Results 1 to 10 of about 234,859 (336)

Eosinophils are important for protection, immunoregulation and pathology during infection with nematode microfilariae. [PDF]

PLoS Pathogens, 2014
Eosinophil responses typify both allergic and parasitic helminth disease. In helminthic disease, the role of eosinophils can be both protective in immune responses and destructive in pathological responses. To investigate whether eosinophils are involved
Emma T Cadman, Katherine A Thysse, Siobhan Bearder, Anita Y N Cheung, Ashleigh C Johnston, James J Lee, Rachel A Lawrence   +6 more
doaj   +4 more sources

Dermatomyositis with Eosinophils [PDF]

Dermatopathology, 2023
Dermatomyositis is an idiopathic inflammatory myopathy that often presents with symmetric proximal skeletal muscle weakness and characteristic skin findings. Typical skin biopsy findings include vacuolar changes of the basal layer, increased dermal mucin,
Isabella I. Sanchez, Henry O. Herrera, Ashley Elsensohn, Bonnie A. Lee, Christina N. Kraus   +4 more
doaj   +4 more sources

Activated eosinophil plays a role in promoting fibrosis in endometriotic lesion [PDF]

Scientific Reports
The fibrosis mechanism in endometriosis is not elucidated. We investigated the role of eosinophil in fibrosis of endometriosis. The endometriotic stromal cells (ESCs) and endometrial epithelial cells (EECs) were subjected to in vitro experiments.
Yosuke Ono, Kota Tanaka, Erina Sato, Masami Ito, Di Zhang, Masako Honda, Tatsuyuki Ogawa, Hikaru Tagaya, Tomohiko Fukuda, Youichi Shinozaki, Kazuyoshi Kato, Schuichi Koizumi, Osamu Yoshino   +12 more
doaj   +2 more sources

High fat diet causes depletion of intestinal eosinophils associated with intestinal permeability. [PDF]

, 2015
The development of intestinal permeability and the penetration of microbial products are key factors associated with the onset of metabolic disease. However, the mechanisms underlying this remain unclear. Here we show that, unlike liver or adipose tissue,
Armando, Aaron M, Costanzo, Anne, Gareau, Melanie G, Jameson, Julie M, Johnson, Andrew MF, Olefsky, Jerrold M, Quehenberger, Oswald   +6 more
core   +18 more sources

The multiple functions and subpopulations of eosinophils in tissues under steady-state and pathological conditions

Allergology International, 2021
Eosinophils not only play a critical role in the pathogenesis of eosinophil-associated diseases, but they also have multiple important biological functions, including the maintenance of homeostasis, host defense against infections, immune regulation ...
Akira Kanda, Yasutaka Yun, Dan Van Bui, Linh Manh Nguyen, Yoshiki Kobayashi, Kensuke Suzuki, Akitoshi Mitani, Shunsuke Sawada, Satoko Hamada, Mikiya Asako, Hiroshi Iwai   +10 more
doaj   +1 more source

Transcriptional Profiling of Mouse Eosinophils Identifies Distinct Gene Signatures Following Cellular Activation

Frontiers in Immunology, 2021
Eosinophils are multifunctional, evolutionary conserved leukocytes that are involved in a plethora of responses ranging from regulation of tissue homeostasis to host defense and cancer.
Avishay Dolitzky, Guy Shapira, Sharon Grisaru-Tal, Inbal Hazut, Shmulik Avlas, Yaara Gordon, Micahl Itan, Noam Shomron, Ariel Munitz   +8 more
doaj   +1 more source

Differential regulation of Type 1 and Type 2 mouse eosinophil activation by apoptotic cells

Frontiers in Immunology, 2022
Eosinophils are multifunctional, evolutionary conserved leukocytes that are involved in a plethora of responses ranging from regulation of tissue homeostasis, host defense and cancer. Although eosinophils have been studied mostly in the context of Type 2
Avishay Dolitzky, Inbal Hazut, Shmulik Avlas, Sharon Grisaru-Tal, Michal Itan, Ilan Zaffran, Francesca Levi-Schaffer, Motti Gerlic, Ariel Munitz   +8 more
doaj   +1 more source

Eosinophils: A Friend or Foe in human health and diseases

Kidney Diseases, 2022
Since their discovery, around 150 years, eosinophils research has been a field of changing perspective, and new directions are emerging since then. Initially, eosinophils were perceived as terminally-differentiated cytotoxic effector cells.
Madiha Zahra Syeda, Tu Hong, Chao Zhang, Songmin Ying, Huahao Shen   +4 more
doaj   +1 more source

Eosinophils Decrease Pulmonary Metastatic Mammary Tumor Growth

Frontiers in Oncology, 2022
Metastatic breast cancer is challenging to effectively treat, highlighting the need for an improved understanding of host factors that influence metastatic tumor cell colonization and growth in distant tissues.
Rachel A. Cederberg, Rachel A. Cederberg, Sarah Elizabeth Franks, Brennan J. Wadsworth, Brennan J. Wadsworth, Alvina So, Lisa R. Decotret, Lisa R. Decotret, Michael G. Hall, Michael G. Hall, Rocky Shi, Rocky Shi, Michael R. Hughes, Kelly M. McNagny, Kelly M. McNagny, Kevin L. Bennewith, Kevin L. Bennewith, Kevin L. Bennewith   +17 more
doaj   +1 more source

The histopathological spectrum of acute generalized exanthematous pustulosis (AGEP) and its differentiation from generalized pustular psoriasis [PDF]

, 2010
Background: Acute generalized exanthematous pustulosis (AGEP) represents a severe, acute, pustular skin reaction that is most often induced by drugs. AGEP can be difficult to differentiate from generalized pustular psoriasis (GPP) both clinically and ...
Austin, Baker, Beylot, Beylot, Britschgi, Burrows, Farber, Friedman, Guevara-Gutierrez, Horn, Iizuka, Kardaun, Katz, Keller, Kingery, Macmillan, Mobini, Muller, Naldi, Roujeau, Roujeau, Schaefer, Schmid, Shelley, Shelley, Sidoroff, Sidoroff, Smith, Spencer, Staughton, Terui, Weedon, Weedon, Yawalkar, Zelickson   +34 more
core   +11 more sources