Results 1 to 10 of about 212,224 (229)

Eosinophils are important for protection, immunoregulation and pathology during infection with nematode microfilariae. [PDF]

open access: yesPLoS Pathogens, 2014
Eosinophil responses typify both allergic and parasitic helminth disease. In helminthic disease, the role of eosinophils can be both protective in immune responses and destructive in pathological responses. To investigate whether eosinophils are involved
Emma T Cadman   +6 more
doaj   +6 more sources

Humanized FcεRI Expressed on Mouse Eosinophils Mediates IgE-Facilitated Eosinophil Antigen Presentation. [PDF]

open access: yesCells
High-affinity IgE receptors (FcεRI) are expressed on human blood eosinophils and may be upregulated on eosinophils at sites of allergic inflammation including atopic dermatitis and allergic asthma.
Wang H, Kinet JP, Weller PF.
europepmc   +2 more sources

Role of Eosinophils in Intestinal Inflammation and Fibrosis in Inflammatory Bowel Disease: An Overlooked Villain?

open access: yesFrontiers in Immunology, 2021
Eosinophils are leukocytes which reside in the gastrointestinal tract under homeostatic conditions, except for the esophagus which is normally devoid of eosinophils.
Lucas Wauters   +2 more
exaly   +3 more sources

The Role of Eosinophils in Bullous Pemphigoid: A Developing Model of Eosinophil Pathogenicity in Mucocutaneous Disease

open access: yesFrontiers in Medicine, 2018
Bullous pemphigoid (BP) is an autoimmune blistering disease which carries a significant mortality and morbidity. While historically BP has been characterized as an IgG driven disease mediated by anti-BP180 and BP230 IgG autoantibodies, developments in ...
Kyle T Amber   +2 more
exaly   +3 more sources

The Immunosuppressive Functions of Eosinophils Are Compromised in Patients With Allergic Rhinitis, Particularly Concerning Rab27a Expression. [PDF]

open access: yesImmun Inflamm Dis
Background Eosinophils have been acknowledged to be involved in the induction of numerous inflammatory disorders. There is still a lack of knowledge about whether eosinophils play a role in immune regulation.
Liao Y   +7 more
europepmc   +2 more sources

Transcriptional Profiling of Mouse Eosinophils Identifies Distinct Gene Signatures Following Cellular Activation

open access: yesFrontiers in Immunology, 2021
Eosinophils are multifunctional, evolutionary conserved leukocytes that are involved in a plethora of responses ranging from regulation of tissue homeostasis to host defense and cancer.
Avishay Dolitzky   +8 more
doaj   +1 more source

Differential regulation of Type 1 and Type 2 mouse eosinophil activation by apoptotic cells

open access: yesFrontiers in Immunology, 2022
Eosinophils are multifunctional, evolutionary conserved leukocytes that are involved in a plethora of responses ranging from regulation of tissue homeostasis, host defense and cancer. Although eosinophils have been studied mostly in the context of Type 2
Avishay Dolitzky   +8 more
doaj   +1 more source

Eosinophils: A Friend or Foe in human health and diseases

open access: yesKidney Diseases, 2022
Since their discovery, around 150 years, eosinophils research has been a field of changing perspective, and new directions are emerging since then. Initially, eosinophils were perceived as terminally-differentiated cytotoxic effector cells.
Madiha Zahra Syeda   +4 more
doaj   +1 more source

Eosinophils Decrease Pulmonary Metastatic Mammary Tumor Growth

open access: yesFrontiers in Oncology, 2022
Metastatic breast cancer is challenging to effectively treat, highlighting the need for an improved understanding of host factors that influence metastatic tumor cell colonization and growth in distant tissues.
Rachel A. Cederberg   +17 more
doaj   +1 more source

A role for eosinophils in the intestinal immunity against infective Ascaris suum larvae [PDF]

open access: yes, 2013
The aim of this study was to explore the mechanisms of resistance against invading Ascaris suum larvae in pigs. Pigs received a low dose of 100 A. suum eggs daily for 14 weeks.
Chiers, Koen   +6 more
core   +9 more sources

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