Results 111 to 120 of about 23,392 (228)

Circulating granulocyte colony‐stimulating factor as a sex‐unbiased global marker of lung and colorectal cancer cachexia pre‐clinical models

Experimental Physiology, EarlyView.
Abstract Cancer cachexia, affecting up to 80% of patients with advanced cancer, is characterized by metabolic and inflammatory dysregulation driven by tumour‐ and host‐derived factors. Although cytokines are central to cachexia pathogenesis, their circulating profiles and transcriptional relevance across models and sexes remain incompletely defined. We
Francielly Morena, Eleanor R. Schrems, Ana Regina Cabrera, Ruqaiza Muhyudin, Sepideh Shakeri, Stavroula Tsitkanou, Mark Viggars, Tyrone A. Washington, Nicholas P. Greene   +8 more
wiley   +1 more source

Acute and lifelong exercise modulate the tumorigenic potential of human lung cancer cells and their susceptibility to cisplatin

Experimental Physiology, EarlyView.
Abstract The association between higher levels of physical activity and lower cancer risk and mortality is well established. However, a causal link is yet to be proven. Recent studies showed a decrease in the proliferation rates of cultured human cancer cells when the human serum used to stimulate them was conditioned by acute exercise. Here, we tested
Carlos M. Soares, João P. Moura, Leonardo M. R. Ferreira, Ana Pedrosa, Pedro Filipe, Luís Rama, Ana M. Teixeira, Ana M. Urbano   +7 more
wiley   +1 more source

Mucosal output of eotaxin in allergic rhinitis and its attenuation by topical glucocorticosteroid treatment

, 2001
BACKGROUND: Eotaxin is a chemokine that attracts and activates eosinophils. The present study examines the occurrence of eotaxin in nasal mucosal surface liquids in patients with seasonal allergic rhinitis without allergen exposure and during repeat ...
Erjefält, Jonas,, Persson, C G, L. Greiff, M. Linden, C. G. A. Persson, Greiff, Lennart, J. S. Erjefält, E. Mattsson, Petersen, H, H. Petersen, Andersson, M, Erjefält, Jonas, C. Svensson, Greiff, Lennart,, Lund University., Linden, M, Svensson, C, Mattsson, E, M. Andersson   +18 more
core   +2 more sources

Senolytics and exercise: Dual modalities for rejuvenating muscle

The Journal of Physiology, EarlyView.
Abstract figure legend The role of senolytics on the heart and skeletal muscle. Senescent cell burden increases with ageing, disuse and disease. The senolytics dasatinib+quercetin (D+Q), navitoclax and fisetin, as well as exercise, eliminate senescent cells, reducing senescent cell burden and their senescence‐associated secretory phenotype (SASP ...
Zeynep Elif Yesilyurt‐Dirican, Ce Qi, Uchenna Okpechi, Maya Strand Ford, Georgina M. Ellison‐Hughes   +4 more
wiley   +1 more source

Phthalate Metabolite, Mono(2‐Ethyl‐5‐Hydroxyhexyl) Phthalate (MEHHP), Promotes Uterine‐Fibroid–Associated Phenotypes in Myometrial Stem Cell‐Derived 3D Organoids

Environmental Toxicology, Volume 41, Issue 10, Page 975-997, October 2026.
ABSTRACT This study investigates how phthalate exposure contributes to uterine fibroid (UF) development by studying the effects of the Mono‐(2‐ethyl‐5‐hydroxyhexyl) phthalate (MEHHP), a metabolite of Di(2‐ethylhexyl) phthalate, on myometrial stem cells (MMSCs).
Somayeh Vafaei, Mervat M. Omran, Qiwei Yang, Sandra Madueke‐Laveaux, Ami R. Zota, Ayman Al‐Hendy, Mohamed Ali   +6 more
wiley   +1 more source

eotaxin

Citation: 'eotaxin' in the IUPAC Compendium of Chemical Terminology, 5th ed.; International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.13119 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
openaire   +1 more source

HMGB1 has no impact on eotaxin-2-mediated chemotaxis.

, 2015
Chemotaxis of peripheral blood eosinophils from normal donors evaluated in response to (A) increasing concentrations of human eotaxin-2 in the presence or absence of 10 ng/mL HMGB1 or (B) 100 nM human eotaxin-2 (hE2) in the presence of increasing ...
Kimberly D. Dyer (7353), Helene F. Rosenberg (7354)   +1 more
core   +1 more source

Marked Long‐Term Improvement in Lung Function in Melanoma Differentiation–Associated Protein 5 Antibody–Positive Dermatomyositis Patients: Experience of a Single‐Center Longitudinal Cohort in North America

Arthritis Care &Research, Volume 78, Issue 9, Page 1112-1122, September 2026.
Objective The objective of this study was to describe the longitudinal disease course and pulmonary outcomes of North American patients with melanoma differentiation–associated protein 5 (MDA5) antibody–associated dermatomyositis (DM). Methods Thirty patients with MDA5 antibody–associated DM were identified in a single‐center longitudinal cohort of 352
Jenice X. Cheah, Sangmee S. Bae, Tiffany De Leon, Yuna Lee, Rong Guo, David Elashoff, Jennifer Wang, Ani Shahbazian, Christina Charles‐Schoeman   +8 more
wiley   +1 more source

The Cog‐Aging: a 15‐year cohort study of cognition in Brazilian older adults

Alzheimer's &Dementia, Volume 22, Issue 9, September 2026.
Abstract BACKGROUND Prevalence of dementia is higher in low‐ and middle‐income countries (LMICs). However, longitudinal studies characterizing cognitive decline and its clinical and epidemiological predictors remain scarce in Brazil. METHODS Participants were enrolled from 2011 to 2025 and followed through May 2026.
Gabriela Tomé Oliveira Engelmann, Joice Coutinho de Alvarenga, Giovanna Correia Pereira Moro, Ivonne Carolina Bolaños Burgos, Mariana Figueiredo Miranda, Millena Figueiredo Miranda, Aline Siqueira de Souza, Marcelle Ferreira Saldanha, Erika Oliveira Hansen, Natalia Silva Dias, Fabiana Carla Matos da Cunha Cintra, Bruna Fulgêncio Dias, Anna Luiza da Silva Souza, Andréa Teixeira Carvalho, Pamela V. Martino‐Adami, Marco Túlio Gualberto Cintra, Ludimila Labanca, Igor Nunes Lanna, Rafaela Teixeira de Ávila, Jonas Jardim de Paula, Luciana Costa‐Silva, Daniela Valadão Freitas Rosa, Débora Marques de Miranda, Marco Aurélio Romano‐Silva, Luiz Armando Cunha de Marco, Alfredo Ramírez, Bernardo de Mattos Viana, Maria Aparecida Camargos Bicalho   +27 more
wiley   +1 more source

Measurement of eotaxin (CCL11) in induced sputum supernatants: validation and detection in asthma

, 2004
Background Induced sputum is widely used in asthma research; however, for many mediators, the detection methods have not been validated.Objective We sought to optimize the method of detection of eotaxin, an important chemokine acting through the CCR3 ...
Hadjicharalambous, Chrystalleni, Dent, Gordon, Handy, Rachel L.C., Djukanovic, Ratko, Davies, Donna E., Anderson, Ian K., May, Richard D.   +6 more
core   +1 more source