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Epidermal growth factor in blood
Regulatory Peptides, 1986The presence of receptors for epidermal growth factor (EGF) in a wide variety of human tissues and also some tumours indicates an as yet undefined role for EGF and it is therefore necessary to know precise concentrations in blood and other fluids. We have investigated the occurrence of EGF in the circulation and found that in platelet rich plasma, EGF ...
A.P. Savage +3 more
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Biochemistry, 1989
Epidermal growth factor (EGF) and transforming growth factor alpha (TGF alpha) compete with each other for binding to the EGF receptor. These two growth factors have similar actions, but there are distinguishable differences in their biological activities. It has never been clear how this one receptor can mediate different responses.
Marcy Winget +3 more
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Epidermal growth factor (EGF) and transforming growth factor alpha (TGF alpha) compete with each other for binding to the EGF receptor. These two growth factors have similar actions, but there are distinguishable differences in their biological activities. It has never been clear how this one receptor can mediate different responses.
Marcy Winget +3 more
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Repurposing of the epidermal growth factor
Journal of Commercial Biotechnology, 1969This article deals with repurposing of the epidermal growth factor (EGF) to the treatment of diabetic foot ulcers (DFU) grades III and IV, according to the Wagner scale. The design of a repurposing commercial strategy is described in this document as a contribution to a body of knowledge with high uncertainty and lack of methodology for decision ...
Ernesto López Mola +2 more
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The epidermal growth factor receptor family [PDF]
Endocrine-Related Cancer, 2005 The epidermal growth factor receptor family consists of four receptor genes and at least 11 ligands, several of which are produced in different protein forms. They create an interacting system that has the ability to receive and process information that results in multiple outputs.
L.A. Bazley, William J. Gullick
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2013
The epidermal growth factor family includes a number of cytokines inducing the proliferation of epithelial cells. The founding member (EGF) is a small protein containing 53 aminoacids and 3 disulfide bonds inducing the proliferation of cells sharing its receptor (EGFR), a member of the Erb family widely used as target of anti-tumoral biomedicines ...
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The epidermal growth factor family includes a number of cytokines inducing the proliferation of epithelial cells. The founding member (EGF) is a small protein containing 53 aminoacids and 3 disulfide bonds inducing the proliferation of cells sharing its receptor (EGFR), a member of the Erb family widely used as target of anti-tumoral biomedicines ...
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Thyroid, 2001
Thyroid malignancy has been induced by long-term endogenous thyrotropin (TSH) stimulation in experimental animals, leading to local and distant metastasis. It has been postulated that constant and prolonged endogenous TSH stimulation in dyshormonogenetic thyroid tissues could result in thyroid neoplasia.
Geraldo Medeiros-Neto +3 more
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Thyroid malignancy has been induced by long-term endogenous thyrotropin (TSH) stimulation in experimental animals, leading to local and distant metastasis. It has been postulated that constant and prolonged endogenous TSH stimulation in dyshormonogenetic thyroid tissues could result in thyroid neoplasia.
Geraldo Medeiros-Neto +3 more
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The Epidermal Growth Factor Family
1990During the purification of nerve growth factor from mouse submaxillary glands by carboxymethyl cellulose chromatography, distinct biological activities were noticed when a fraction that did not contain nerve growth promoting activity was injected into newborn mice (Cohen 1960; Levi-Montalcini and Cohen 1960).
M. I. Wahl, Graham Carpenter
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Oncology Reports, 1994
We examined the relationship between epidermal growth factor (EGF) and epidermal growth factor receptor (EGFR) with clinicopathologic variables and silver-stained nuclear organizer region (Ag-NOR) counts in 93 patients with breast cancer. EGFR expression was significantly associated with axillary lymph node metastases, whereas EGF expression was not ...
M Noguchi +5 more
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We examined the relationship between epidermal growth factor (EGF) and epidermal growth factor receptor (EGFR) with clinicopathologic variables and silver-stained nuclear organizer region (Ag-NOR) counts in 93 patients with breast cancer. EGFR expression was significantly associated with axillary lymph node metastases, whereas EGF expression was not ...
M Noguchi +5 more
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Epidermal Growth Factor and Epidermal Growth Factor Signaling Attenuate Laser-Induced Melanogenesis
Dermatologic Surgery, 2013Epidermal growth factor (EGF) is a peptide that promotes cell growth by binding to its receptor (EGFR) on the cell surface. EGF has been used in cosmetics to whiten the skin and for the prevention of postinflammatory hyperpigmentation (PIH), presumably by accelerating wound healing, but the effects of EGF on melanogenesis are not known, and the ...
Kyung-Hyun Min +5 more
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Radioreceptor assay for epidermal growth factor
Analytical Biochemistry, 1979An established cell line of human lung fibroblasts with a high number of surface receptorsfor mouse epidermal growth factor (mEGF) was used to develop a simple and highly sensitive radioreceptor assay for EGF. 125I-Labeled mEGF competed mole for mole with unlabeled mEGF for specific receptors. Optimal range for discriminating EGF concentrations in body
Lynn Mccormick +3 more
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