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Methacrylated Gelatin and Graphene Oxide Hybrid Hydrogels Composed‐Bioinks for 3D Tissue Engineering
Bioinks made from hydrogels, such as methacrylated gelatin (GelMA), serve as the base material for bioprinted tissues, offering versatility and biocompatibility for a range of applications. Additional components however are still needed to improve functionality and mechanical stability of hydrogels. One of these components is graphene oxide (GO), added
Wanessa S. Mota +10 more
wiley +1 more source
Silk fibroin is an attractive natural biomaterial that can be engineered into diverse cardiovascular constructs, including vascular grafts, cardiac patches, heart valves, and stent coatings. Its tunable biological and mechanical properties have driven substantial preclinical progress; however, widespread clinical translation in cardiovascular ...
Mahsa Haghighattalab +8 more
wiley +1 more source
AbstractThe clinical implications of understanding epidermal stem cell biology abound. Thousands of burns victims across the world have benefited from early research into the proliferation of epidermal keratinocytes in vitro. Advances now indicate there are a number of stem cell repositories within the epidermis, two of which, the interfollicular ...
Sally Lowell +2 more
exaly +3 more sources
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Advances in Dermatology, 2005
ABSTRACTThe identification of adult epidermal stem cells that are capable of self‐renewal and can reconstitute not only the epidermis but also the cutaneous appendages opens new perspectives for the treatment of a variety of human skin disorders including severe burns, cutaneous cancers, alopecia and acne. However, the implementation and improvement of
R, Barthel, D, Aberdam
+7 more sources
ABSTRACTThe identification of adult epidermal stem cells that are capable of self‐renewal and can reconstitute not only the epidermis but also the cutaneous appendages opens new perspectives for the treatment of a variety of human skin disorders including severe burns, cutaneous cancers, alopecia and acne. However, the implementation and improvement of
R, Barthel, D, Aberdam
+7 more sources
Frontiers in Bioscience, 2006
Our understanding of adult epidermal stem cells has increased substantially over the last two decades especially; however even more detailed knowledge is imperative for realizing potential medical therapies. We need to know how to identify these cells and what regulates their function.
Angela, Webb, Pritinder, Kaur
openaire +4 more sources
Our understanding of adult epidermal stem cells has increased substantially over the last two decades especially; however even more detailed knowledge is imperative for realizing potential medical therapies. We need to know how to identify these cells and what regulates their function.
Angela, Webb, Pritinder, Kaur
openaire +4 more sources
Dedifferentiation of Epidermal Cells to Stem Cells in Vivo
Lancet, The, 2001The effects of growth factors on wound healing have been studied extensively; however epidermal regeneration is not fully understood. We treated eight patients with leg ulcers with recombinant human epidermal growth factor (rhEGF) and compared biopsies of regenerating epidermis with those of controls who did not receive rhEGF.
Xiaokun Li, Xiaobing Fu, Zhiyong Sheng
exaly +3 more sources
Epidermal stem cells: an update
Current Opinion in Genetics & Development, 2006The mammalian epidermis is a highly accessible tissue in which to study the properties of adult stem cells. Global gene expression profiling has revealed new markers and regulators of the stem cell compartment. Although stem cells have the potential to differentiate into multiple lineages, their progeny follow a more restricted number of lineages in ...
Fiona M, Watt +2 more
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Epidermal Stem Cells in Regenerative Medicine
2020Stem cells present in the epidermis, and hair follicle, guarantee the conservation of adult skin maintenance and hair renewal, but they also play a pivotal role in wound repair and tissue regeneration. Adult stem cells present in the epidermis are also responsible for epidermis different layers' regeneration.We here summarize the epidermal stem cells ...
Martinotti, Simona +3 more
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The multifaceted adult epidermal stem cell
Current Opinion in Cell Biology, 2003Adult epidermal stem cells renew the epithelial compartment of the skin throughout life and are the most accessible of all adult stem cells. Most importantly, epidermal stem cells can be efficiently cultivated and transplanted, a significant advantage for cell and gene therapy.
Gambardella L, Barrandon Y
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Epidermal stem cells in culture
Journal of Cell Science, 1988ABSTRACT Cultures of human epidermal keratinocytes retain many of the characteristics of the tissue from which they are derived, and are therefore useful as an experimental model for studying stem cell properties. The cultures provide evidence that the mechanisms regulating keratinocyte proliferation are complex.
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