Results 51 to 60 of about 11,193 (295)

How Transformational Supply Chain Leadership Affects Financial and Environmental Performance: The Mediating Role of Firm Resilience to Supply Disruption

open access: yesBusiness Strategy and the Environment, EarlyView.
ABSTRACT Existing literature indicates that transformational leadership in supply chains is critical to sustainability; however, little is known about how this leadership influences sustainability. The empirical literature has provided minimal focused analysis of transformational supply chain leadership and its effects on sustainability performance ...
Ishmael Nanaba Acquah   +2 more
wiley   +1 more source

Prediction of arrhythmic events by Wedensky modulation in patients with coronary artery disease

open access: yesSwiss Medical Weekly, 2014
PRINCIPLES: Prediction of arrhythmic events (AEs) has gained importance with the availability of implantable cardioverter-defibrillators (ICDs), but is still imprecise.
Andreas W Schoenenberger   +3 more
doaj   +1 more source

Circling the Archetype: Tensions Limiting the Transformation to a Circular Economy

open access: yesBusiness Strategy and the Environment, EarlyView.
ABSTRACT This research examines key tensions and the archetypal paradox that prevent the transformation to a circular economy (CE) across individual, organizational, and systems levels, problematizing CE assumptions. Tension manifestations are analyzed using a qualitative case study across eight diverse industries and geographies.
Helleke Heikkinen   +5 more
wiley   +1 more source

Potent, Selective, Water Soluble, Brain-Permeable EP2 Receptor Antagonist for Use in Central Nervous System Disease Models

open access: yes, 2020
Activation of prostanoid EP2 receptor exacerbates neuroinflammatory and neurodegenerative pathology in central nervous system diseases such as epilepsy, Alzheimer’s disease, and cerebral aneurysms.
Ray Dingledine (1319991)   +8 more
core   +2 more sources

Bone marrow mesenchymal stem cell‐derived exosomes improve renal fibrosis by reducing the polarisation of M1 and M2 macrophages through the activation of EP2 receptors

open access: yesIET Nanobiotechnology, 2022
Renal fibrosis is the pathological outcome of most end‐stage renal diseases, yet there are still limited therapeutic options for it. In recent years, bone marrow mesenchymal stem cell‐derived exosomes (BM‐MSCs) have received much attention.
Yuqing Lu   +5 more
doaj   +1 more source

Discovery and Characterization of Carbamothioylacrylamides As EP2 Selective Antagonists

open access: yes, 2016
Prostanoid receptor EP2 is emerging as a novel target for development of anti-inflammatory drugs for the treatment of chronic neurodegenerative and peripheral diseases; however, the availability of EP2 antagonist probes for exploration of peripheral ...
Jianxiong Jiang (464031)   +3 more
core   +1 more source

Don't Just Train, Inspire: The Critical Role of Motivation in Corporate Green Behavior

open access: yesBusiness Strategy and the Environment, EarlyView.
ABSTRACT This study examines how green training influences corporate green behavior, with a particular focus on the mediating role of organizational green motivation. Drawing on the resource‐based view and the ability‐motivation‐opportunity framework, we propose a model in which green training builds environmental capability and fosters motivation ...
Marta Mas‐Machuca   +2 more
wiley   +1 more source

Prostaglandin E2 receptor subtype 2 (EP2) regulates microglial activation and associated neurotoxicity induced by aggregated α-synuclein

open access: yesJournal of Neuroinflammation, 2007
Background The pathogenesis of idiopathic Parkinson's disease (PD) remains elusive, although evidence has suggested that neuroinflammation characterized by activation of resident microglia in the brain may contribute significantly to neurodegeneration in
Schantz Aimee M   +8 more
doaj   +1 more source

Seminal plasma and prostaglandin E2 up-regulate fibroblast growth factor 2 expression in endometrial adenocarcinoma cells via E-series prostanoid-2 receptor-mediated transactivation of the epidermal growth factor receptor and extracellular signal-regulated kinase pathway [PDF]

open access: yes, 2007
Prostaglandin E(2) (PGE(2)) has been shown to modulate angiogenesis and tumour progression via the E-series prostanoid-2 (EP2) receptor. Endometrial adenocarcinomas may be exposed to endogenous PGE(2) and exogenous PGE(2), present at high concentration ...
Williams, A R   +5 more
core   +1 more source

Driving Circularity Upstream: The Mediating Role of Circular Supply Chain Management in Environmental Performance

open access: yesBusiness Strategy and the Environment, EarlyView.
ABSTRACT The transition toward a circular economy has gained growing prominence as a means to reduce supply chain waste and enhance environmental performance, yet its success ultimately depends on effective collaboration among supply chain partners. This study aims to explore the factors that influence the adoption of circular practices in the upstream
Noelia Garcia‐Buendia   +4 more
wiley   +1 more source

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