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The Immunosuppressive Functions of Eosinophils Are Compromised in Patients With Allergic Rhinitis, Particularly Concerning Rab27a Expression [PDF]

open access: yesImmunity, Inflammation and Disease
Background Eosinophils have been acknowledged to be involved in the induction of numerous inflammatory disorders. There is still a lack of knowledge about whether eosinophils play a role in immune regulation.
Yun Liao   +7 more
doaj   +2 more sources

Dermatomyositis with Eosinophils

open access: yesDermatopathology, 2023
Dermatomyositis is an idiopathic inflammatory myopathy that often presents with symmetric proximal skeletal muscle weakness and characteristic skin findings. Typical skin biopsy findings include vacuolar changes of the basal layer, increased dermal mucin,
Isabella I. Sanchez   +4 more
doaj   +3 more sources

Protocol for autofluorescence-driven isolation of human peripheral blood eosinophils [PDF]

open access: yesSTAR Protocols
Summary: Most common techniques for isolating eosinophils utilize CD16-negative selection, neglecting the CD16-positive fraction of eosinophils. Here, we present a protocol for isolating human CD16+ and CD16− eosinophils based on their autofluorescence ...
Tobias Weihrauch   +4 more
doaj   +2 more sources

The Role of Eosinophils in Bullous Pemphigoid: A Developing Model of Eosinophil Pathogenicity in Mucocutaneous Disease

open access: yesFrontiers in Medicine, 2018
Bullous pemphigoid (BP) is an autoimmune blistering disease which carries a significant mortality and morbidity. While historically BP has been characterized as an IgG driven disease mediated by anti-BP180 and BP230 IgG autoantibodies, developments in ...
Kyle T Amber   +2 more
exaly   +3 more sources

Role of Eosinophils in Intestinal Inflammation and Fibrosis in Inflammatory Bowel Disease: An Overlooked Villain?

open access: yesFrontiers in Immunology, 2021
Eosinophils are leukocytes which reside in the gastrointestinal tract under homeostatic conditions, except for the esophagus which is normally devoid of eosinophils.
Lucas Wauters   +2 more
exaly   +3 more sources

Transcriptional Profiling of Mouse Eosinophils Identifies Distinct Gene Signatures Following Cellular Activation

open access: yesFrontiers in Immunology, 2021
Eosinophils are multifunctional, evolutionary conserved leukocytes that are involved in a plethora of responses ranging from regulation of tissue homeostasis to host defense and cancer.
Avishay Dolitzky   +8 more
doaj   +1 more source

Eosinophils in eosinophilic pneumonia [PDF]

open access: yesEuropean Respiratory Journal, 1996
Idiopathic eosinophilic pneumonia (IEP) is an uncom-mon disease of unknown aetiology characterized by theaccumulation of eosinophils in the lung, variable bloodeosinophilia and peripheral opacities on the chest radio-gram. The response to steroid treatment is dramatic butrelapses are frequent, requiring the use of long-termsteroid treatment [1 ...
ALBERA, Carlo, P. GHIO
openaire   +2 more sources

Eosinophils: A Friend or Foe in human health and diseases

open access: yesKidney Diseases, 2022
Since their discovery, around 150 years, eosinophils research has been a field of changing perspective, and new directions are emerging since then. Initially, eosinophils were perceived as terminally-differentiated cytotoxic effector cells.
Madiha Zahra Syeda   +4 more
doaj   +1 more source

Differential regulation of Type 1 and Type 2 mouse eosinophil activation by apoptotic cells

open access: yesFrontiers in Immunology, 2022
Eosinophils are multifunctional, evolutionary conserved leukocytes that are involved in a plethora of responses ranging from regulation of tissue homeostasis, host defense and cancer. Although eosinophils have been studied mostly in the context of Type 2
Avishay Dolitzky   +8 more
doaj   +1 more source

Eosinophils Decrease Pulmonary Metastatic Mammary Tumor Growth

open access: yesFrontiers in Oncology, 2022
Metastatic breast cancer is challenging to effectively treat, highlighting the need for an improved understanding of host factors that influence metastatic tumor cell colonization and growth in distant tissues.
Rachel A. Cederberg   +17 more
doaj   +1 more source

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