Results 261 to 270 of about 5,980,424 (294)

Transcriptional Control of Epidermal Stem Cells

2013
Transcriptional regulation is fundamentally important for the progression of tissue stem cells through different stages of development and differentiation. Mammalian skin epidermis is an excellent model system to study such regulatory mechanisms due to its easy accessibility, stereotypic spatial arrangement, and availability of well-established cell ...
Briana, Lee, Xing, Dai
openaire   +2 more sources

Epidermal Stem Cells

2019
A multilayered epithelium to fulfil its function must be replaced throughout the lifespan. This is possible due to the presence of multipotent, self-renewing epidermal stem cells that give rise to differentiated cell lineages: keratinocytes, hairs, as well as sebocytes.
openaire   +2 more sources

Isolation and Cultivation of Epidermal (Stem) Cells

2018
Recent studies have shown that epidermal stem cells derived from the epidermis of are able to form hair follicles in the presence of hair follicle-inducing cells. Here we describe the method that we have used to isolate and cultivate epidermal stem cells.
Xusheng, Wang, Shiyang, Dong, Yaojiong, Wu   +2 more
openaire   +2 more sources

[Progress in epidermal stem cells].

Yi chuan = Hereditas, 2010
Mammalian skin epidermis contains different epidermal stem cell pools which contribute to the homeostasis and repair of skin epithelium. Epidermal stem cells possess two essential features common to all stem cells: self-renewal and differentiation.
Li-Juan, Wang, You-Liang, Wang, Xiao, Yang   +2 more
openaire   +3 more sources

Contribution of Stem Cells and Differentiated Cells to Epidermal Tumours

Nature Reviews Cancer, 2003
The outer covering of the skin--the epidermis--is subject to sustained environmental assaults. As a result, many cells acquire potentially oncogenic mutations. Most cells are lost through differentiation, and only long-term epidermal residents, such as stem cells, accumulate the number of genetic hits that are necessary for tumour development. So, what
Fiona Watt
exaly   +3 more sources

[Epidermal stem cells].

Bulletin et memoires de l'Academie royale de medecine de Belgique, 2007
info:eu-repo/semantics ...
openaire   +2 more sources

Epidermal Stem Cells and Dermal–Epidermal Junction

2019
Aging of mammalian skin results from two distinct biological processes: intrinsic and extrinsic mechanisms of skin aging. Exposure to solar ultraviolet (UV) radiation (photoaging) is the major extrinsic assault accelerating the normal aging process. The epidermis constitutes the outermost layer of the skin and thus is constantly challenged by harmful ...
Monique Aumailley, Catherin Niemann
openaire   +1 more source

The epidermal stem cell: an overview

Seminars in Developmental Biology, 1993
Abstract The epidermis, the intestinal epithelium and the bone marrow are constantly renewed. Once a terminally differentiated cell has fulfilled its function, it is eliminated. Thus, new differentiated cells need to be constantly produced by the proliferative compartment to ensure the function of the tissue.
openaire   +1 more source

The Contribution of Epidermal Stem Cells to Skin Cancer

Stem Cell Reviews, 2005
Tumors arising from the skin are of multiple phenotypes, with differing degrees of malignant potential. In mouse models of skin carcinogenesis, tumors of squamous phenotype are the most common; however, human disease indicates that multiple phenotypes may arise from a common pool of stem cells that are then influenced by epigenetic factors.
Michael J, Gerdes, Stuart H, Yuspa
openaire   +2 more sources

In Search of the Elusive Epidermal Stem Cell

2006
Recent studies are beginning to reveal that our basic concepts of epidermal stem cell biology may be based on somewhat tenuous ground. For example, it is often assumed that colony-forming cells represent epidermal stem cells, although this has not proved to be the case in hematopoietic cell lineages.
openaire   +2 more sources