Results 41 to 50 of about 10,072 (196)

Impact of Chronic Rhinosinusitis with Nasal Polyposis on IL-12 and IL-8 [PDF]

Iranian Journal of Otorhinolaryngology, 2023
Introduction: The pathophysiology of Chronic Rhinosinusitis is coordinated by distinct inflammatory reactions in different individuals. Inflammatory environments with a predominance of Th2 lymphocytes tend also to be rich in eosinophils.
Jonatas do Amaral, Andrea David, Luciane Mello, Andre Luis Lacerda Bachi, Richard Louis Vogels, Andrew Thamboo, Rogério Pezato   +6 more
doaj   +1 more source

Type 2 Innate Lymphoid Cells in Allergic Disease. [PDF]

, 2013
Type II innate lymphoid cells (ILC2) are a novel population of lineage-negative cells that produce high levels of Th2 cytokines IL-5 and IL-13. ILC2 are found in human respiratory and gastrointestinal tissue as well as in skin.
Doherty, Taylor A, Lund, Sean, Walford, Hannah H   +2 more
core   +2 more sources

Eosinophilic airway inflammation and eosinophilic chronic rhinosinusitis during nivolumab and ipilimumab [PDF]

Respirology Case Reports, 2020
AbstractImmune‐related adverse events (irAEs) are induced by immune checkpoint inhibitors (ICIs) which are administered for many cancers. There are many irAEs such as endocrine abnormalities, interstitial lung disease, and colitis. However, irAEs associated with type 2 (T2) inflammation are less known. We herein report a 71‐year‐old woman who developed
Hirofumi Watanabe, Kazuhiro Asada, Toshihiro Shirai, Hiroko Torii, Koji Yoshimura, Kimihide Kusafuka   +5 more
openaire   +3 more sources

The Burden of Revision Sinonasal Surgery in the UK – Data from the Chronic Rhinosinusitis Epidemiology Study (CRES); a cross sectional study [PDF]

, 2015
Objectives/Hypothesis The aim of this study was to investigate the surgical revision rate in patients with Chronic Rhinosinusitis (CRS) in the UK CRS Epidemiology Study (CRES). Previous evidence from national Sinonasal Audit showed that 1459 CRS patients
Ahmed, Shahzada, Almeyda, Robert, Anari, Shahram, Carrie, Sean, Cathcart, Russell, Clark, Allan, Erskine, Sally, Farboud, Amir, Hobson, Jonathan, Hopkins, Claire, Jervis, Paul, Kara, Naveed, Khalil, Hisham, Kumar, Nirmal, Mansell, Nicholas, Morris, Steve, Panesaar, Jaan, Philpott, Carl, Prinsley, Peter, Ray, Jaydip, Robertson, Alasdair, Salam, Mahmoud, Sunkaraneni, Vishnu   +22 more
core   +3 more sources

Reduced Local Response to Corticosteroids in Eosinophilic Chronic Rhinosinusitis with Asthma

Biomolecules, 2020
Eosinophilic chronic rhinosinusitis (ECRS), a subgroup of chronic rhinosinusitis with nasal polyps, is recognized as a refractory eosinophilic disorder characterized by both upper and lower airway inflammation.
Yoshiki Kobayashi, Akira Kanda, Yasutaka Yun, Dan Van Bui, Kensuke Suzuki, Shunsuke Sawada, Mikiya Asako, Hiroshi Iwai   +7 more
doaj   +1 more source

Anatomic findings in revision endoscopic sinus surgery: Case series and review of contributory factors [PDF]

, 2016
Background: It is recognized that patients who undergo endoscopic sinus surgery (ESS) do not always achieve control of their disease. The causes are multifactorial; variations in surgical practice have been identified as possible factors in refractory ...
Bewick, Jessica, Egro, Francesco M., Javer, Amin R., Masterson, Liam, Philpott, Carl M.   +4 more
core   +1 more source

Alterations of nasal microbiome in eosinophilic chronic rhinosinusitis

Journal of Allergy and Clinical Immunology, 2023
Exposure to microbes may be important in the development of chronic rhinosinusitis (CRS). Dysbiosis of the nasal microbiome is considered to be related to CRS with nasal polyps (CRSwNP). The link between the nasal microbiota and eosinophilic CRSwNP (eCRSwNP) has rarely been studied.The aim of this study was to rigorously characterize nasal dysbiosis in
Yibo, Liang, Runxiang, Xie, Xin, Xiong, Zhanjun, Hu, Xiang, Mao, Xiaoyu, Wang, Jinmei, Zhang, Peiyong, Sun, Zhenzhong, Yue, Wei, Wang, Guimin, Zhang   +10 more
openaire   +2 more sources

Allergic fungal rhinosinusitis infiltrating anterior skull base and clivus. [PDF]

, 2012
Bone erosion and skull base invasion are often suggestive of a malignant mass in paranasal and nasal cavities. Nevertheless, forms of chronic rhinosinusitis, such as allergic fungal rhinosinusitis (AFRS), could mimic malignant features.
A. Deganello, C. Georgalas, F. Ammannati, G. Bianco, G. Mannelli, G. Meccariello, O. Gallo   +6 more
core   +2 more sources

Increased CD69 expression on activated eosinophils in eosinophilic chronic rhinosinusitis correlates with clinical findings

Allergology International, 2020
Background: Eosinophilic chronic rhinosinusitis (ECRS) is a subtype of chronic rhinosinusitis associated with asthma. CD69 is an important marker of activation for eosinophils.
Yasutaka Yun, Akira Kanda, Yoshiki Kobayashi, Dan Van Bui, Kensuke Suzuki, Shunsuke Sawada, Kazuyasu Baba, Masao Yagi, Mikiya Asako, Haruka Okazaki, Hiroki Ikeda, Shigeki Kawamura, Akihiko Nakamura, David Dombrowicz, Koichi Tomoda, Hiroshi Iwai   +15 more
doaj   +1 more source

Eosinophilic granulomatosis with polyangiitis developed after dupilumab administration in patients with eosinophilic chronic rhinosinusitis and asthma: a case report

BMC Pulmonary Medicine, 2023
Background Eosinophilic granulomatosis with polyangiitis (EGPA) is a form of anti-neutrophil cytoplasmic antibody (ANCA) associated vasculitis characterized by eosinophil-rich granulomatous inflammation and small-to-medium vessel vasculitis associated ...
Isao Suzaki, Akihiko Tanaka, Ryo Yanai, Yuki Maruyama, Sawa Kamimura, Kojiro Hirano, Hitome Kobayashi   +6 more
doaj   +1 more source