Results 161 to 170 of about 232,004 (343)

Lung-resident eosinophils represent a distinct regulatory eosinophil subset.

Journal of Clinical Investigation, 2016
Claire Mesnil, Stéfanie Raulier, G. Paulissen, Xue-lu Xiao, M. Birrell, Dimitri Pirottin, Thibaut J. Janss, P. Starkl, E. Ramery, M. Henket, F. Schleich, M. Radermecker, K. Thielemans, L. Gillet, M. Thiry, M. Belvisi, R. Louis, C. Desmet, T. Marichal, F. Bureau   +19 more
semanticscholar   +1 more source

Molecular stratification of antiphospholipid syndrome through integrative analysis of the whole‐blood RNA transcriptome

Arthritis &Rheumatology, Accepted Article.
Objective Antiphospholipid syndrome (APS) is a thrombo‐inflammatory disorder characterized by clinical and mechanistic heterogeneity that complicates early diagnosis and hinders targeted treatment. We aimed to identify distinct molecular endotypes among antiphospholipid antibody (aPL)‐positive patients using whole‐blood transcriptomics.
Amala Ambati, Feiyang Ma, Katarina Kmetova, Sherwin Navaz, Claire K. Hoy, Cyrus Sarosh, Ajay Tambralli, Erika Navarro‐Mendoza, Johann E. Gudjonsson, J. Michelle Kahlenberg, Jacqueline A. Madison, Alí Duarte‐García, Jason S. Knight, Yu Zuo   +13 more
wiley   +1 more source

OGFRL1 deficiency causes CRMO via pathological osteoclastogenesis, with therapeutic response to TNF inhibitor

Arthritis &Rheumatology, Accepted Article.
Objectives To verify the pathogenesis of the OGFRL1 loss‐of‐function variant (c.30del, p. F10Ffs*110) identified in a CRMO patient and investigate the underlying mechanism. Methods Whole exome sequencing and Sanger sequencing were performed to identify and confirm the variant.
Wen Xiong, Yusha Wang, Tingyan He, Jinjian Fu, Ying Luo, Jinbo Wang, Jun Wang, Xiaomin Yu, Qing Zhou, Jun Yang   +9 more
wiley   +1 more source

The molecular circadian clock of eosinophils: a potential therapeutic target for asthma [PDF]

Julia Teppan, Thomas Bärnthaler, Aitak Farzi, Hannah Durrington, G Tavernier, Hazel Platt, Peter Wolf, Ákos Heinemann, Eva M. Sturm   +8 more
openalex   +1 more source

Identification of C3 beta chain as the human serum eosinophil cytotoxicity inhibitor. [PDF]

, 1991
Marjorie Sue Minkoff, W. Wei‐Lynn Wong, David S. Silberstein   +2 more
openalex   +1 more source

Age‐related differences in hydroxychloroquine‐associated adverse events: A pharmacovigilance study based on the FDA Adverse Event Reporting System

British Journal of Clinical Pharmacology, EarlyView.
Aims This real‐world pharmacovigilance study utilizes FDA Adverse Event Reporting System (FAERS) data (2004–2024) to characterize age‐related disparities in hydroxychloroquine (HCQ)‐associated adverse events (AEs), addressing gaps in age‐stratified risk assessment. Methods Disproportionality analysis (reporting odds ratios, RORs) and parametric Weibull
Guanghan Sun, Jingrong Yang, Lei Wan, Xia Xu, Jing Wang   +4 more
wiley   +1 more source

Elevated Plasma Chemokines for Eosinophils in Neuromyelitis Optica Spectrum Disorders during Remission

, 2018
Yanping Tong, Tao Yang, Jingwen Wang, Tianyou Zhao, Lei Wang, Yuezhi Kang, Cuicui Cheng, Yongping Fan   +7 more
openalex   +1 more source

Comparative evaluation of eosinophils in normal mucosa, dysplastic mucosa and oral squamous cell carcinoma with hematoxylin-eosin, Congo red, and EMR1 immunohistochemical staining techniques.

, 2015
Neda Kargahi, Sayyed Mohammad Razavi, Parviz Deyhimi, Solmaz Homayouni   +3 more
openalex   +2 more sources

Nanomaterial‐based immune therapeutic strategies in neurodegenerative diseases

BMEMat, EarlyView.
This review highlights the immunomodulatory potential of nanomaterials (NMs) in treating neurodegenerative diseases (NDs). It focuses on their roles in regulating innate and adaptive immune responses to maintain immune homeostasis. By providing insights into these mechanisms, the review lays the groundwork for innovative NMs therapeutic strategies to ...
Xinru Zhou, Jia Liu, Shulin Lai, Suhan Yin, Bingmin Luo, Longquan Shao, Yiyuan Kang   +6 more
wiley   +1 more source

Persistent and unstable eosinophil levels in the sputum and blood: impact on the clinical prognosis of patients with chronic obstructive pulmonary disease. [PDF]

J Thorac Dis
Peng J, Wu X, Wen X, Deng Z, Wu F, Tang G, Wan Q, Dai C, Zhou K, Lu L, Chen S, Yang C, Huang Y, Yu S, Ran P, Zhou Y.   +15 more
europepmc   +1 more source