Results 151 to 160 of about 19,297 (197)
Some of the next articles are maybe not open access.
Current Opinion in Pharmacology, 2001
Eotaxin is a small protein that is produced in the lungs of asthmatic patients and is a potent chemoattractant for eosinophils. Eotaxin, a CC chemokine, stimulates the migration of eosinophils from the small blood vessels in the lungs by acting on the CC chemokine receptor CCR3, which is located on the leukocyte cell surface.
James Pease, Timothy J Williams
exaly +3 more sources
Eotaxin is a small protein that is produced in the lungs of asthmatic patients and is a potent chemoattractant for eosinophils. Eotaxin, a CC chemokine, stimulates the migration of eosinophils from the small blood vessels in the lungs by acting on the CC chemokine receptor CCR3, which is located on the leukocyte cell surface.
James Pease, Timothy J Williams
exaly +3 more sources
Concerted expression of eotaxin-1, eotaxin-2, and eotaxin-3 in human bronchial epithelial cells
Cellular Immunology, 2003Eotaxin-1/CCL11, eotaxin-2/CCL24, and eotaxin-3/CCL26 bind specifically and exclusively to CC chemokine receptor (CCR) 3, which is a potential therapeutic target in treating the peribronchial eosinophilia associated with allergic airway diseases. Bronchial epithelial cells represent an important source of chemokines, and thus we investigated in vitro ...
Akiko, Komiya +12 more
openaire +3 more sources
Tear and mucus eotaxin-1 and eotaxin-2 in allergic keratoconjunctivitis
Ophthalmology, 2003Eotaxin-1 and eotaxin-2 are potent eosinophil chemotactic and activating peptides that may be implicated in the pathogenesis of the chronic allergic eye diseases vernal keratoconjunctivitis (VKC) and atopic keratoconjunctivitis (AKC). The purpose of this study was to measure these chemokines in tear and mucus samples of active-disease patients and in ...
Andrea, Leonardi +3 more
openaire +4 more sources
RANTES, eotaxin and eotaxin‐2 expression and production in patients with aspirin triad
Allergy, 2003Background: Polyposis, asthma, aspirin‐intolerance and aspirin‐triad are mostly accompanied with eosinophilia of mucosal airways. Chemotactic cytokines, the CC‐chemokines regulated on activation, normal T‐cell expressed (RANTES), eotaxin, and eotaxin‐2 activate and attract eosinophilic leukocytes to the site of inflammation.
R, Pods +4 more
openaire +2 more sources
1999
Asthma is a common disease affecting approx 10% of the population in developed countries, and the prevalence and mortality are rising. The disease has characteristic symptoms, namely intermittent airway obstruction, airway hyperresponsiveness, and increased numbers of activated inflammatory cells and airway structural changes as a result of chronic ...
Dolores M. Conroy, Timothy J. Williams
openaire +1 more source
Asthma is a common disease affecting approx 10% of the population in developed countries, and the prevalence and mortality are rising. The disease has characteristic symptoms, namely intermittent airway obstruction, airway hyperresponsiveness, and increased numbers of activated inflammatory cells and airway structural changes as a result of chronic ...
Dolores M. Conroy, Timothy J. Williams
openaire +1 more source
Ontogeny of the eotaxins in human lung
American Journal of Physiology-Lung Cellular and Molecular Physiology, 2008The ontogeny of the C-C chemokines eotaxin-1, eotaxin-2, and eotaxin-3 has not been fully elucidated in human lung. We explored a possible role for eotaxin in developing lung by determining the ontogeny of eotaxin-1 (CCL11), eotaxin-2 (CCL24), eotaxin-3 (CCL26), and the eotaxin receptor, CCR3.
Kathleen J, Haley +8 more
openaire +2 more sources
Eosinophilic nasal polyps are a rich source of eotaxin, eotaxin-2 and eotaxin-3.
Rhinology, 2006The CC-chemokine eotaxin plays a key role in the pathologic mechanism of tissue eosinophilia in nasal polyposis. In this study, we investigated a possible role of eotaxin-2 and eotaxin-3, the recently discovered members of the eotaxin family.Nasal polyps from 24 patients (non allergic/allergic/aspirin-intolerant patients) and turbinate tissue from 8 ...
H, Olze +4 more
openaire +1 more source
Cytokines, Chemokines, RANTES, and Eotaxin
Allergy and Asthma Proceedings, 1999Over the past several years, a number of cytokines with chemoattractive properties (chemokines) have been identified. These low molecular weight molecules have been shown to be important leukocyte chemical attractants to sites of inflammation and infection.
F M, Graziano, E B, Cook, J L, Stahl
openaire +2 more sources
[Effects of corticosteroid on Eotaxin and Eotaxin-2 in nasal polyps].
Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology head and neck surgery, 2011To study the expression of Eotaxin and Eotaxin-2 in nasal polyp and observe the effects of steroids on Eotaxin and Eotaxin-2 in nasal polyps.The SP immunohistochemical method was applied to explore the expression of Eotaxin and Eotaxin-2 in nasal polyps before and after systemic corticosteroids therapy; the optical density of positive cells were ...
Xianhong, Wang, Shusheng, Gong
openaire +1 more source