Results 171 to 180 of about 171,953 (311)

High‐Dimensional Spectral Flow Cytometry Panel for Immunophenotypic Characterization of Fixed Whole Blood Samples

Cytometry Part A, EarlyView.
ABSTRACT Peripheral blood mononuclear cells (PBMCs) are commonly used for immune profiling in clinical research, but their isolation and cryopreservation present logistical challenges, particularly in settings with limited access to research facilities. To address this, we implemented a whole blood fixation protocol to preserve surface protein epitopes
Vaishnavi Parthasarathy, Alexander T. Heubeck, Tyanna Stuckey, Veronica Hernandez, Blessing Musgrove, Maia M. Bennett‐Boehm, Troy Torgerson, Peter Skene, Julian Reading   +8 more
wiley   +1 more source

Immunoregulatory mechanisms in parasitic eosinophilic lung disease: the role of IgE immune complexes and NLRC4 inflammasome. [PDF]

Front Immunol
Cao Y, Rao D, Peng Z, Chen Z, Xia Q, Xie C, Fu Y, Huang D, Zhang Z, Yao C.   +9 more
europepmc   +1 more source

Coexistence of immunophenotypically normal and aberrant mast cells in patients with clonal mast cell diseases associates with more indolent subtypes and less severe disease characteristics

Cytometry Part B: Clinical Cytometry, EarlyView.
Abstract Aberrant antigen expression on mast cells (MCs) is one of the most accurate diagnostic markers for clonal MC diseases (CMCD). Although the coexistence of normal and pathologic MCs is frequently seen, the disease characteristics associated with it have been minimally investigated.
Abdulrazzaq Alheraky, Kees Meijer, Marije Nijk, Saskia K. Klein, Hanneke N. G. Oude Elberink, Ido P. Kema, André B. Mulder   +6 more
wiley   +1 more source

Eosinophil Extracellular Traps in Health and Disease: From Host Defense to Chronic Inflammation. [PDF]

Biomedicines
Stojanovic B, Djokic B, Stojanovic BS, Stojanovic MD, Jovanovic J, Matic A.   +5 more
europepmc   +1 more source

Challenges and Pitfalls to Diagnosing NUTM1‐Rearranged Neoplasia of the Pancreas by Cytology and Ancillary Studies

Diagnostic Cytopathology, EarlyView.
ABSTRACT Fine‐needle aspiration cytology specimens are frequently utilized for ancillary studies to identify diagnostic and prognostic information. This case highlights diagnostic pitfalls and challenges in diagnosing NUTM1‐rearranged neoplasia on pancreatic cytology.
Terrance J. Lynn
wiley   +1 more source

Characterization of PAPP-A Patterns in Chronic Rhinosinusitis. [PDF]

J Inflamm Res
Ennahal A, Wendler O, Pesold VV, Mueller SK.   +3 more
europepmc   +1 more source

Primary Pulmonary Mesenchymal Neoplasm With EWSR1::CREM Fusion: Cytologic Findings and Molecular Diagnosis

Diagnostic Cytopathology, EarlyView.
ABSTRACT Background Primary pulmonary mesenchymal neoplasms with EWSR1::CREM fusion are rare. These lesions are challenging to diagnose by morphology and immunohistochemistry alone. Case A 66‐year‐old woman (ex‐smoker) was found to have a 1.3‐cm right lower lobe lung nodule that had grown very slowly over a 9‐year period.
Priya Upadhyay, Sanjay Mukhopadhyay, Swikrity U. Baskota   +2 more
wiley   +1 more source

Mepolizumab in Pediatric Severe Eosinophilic Asthma: A Review of Efficacy, Safety, and Clinical Applications. [PDF]

J Inflamm Res
Bajeli M, Corsello A, Foti Randazzese S, Marseglia A, D'Agostino P, Rossi CM, Marseglia GL, Licari A.   +7 more
europepmc   +1 more source

Epithelioid Enigma: Proximal‐Type Epithelioid Sarcoma in Cyst Fluid Cytology

Diagnostic Cytopathology, EarlyView.
ABSTRACT Epithelioid sarcoma (ES) is a rare, aggressive soft tissue malignancy with substantial morphologic overlap with other epithelioid neoplasms, creating diagnostic difficulty in cytology specimens. We report proximal‐type ES identified in cyst fluid from a lesion clinically interpreted as an epidermal inclusion cyst or abscess.
Nathan McGrath, Azfar Neyaz, Samer Khader   +2 more
wiley   +1 more source

Distinct miRNA expression patterns in circulating eosinophil subtypes and their subtype-derived exosomes in allergic asthma. [PDF]

Inflamm Res
Vasyle E, Januskevicius A, Rimkunas A, Palacionyte J, Miliauskas S, Malakauskas K.   +5 more
europepmc   +1 more source