Results 221 to 230 of about 24,553 (253)

Embryonic development: Tracing the origin of epiblast cells

Current Biology
The epiblast is the source of all the cells of our bodies and of the pluripotent embryonic stem cells. Novel work using fluorescent reporter-based cell tracking supports a stochastic mechanism for epiblast differentiation and reveals SOX2 as the most obvious marker.
Violaine, Paulus, Claire, Chazaud
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Isolation and Maintenance of Mouse Epiblast Stem Cells

2010
Epiblast stem cells (EpiSCs) are isolated from the postimplantation mouse embryo just after implantation but prior to gastrulation. EpiSCs are pluripotent and provide a tractable, in vitro system to study the processes that function during gastrulation to transition pluripotent cells to their differentiated derivatives.
Josh G, Chenoweth, Paul J, Tesar
openaire   +2 more sources

Ultrastructural and immunohistochemical characterization of the bovine epiblast.

Biology of reproduction, 2005
The epiblast represents the final embryonic founder cell population with the potential for giving rise to all cell types of the adult body. The pluripotency of the epiblast is lost during the process of gastrulation. Large animal species have a lack of specific markers for pluripotency.
Vejlsted, Morten, Avery, Birthe, Schmidt, Mette, Greve, Torben, Alexopoulos, Natalie, Maddox-Hyttel, Poul   +5 more
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NOGGIN Transport in a Model Human Epiblast

2021
A thesis presented to the faculty of The Rockefeller University in partial fulfillment of the requirements for the degree of Doctor of ...
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Ultrastructure of Auxin-Induced Tumors of the Coleorhiza-Epiblast of Wheat

American Journal of Botany, 1975
When wheat is germinated in high concentrations of certain auxins, the coleorhiza‐epiblast grows in an excessive and disorganized manner and resembles a callus. Wheat was germinated in 10−3 M indoleacetic acid or in water. There was greater net synthesis of DNA, RNA, and protein in the tumor tissue than in control tissue.
Patricia L, Walne, Alan H, Haber, L L, Triplett   +2 more
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New cell lines from mouse epiblast share defining features with human embryonic stem cells

Nature, 2007
P. Tesar, Josh G. Chenoweth, F. Brook, T. J. Davies, E. P. Evans, David L. Mack, R. Gardner, R. McKay   +7 more
semanticscholar   +1 more source

The Epiblast and Pluripotent Stem Cell Lines

All somatic cells develop from the epiblast, which occupies the upper layer of two-layered embryos and in most mammals is formed after the implantation stage but before gastrulation initiates. Once the epiblast is established, the epiblast cells begin to develop into various somatic cells via large-scale cell reorganization, namely, gastrulation ...
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Derivation of pluripotent epiblast stem cells from mammalian embryos

Nature, 2007
I. Brons, L. Smithers, M. Trotter, P. Rugg-Gunn, Bowen Sun, Susana M. Chuva, de Sousa Lopes, S. Howlett, A. Clarkson, L. Åhrlund-Richter, R. Pedersen, L. Vallier   +11 more
semanticscholar   +1 more source

Control of epiblast cell fate by mechanical cues

Summary In amniotes, embryonic tissues originate from multipotent epiblast cells, arranged in a mosaic of presumptive territories. How these domains fated to specific lineages become segregated during body formation remains poorly understood.
Charlène Guillot, Yannis Djeffal, Mattia Serra, Olivier Pourquié   +3 more
openaire   +2 more sources

A 3D model of a human epiblast reveals BMP4-driven symmetry breaking

Nature Cell Biology, 2019
M. Simunovic, J. Metzger, F. Etoc, Anna Yoney, A. Ruzo, I. Martyn, Gist F. Croft, D. You, A. Brivanlou, E. Siggia   +9 more
semanticscholar   +1 more source