Journal of Biological Chemistry, 1973 The three disulfide bridges in epidermal growth factor have been identified by the isolation of three unique cystinyl peptides obtained by thermolytic digestion. The cysteic acid-containing peptide pairs derived from each of the cystinyl peptides were isolated.
Stanley Cohen +2 more
openaire +4 more sources
Close similarity of epidermal growth factor receptor and v-erb-B oncogene protein sequences [PDF]
Nature, 1984 J. Downward +8 more
semanticscholar +2 more sources
Epidermal growth factor receptor (EGFR) gene alteration and protein overexpression in Malaysian triple-negative breast cancer (TNBC) cohort [PDF]
, 2019 Background: Epidermal growth factor receptor (EGFR) is a member of the ErbB family of tyrosine kinase receptor proteins that plays important roles in tumour cell survival and proliferation.
Abdul Raub, Sayyidi Hamzi +7 more
core +1 more source
Structure-Activity Relationship of Indole-Tethered Pyrimidine Derivatives that Concurrently Inhibit Epidermal Growth Factor Receptor and Other Angiokinases. [PDF]
PLoS ONE, 2015 Antiangiogenic agents have been widely investigated in combination with standard chemotherapy or targeted cancer agents for better management of advanced cancers.
Jiho Song +7 more
doaj +1 more source
Effect on the canine Eck fistula liver of intraportal TGF‐β alone or with hepatic growth factors [PDF]
, 1992 Transforming growth factor‐β canceled the hepatocyte proliferation caused by transforming growth factor‐α when the two substances were mixed and administered through a disconnected central portal vein branch after creation of an Eck fistula. In contrast,
Alessandro Azzarone +28 more
core +1 more source
Epidermal Growth Factor Receptor Cell Proliferation Signaling Pathways
Cancers, 2017 The epidermal growth factor receptor (EGFR) is a receptor tyrosine kinase that is commonly upregulated in cancers such as in non-small-cell lung cancer, metastatic colorectal cancer, glioblastoma, head and neck cancer, pancreatic cancer, and breast ...
Ping Wee, Zhixiang Wang
semanticscholar +1 more source
Potential Role of EGF and EGFR in Tongue Coating Formation
World Journal of Traditional Chinese Medicine, 2016 Tongue coating, as a sensitive index of the physiological and pathological changes of human organs, is an important basis for the Traditional Chinese Medicine (TCM) syndrome differentiation and treatment.
Yi-Shuang Tang +4 more
doaj +1 more source
Intraocular Metastases Secondary to Breast Carcinoma Correlates With Upregulation of Estrogen and Progesterone Receptor Expression in the Primary Tumor [PDF]
, 2016 To compare estrogen (ER), progesterone (PR), and human epidermal growth factor-2 (HER2) receptor expression in the primary tumor of patients affected by choroidal metastases from breast carcinoma (BC) versus those with extraocular ...
Frizziero, Luisa +7 more
core +1 more source
Anti epidermal growth factor receptor therapy in small bowel adenocarcinoma [PDF]
, 2018 Rationale:Small bowel adenocarcinoma (SBA) is an uncommon gastrointestinal cancer, thus limited data about treatment for advanced disease are available.
Anselmi, Elisabetta +4 more
core +1 more source
Genome Medicine, 2017 Targeted therapies such as kinase inhibitors and monoclonal antibodies have dramatically altered cancer care in recent decades. Although these targeted therapies have improved patient outcomes in several cancer types, resistance ultimately develops to ...
Leanne G. Ahronian, Ryan B. Corcoran
doaj +1 more source