Results 31 to 40 of about 11,193 (295)

Role of prostaglandin E receptor subtypes EP2 and EP4 in autocrine and paracrine functions of vascular endothelial growth factor in the inner ear

BMC Neuroscience, 2010
Background The physiological effects of prostaglandin E1 (PGE1) and prostaglandin E2 (PGE2) are mediated by the prostaglandin E receptor subtypes EP1, EP2, EP3, and EP4, and the respective agonists have been purified.
Hamaguchi Kiyomi, Yamamoto Norio, Nakagawa Takayuki, Hori Ryusuke, Ito Juichi   +4 more
doaj   +1 more source

Exercise on a vibratory platform increases blood perfusion on the stifle joint and rectal temperature in healthy dogs [PDF]

Arquivo Brasileiro de Medicina Veterinária e Zootecnia, 2020
The effects of two vibration platform (VP) exercise protocols on stifle and rectal temperatures were evaluated. Eleven animals participated in two exercise protocols, different in duration in each exercise.
J.A. Villanova Junior, G. Dipp, B.M. Viveiros, J.L. Balardini, L.J.E. Isaka, C.L. Santos, G.H. Gomes, C.T. Pimpão, P.V. Michelotto Junior   +8 more
doaj   +1 more source

Effect of deletion of the prostaglandin EP2 receptor on the anabolic response to prostaglandin E2 and a selective EP2 receptor agonist [PDF]

Prostaglandins & Other Lipid Mediators, 2008
Studies using prostaglandin E receptor (EP) agonists indicate that prostaglandin (PG) E(2) can have anabolic effects through both EP4 and EP2 receptors. We previously found that the anabolic response to a selective EP4 receptor agonist (EP4A, Ono Pharmaceutical) was substantially greater than to a selective EP2 receptor agonist (EP2A) in cultured ...
Shilpa, Choudhary, Cynthia, Alander, Peili, Zhan, Qi, Gao, Carol, Pilbeam, Lawrence, Raisz   +5 more
openaire   +2 more sources

Cloning and expression of the rabbit prostaglandin EP2 receptor [PDF]

BMC Pharmacology, 2002
Prostaglandin E2 (PGE2) has multiple physiologic roles mediated by G protein coupled receptors designated E-prostanoid, or "EP" receptors. Evidence supports an important role for the EP2 receptor in regulating fertility, vascular tone and renal function.The full-length rabbit EP2 receptor cDNA was cloned. The encoded polypeptide contains 361 amino acid
Guan, Youfei, Stillman, Brett A, Zhang, Yahua, Schneider, André, Saito, Osamu, Davis, Linda S, Redha, Reyadh, Breyer, Richard M, Breyer, Matthew D   +8 more
openaire   +2 more sources

Edition of Prostaglandin E2 Receptors EP2 and EP4 by CRISPR/Cas9 Technology in Equine Adipose Mesenchymal Stem Cells

Animals, 2020
In mesenchymal stem cells (MSCs), it has been reported that prostaglandin E2 (PGE2) stimulation of EP2 and EP4 receptors triggers processes such as migration, self-renewal, survival, and proliferation, and their activation is involved in homing.
Ana Carolina Furlanetto Mançanares, Joel Cabezas, José Manríquez, Vanessa Cristina de Oliveira, Yat Sen Wong Alvaro, Daniela Rojas, Felipe Navarrete Aguirre, Lleretny Rodriguez-Alvarez, Fidel Ovidio Castro   +8 more
doaj   +1 more source

EP2 self-assembles into amyloid fibrils.

, 2015
(A) Different concentrations of EP2 formed amyloid fibrils immediately after gradient dilution, as shown by ThT assay results. (B) EP2 (2 mg/ml) rapidly formed amyloid aggregates, as shown by ThT assay results (every 5 min for 30 min).
Xuanxuan Zhang (837186), Fei Yu (61577), Tianrong Xun (797811), Shuwen Liu (146709), Lin Li (28817), Suiyi Tan (366530), Wanyue Zhang (837185), Shibo Jiang (275873), Jinquan Chen (837183), Ruxia Ren (837184)   +9 more
core   +1 more source

Realizing strong photon blockade at exceptional points in the weak coupling regime

Frontiers in Physics, 2023
We theoretically prove that it is possible to realize strong photon blockade at n-order exceptional points (EPn) in a two-level quantum emitter (QE)–cavity quantum electrodynamics (QED) system even if the emitter–cavity coupling strength is weak.
Zigeng Li, Xiaomiao Li, Guofeng Zhang, Xiaolan Zhong   +3 more
doaj   +1 more source

Emotion Regulation Difficulties in Autism‐PTSD Co‐Occurrence

Autism Research, EarlyView.
ABSTRACT Autistic individuals face an increased risk of experiencing traumatic events and of being significantly affected by them, whether these events are life‐threatening or social in nature. Emotion regulation (ER) difficulties are central to both conditions, yet their role in this neuropsychiatric co‐occurrence remains under‐researched.
Eldar Fayena, Shir Shaked‐Ashkenazi, Michal Shoval, Mordi Benhamou, Nathaniel Laor, Danny Horesh, Ofer Golan   +6 more
wiley   +1 more source

Validation of the ABL + DT model: An ecosystemic framework for integrating arts and digital technologies in primary education

British Educational Research Journal, EarlyView.
Abstract Primary education teachers face increasing challenges in engaging diverse learners and fostering creativity, digital competence and other transversal skills, often lacking clear, practical guidance for integrating these skills into their classrooms.
Nella Escala, Montse Guitert, Teresa Romeu   +2 more
wiley   +1 more source

Nanomedicine‐driven innovations in postoperative cancer immunotherapy: Remodeling tumor microenvironment and precision delivery strategies

BMEMat, EarlyView.
Nanomedicine‐Driven Strategies for Suppressing Postoperative Tumor Recurrence. This schematic illustrates three pivotal nanomedical strategies that synergistically counteract recurrence by targeting residual disease and the immunosuppressive tumor microenvironment within the surgical cavity.
Lisong Pang, Zhuomin Wang, Zhenhua Jin, Ahmed H. Ghonaim, Hengcheng Zhang, Xinyu You, Jinzhuo Ning, Jiaqing Cao, Yang Liu   +8 more
wiley   +1 more source