Results 181 to 190 of about 23,392 (228)
Journal of Allergy and Clinical Immunology, 2005 BACKGROUND: Eotaxin-1, eotaxin-2, and eotaxin-3 are chemokines involved in the activation and recruitment of eosinophils through activation of their main receptor, CC chemokine receptor 3.
Pieter Hiemstra, Mauad T, Klaus F Rabe
exaly +2 more sources
Smoking Affects Eotaxin Levels in Asthma Patients
Journal of Asthma, 2009 BACKGROUND: Chronic airway inflammation is most important pathological finding in asthma. Cigarette smoking may modify type of inflammation as well as may influence disease severity and response to the treatment. OBJECTIVE: Thus the aim of this study was
Jan Lotvall +2 more
exaly +2 more sources
Some of the next articles are maybe not open access.
Related searches:
Related searches:
Current Opinion in Pharmacology, 2001
Eotaxin is a small protein that is produced in the lungs of asthmatic patients and is a potent chemoattractant for eosinophils. Eotaxin, a CC chemokine, stimulates the migration of eosinophils from the small blood vessels in the lungs by acting on the CC chemokine receptor CCR3, which is located on the leukocyte cell surface.
James Pease
exaly +3 more sources
Eotaxin is a small protein that is produced in the lungs of asthmatic patients and is a potent chemoattractant for eosinophils. Eotaxin, a CC chemokine, stimulates the migration of eosinophils from the small blood vessels in the lungs by acting on the CC chemokine receptor CCR3, which is located on the leukocyte cell surface.
James Pease
exaly +3 more sources
Intracellular localization and release of eotaxin from normal eosinophils [PDF]
FEBS Letters, 1998 Eotaxin is a potent and selective CC chemokine for eosinophils and basophils. We established several monoclonal antibodies (Mabs) allowing the neutralization and measurement of human eotaxin.
Kazuhiko Yamamoto +2 more
exaly +2 more sources
Detection of mRNA for Eotaxin-2 and Eotaxin-3 in Human Dermal Fibroblasts and Their Distinct Activation Profile on Human Eosinophils [PDF]
Journal of Investigative Dermatology, 2001 As many new biologically active chemokines have been cloned exploring the genomic DNA sequence database in the vicinity of already known chemokine sequences without demonstrating their natural origin, it is important to transfer findings from in vitro ...
Alexander Kapp, Jorn Elsner, D Kimmig
exaly +2 more sources
1999
Asthma is a common disease affecting approx 10% of the population in developed countries, and the prevalence and mortality are rising. The disease has characteristic symptoms, namely intermittent airway obstruction, airway hyperresponsiveness, and increased numbers of activated inflammatory cells and airway structural changes as a result of chronic ...
Dolores M. Conroy, Timothy J. Williams
openaire +1 more source
Asthma is a common disease affecting approx 10% of the population in developed countries, and the prevalence and mortality are rising. The disease has characteristic symptoms, namely intermittent airway obstruction, airway hyperresponsiveness, and increased numbers of activated inflammatory cells and airway structural changes as a result of chronic ...
Dolores M. Conroy, Timothy J. Williams
openaire +1 more source
RANTES, eotaxin and eotaxin‐2 expression and production in patients with aspirin triad
Allergy, 2003Background: Polyposis, asthma, aspirin‐intolerance and aspirin‐triad are mostly accompanied with eosinophilia of mucosal airways. Chemotactic cytokines, the CC‐chemokines regulated on activation, normal T‐cell expressed (RANTES), eotaxin, and eotaxin‐2 activate and attract eosinophilic leukocytes to the site of inflammation.
R, Pods +4 more
openaire +2 more sources
Ontogeny of the eotaxins in human lung
American Journal of Physiology-Lung Cellular and Molecular Physiology, 2008The ontogeny of the C-C chemokines eotaxin-1, eotaxin-2, and eotaxin-3 has not been fully elucidated in human lung. We explored a possible role for eotaxin in developing lung by determining the ontogeny of eotaxin-1 (CCL11), eotaxin-2 (CCL24), eotaxin-3 (CCL26), and the eotaxin receptor, CCR3.
Kathleen J, Haley +8 more
openaire +2 more sources
Eosinophilic nasal polyps are a rich source of eotaxin, eotaxin-2 and eotaxin-3.
Rhinology, 2006The CC-chemokine eotaxin plays a key role in the pathologic mechanism of tissue eosinophilia in nasal polyposis. In this study, we investigated a possible role of eotaxin-2 and eotaxin-3, the recently discovered members of the eotaxin family.Nasal polyps from 24 patients (non allergic/allergic/aspirin-intolerant patients) and turbinate tissue from 8 ...
H, Olze +4 more
openaire +1 more source
Cytokines, Chemokines, RANTES, and Eotaxin
Allergy and Asthma Proceedings, 1999Over the past several years, a number of cytokines with chemoattractive properties (chemokines) have been identified. These low molecular weight molecules have been shown to be important leukocyte chemical attractants to sites of inflammation and infection.
F M, Graziano, E B, Cook, J L, Stahl
openaire +2 more sources