a case of esophageal squamous cell carcinoma (SCC) with marked eosinophil infiltration which was identified postoperatively in the esophageal wall in areas not surrounding the SCC.
Minoru Fukuchi +8 more
doaj +1 more source
Deep Learning-Based Open Source Toolkit for Eosinophil Detection in Pediatric Eosinophilic Esophagitis [PDF]
arXiv, 2023 Eosinophilic Esophagitis (EoE) is a chronic, immune/antigen-mediated esophageal disease, characterized by symptoms related to esophageal dysfunction and histological evidence of eosinophil-dominant inflammation. Owing to the intricate microscopic representation of EoE in imaging, current methodologies which depend on manual identification are not only ...
arxiv
Use of Machine Learning and Artificial Intelligence to predict SARS-CoV-2 infection from Full Blood Counts in a population [PDF]
International Immunopharmacology, Volume 86,2020,106705,, 2020 Since December 2019 the novel coronavirus SARS-CoV-2 has been identified as the cause of the pandemic COVID-19. Early symptoms overlap with other common conditions such as common cold and Influenza, making early screening and diagnosis are crucial goals for health practitioners.
arxiv +1 more source
Frontiers in Immunology, 2021 Background and PurposeBlood eosinophil counts are thought to be associated with atherosclerosis in acute ischemic stroke (AIS) and AIS severity. We aimed to investigate 1): the temporal profile of eosinophil in AIS patients treated with recombinant ...
Dehao Yang +21 more
doaj +1 more source
CCR8 leads to eosinophil migration and regulates neutrophil migration in murine allergic enteritis [PDF]
, 2019 Allergic enteritis (AE) is a gastrointestinal form of food allergy. This study aimed to elucidate cellular and molecular mechanisms of AE using a murine model. To induce AE, BALB/c wild type (WT) mice received intraperitoneal sensitization with ovalbumin
Blanco Pérez, Frank +14 more
core +1 more source