Results 1 to 10 of about 229,369 (202)
Eosinophils are important for protection, immunoregulation and pathology during infection with nematode microfilariae. [PDF]
PLoS Pathogens, 2014 Eosinophil responses typify both allergic and parasitic helminth disease. In helminthic disease, the role of eosinophils can be both protective in immune responses and destructive in pathological responses. To investigate whether eosinophils are involved
Emma T Cadman +6 more
doaj +4 more sources
Activated eosinophil plays a role in promoting fibrosis in endometriotic lesion [PDF]
Scientific ReportsThe fibrosis mechanism in endometriosis is not elucidated. We investigated the role of eosinophil in fibrosis of endometriosis. The endometriotic stromal cells (ESCs) and endometrial epithelial cells (EECs) were subjected to in vitro experiments.
Yosuke Ono +12 more
doaj +2 more sources
Single-cell RNA-sequencing of circulating eosinophils from asthma patients reveals an inflammatory signature [PDF]
iScienceSummary: Asthma is the most common chronic lung disorder in the United States. While asthma is heterogeneous, blood eosinophils are central to the pathogenesis in most cases.
Kyndal Goss +6 more
doaj +2 more sources
Frontiers in Immunology, 2021 Eosinophils are leukocytes which reside in the gastrointestinal tract under homeostatic conditions, except for the esophagus which is normally devoid of eosinophils.
Lucas Wauters +2 more
exaly +3 more sources
Frontiers in Medicine, 2018 Bullous pemphigoid (BP) is an autoimmune blistering disease which carries a significant mortality and morbidity. While historically BP has been characterized as an IgG driven disease mediated by anti-BP180 and BP230 IgG autoantibodies, developments in ...
Kyle T Amber +2 more
exaly +3 more sources
Frontiers in Immunology, 2021 Eosinophils are multifunctional, evolutionary conserved leukocytes that are involved in a plethora of responses ranging from regulation of tissue homeostasis to host defense and cancer.
Avishay Dolitzky +8 more
doaj +1 more source
High fat diet causes depletion of intestinal eosinophils associated with intestinal permeability. [PDF]
, 2015 The development of intestinal permeability and the penetration of microbial products are key factors associated with the onset of metabolic disease. However, the mechanisms underlying this remain unclear. Here we show that, unlike liver or adipose tissue,
Armando, Aaron M +6 more
core +15 more sources
A role for eosinophils in the intestinal immunity against infective Ascaris suum larvae [PDF]
, 2013 The aim of this study was to explore the mechanisms of resistance against invading Ascaris suum larvae in pigs. Pigs received a low dose of 100 A. suum eggs daily for 14 weeks.
Chiers, Koen +6 more
core +13 more sources
Differential regulation of Type 1 and Type 2 mouse eosinophil activation by apoptotic cells
Frontiers in Immunology, 2022 Eosinophils are multifunctional, evolutionary conserved leukocytes that are involved in a plethora of responses ranging from regulation of tissue homeostasis, host defense and cancer. Although eosinophils have been studied mostly in the context of Type 2
Avishay Dolitzky +8 more
doaj +1 more source
Eosinophils: A Friend or Foe in human health and diseases
Kidney Diseases, 2022 Since their discovery, around 150 years, eosinophils research has been a field of changing perspective, and new directions are emerging since then. Initially, eosinophils were perceived as terminally-differentiated cytotoxic effector cells.
Madiha Zahra Syeda +4 more
doaj +1 more source