Results 51 to 60 of about 186,812 (342)

Eosinophil Granule Proteins: Form and Function

Journal of Biological Chemistry, 2014
Experimental and clinical data strongly support a role for the eosinophil in the pathogenesis of asthma, allergic and parasitic diseases, and hypereosinophilic syndromes, in addition to more recently identified immunomodulatory roles in shaping innate ...
K. Ravi Acharya, Steven J. Ackerman
semanticscholar   +1 more source

A Hierarchically Structured, Stretchable, Anti‐Biofouling Encapsulation for Biodegradable Electronics

Advanced Healthcare Materials, EarlyView.
A soft, stretchable, anti‐biofouling encapsulant is developed by integrating organosilicon nanowire networks with microstructured biodegradable elastomers. The hierarchical surface exhibits superhydrophobicity and enhances water barrier properties by 420% over pristine polymers, while preserving mechanical integrity.
Won Bae Han, Sungkeun Han, Gwan‐Jin Ko, Ulziituya Batjargal, Wonjun Jang, Venkata Ramesh Naganaboina, Han‐Jun Kim, Suk‐Won Hwang   +7 more
wiley   +1 more source

Gentamicin‐Loaded Carbonate Apatite with Dual Antibacterial and Osteogenic Functions for Combating Surgical Site Infections

Advanced Healthcare Materials, EarlyView.
A bone substitute with gentamicin physically precipitated onto the surface of carbonate apatite exhibits prompt drug release, high bactericidal activity, and osteogenic capacity. Efficient antibacterial activity mitigates early postoperative neutrophil accumulation, the status of which may serve as a potential parameter for evaluating the antibacterial
Linghao Xiao, Gabriela Laranjeira Abe, Jun‐Ichi Sasaki, Haruaki Kitagawa, Ririko Tsuboi, Tomoki Kohno, Satoshi Imazato   +6 more
wiley   +1 more source

Health care resource utilization and characteristics of patients with eosinophilic asthma in secondary health care in Finland

European Clinical Respiratory Journal, 2018
Background: Eosinophilic airway inflammation is common in asthma patients and appears to be associated with severe exacerbations and loss of asthma control.
Mika J. Mäkelä, Helene Nordahl Christensen, Antti Karlsson, Sarang Rastogi, Kirsi Kettunen   +4 more
doaj   +1 more source

Advances in Bioprinting to Model Immune‐Mediated Skin Diseases

Advanced Healthcare Materials, EarlyView.
This review explores how 3D bioprinting drives innovation in developing in vitro skin models that mimic immune‐mediated diseases. It highlights current technologies, key applications in studying skin pathologies, and emerging challenges. The review points toward future opportunities for improving disease modeling and advancing therapeutic and cosmetic ...
Andrea Ulloa‐Fernández, Marica Markovic, Julia Fernández‐Pérez, Georg Stary, Aleksandr Ovsianikov   +4 more
wiley   +1 more source

Comparing Patient Characteristics, Clinical Outcomes, and Biomarkers of Severe Asthma Patients in Taiwan

Biomedicines, 2021
Purpose: To understand the association between biomarkers and exacerbations of severe asthma in adult patients in Taiwan. Materials and Methods: Demographic, clinical characteristics and biomarkers were retrospectively collected from the medical charts ...
Shih-Lung Cheng, Kuo-Chin Chiu, Hsin-Kuo Ko, Diahn-Warng Perng, Hao-Chien Wang, Chong-Jen Yu, Chau-Chyun Sheu, Sheng-Hao Lin, Ching-Hsiung Lin   +8 more
doaj   +1 more source

The transcription factor XBP1 is selectively required for eosinophil differentiation

Nature Immunology, 2015
The transcription factor XBP1 has been linked to the development of highly secretory tissues such as plasma cells and Paneth cells, yet its function in granulocyte maturation has remained unknown. Here we discovered an unexpectedly selective and absolute
Sarah E. Bettigole, Raphael Lis, S. Adoro, Ann-Hwee Lee, L. Spencer, Peter F. Weller, Laurie H. Glimcher   +6 more
semanticscholar   +1 more source

Mesenchymal Stem Cell‐Derived Apoptotic Micro‐Vesicles Repaired Sciatic Nerve Defect by Regulating Early Inflammatory Microenvironment and Promoting Angiogenesis

Advanced Healthcare Materials, EarlyView.
HUCMSC‐Apo‐mvs enhance peripheral nerve repair by modulating the inflammatory microenvironment (IME), primarily through coordinated actions on three functional cells. They recruit macrophages and promote their polarization from pro‐inflammatory M1 to anti‐inflammatory M2 phenotypes, increasing secretion of IL‐10 and VEGF.
Haolin Liu, Yiben Ouyang, Bo Wang, Xiaochun Zhang, Yanjun Guan, Ruichao He, Yuhui Cui, Junli Wang, Qianru Yao, Yixiao Tan, Xiwei Peng, Xing Xiong, Sice Wang, Dongdong Li, Haofeng Cheng, Tianqi Su, Xiaoyang Fu, Jinjuan Zhao, Mingqian Yu, Yi Wang, Jiang Peng, Yu Wang   +21 more
wiley   +1 more source

Study of serum interleukin 5 level and factors that impact on this level in Iraqi asthmatic children

Biomedical and Biotechnology Research Journal, 2019
Background: Interleukin-5 (IL-5) is a cytokine associated with the cause of several allergic diseases such as asthma due to their function in growth, activation, and maturation of eosinophils and stimulates B-cell growth and increases immunoglobulin E ...
Raghdah Maytham Hameed, Haidar Abdul Amir Najim Abood, Mohanad Mohsin Ahmed, Aqeel Mahdi Hussein   +3 more
doaj   +1 more source

Eosinophil Cytokines, Chemokines, and Growth Factors: Emerging Roles in Immunity

Frontiers in Immunology, 2014
Eosinophils derive from the bone marrow and circulate at low levels in the blood in healthy individuals. These granulated cells preferentially leave the circulation and marginate to tissues, where they are implicated in the regulation of innate and ...
F. Davoine, Paige Lacy
semanticscholar   +1 more source