Results 61 to 70 of about 222,956 (401)
Eosinophils in filarial infections: Inducers of protection or pathology?
Frontiers in Immunology, 2022 Filariae are parasitic roundworms, which can cause debilitating diseases such as lymphatic filariasis and onchocerciasis. Lymphatic filariasis, also known as elephantiasis, and onchocerciasis, commonly referred to as river blindness, can lead to ...
Alexandra Ehrens +5 more
doaj +1 more source
A new formulation of oral viscous budesonide in treating of paediatric eosinophilic oesophagitis: a pilot study [PDF]
, 2017 OBJECTIVES: Oral viscous budesonide is a recent therapeutic option for eosinophilic oesophagitis (EoE) compared with dietary restriction and inhaled steroids.
Amil, D. J. +8 more
core +1 more source
The influence of dipeptidyl peptidase-4 inhibitor on the progression of type B intramural hematoma
Frontiers in Cardiovascular Medicine, 2022 ObjectivesInvestigating whether dipeptidyl peptidase-4 inhibitors (DPP4i) could influence the progression of type B intramural hematoma (IMHB) in patients with diabetes mellitus (DM).Materials and methodsUncomplicated IMHB patients were matched by age ...
Qu Chen, Dandan Jiang, Zhonggui Shan
doaj +1 more source
Th2 and eosinophil responses suppress inflammatory arthritis
Nature Communications, 2016 Th2–eosinophil immune responses are well known for mediating host defence against helminths. Herein we describe a function of Th2–eosinophil responses in counteracting the development of arthritis.
Zhu Chen +8 more
semanticscholar +1 more source
Dupilumab in persistent asthma with elevated eosinophil levels.
New England Journal of Medicine, 2013 BACKGROUND Moderate-to-severe asthma remains poorly treated. We evaluated the efficacy and safety of dupilumab (SAR231893/REGN668), a fully human monoclonal antibody to the alpha subunit of the interleukin-4 receptor, in patients with persistent ...
S. Wenzel +16 more
semanticscholar +2 more sources
Antagonism of cytokine-induced eosinophil accumulation in asthma [PDF]
, 2012 Peer reviewedPublisher ...
Walsh, Garry M.
core +2 more sources
Bidirectional Mast Cell–Eosinophil Interactions in Inflammatory Disorders and Cancer
Frontiers in Medicine, 2017 Human mast cells (MCs) and eosinophils were first described and named by Paul Ehrlich. These cells have distinct myeloid progenitors and differ morphologically, ultrastructurally, immunologically, biochemically, and pharmacologically.
M. Galdiero +5 more
semanticscholar +1 more source
Neutrophil deficiency increases T cell numbers at the site of tissue injury in mice
FEBS Letters, EarlyView.In wild‐type mice, injury or acute inflammation induces neutrophil influx followed by macrophage accumulation. Mcl1ΔMyelo (neutrophil‐deficient) mice lack neutrophils, and in response to muscle injury show fewer macrophages and exhibit strikingly elevated T‐cell numbers, primarily non‐conventional “double‐negative” (DN) αβ and γδ T cells.
Hajnalka Halász +6 more
wiley +1 more source
Nonesophageal Eosinophilic Gastrointestinal Disorders: Clinical Care and Future Directions [PDF]
, 2018 Eosinophilic gastrointestinal disorders are a set of conditions with a wide range of clinical manifestations and treatment modalities. The disorders are suspected to result from an abnormal inflammatory response to allergen(s), and individuals may ...
Gupta, Sandeep K., Naramore, Sara
core +1 more source
FEBS Open Bio, EarlyView.In this research, a rat model of asthma was created using OVA, and polydatin served as an intervention. By inhibiting ferroautophagy mediated by NCOA4 and averting ferroptosis, polydatin has been demonstrated to reduce asthma. This work presents new ideas for investigating the mechanism of polydatin's ability to alleviate asthma, in addition to ...
Wei Li +5 more
wiley +1 more source