Results 61 to 70 of about 22,551 (179)

The complement receptor C5aR2 regulates neutrophil activation and function contributing to neutrophil-driven epidermolysis bullosa acquisita

Frontiers in Immunology, 2023
IntroductionThe function of the second receptor for the complement cleavage product C5a, C5aR2, is poorly understood and often neglected in the immunological context.
Daniel L. Seiler, Katja H. Kähler, Marie Kleingarn, Christian D. Sadik, Christian D. Sadik, Katja Bieber, Katja Bieber, Katja Bieber, Jörg Köhl, Jörg Köhl, Ralf J. Ludwig, Ralf J. Ludwig, Ralf J. Ludwig, Christian M. Karsten   +13 more
doaj   +1 more source

ROS‐Scavenging Multifunctional Microneedle Patch Facilitating Wound Healing

Advanced Healthcare Materials, Volume 14, Issue 31, December 8, 2025.
A reactive oxygen species (ROS) scavenging and immunomodulatory microneedle patch based on hyaluronic acid methacrylate (HaMA) and Flightless I (Flii)‐siRNA‐laden arginine functionalized poly (β‐amino ester)/alginate particles is developed for chronic wound healing applications.
Mahshid Kharaziha, Sahar Salehi, Mahshid Shokri, Seyed Mohsen Ahmadi Tafti, Thomas Scheibel   +4 more
wiley   +1 more source

The Immunometabolomic Interface Receptor Hydroxycarboxylic Acid Receptor 2 Mediates the Therapeutic Effects of Dimethyl Fumarate in Autoantibody-Induced Skin Inflammation

Frontiers in Immunology, 2018
The drug dimethyl fumarate (DMF) is in clinical use for the treatment of psoriasis and multiple sclerosis. In addition, it has recently been demonstrated to ameliorate skin pathology in mouse models of pemphigoid diseases, a group of autoimmune ...
Melanie Wannick, Julian C. Assmann, Jakob F. Vielhauer, Stefan Offermanns, Detlef Zillikens, Christian D. Sadik, Markus Schwaninger   +6 more
doaj   +1 more source

Clinical and immunopathological spectrum of immunoglobulin M pemphigoid: a multicenter case series

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, Volume 23, Issue 12, Page 1555-1564, December 2025.
Summary Background and Objectives Pemphigoid diseases are primarily mediated by IgG or IgA autoantibodies against the cutaneous basement membrane zone (BMZ). Although recent observations suggest the existence of exclusively IgM‐mediated pemphigoid disease, a larger study is lacking.
Kaan Yilmaz, Stephanie Goletz, Christoph M. Hammers, Katharina Boch, Claudia Zeidler, Henning Wiegmann, Estelle Bergmann, Tina Rastegar Lari, Onur Dikmen, Nina Häring, Robert Strohal, Andreas Kleinheinz, Eva N. Hadaschik, Nina van Beek, Sonja Ständer, Enno Schmidt   +15 more
wiley   +1 more source

IgM-mediated epidermolysis bullosa acquisita [PDF]

JAAD Case Reports
Sidney Harrison, BS, Vita Mayes, PA-C, MSc, MPH, MMSc, Conrad Brimhall, MD, Roy King, MD   +3 more
doaj   +2 more sources

Klinisches und immunpathologisches Spektrum des Immunglobulin‐M‐Pemphigoids: eine multizentrische Fallserie

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, Volume 23, Issue 12, Page 1555-1565, December 2025.
Zusammenfassung Hintergrund und Zielsetzung Die Pemphigoid‐Erkrankungen werden primär durch IgG‐ oder IgA‐Autoantikörper gegen die kutane Basalmembranzone (BMZ) vermittelt. Obwohl rezente Arbeiten auf die Existenz einer ausschließlich IgM‐vermittelten Pemphigoid‐Erkrankung hindeuten, fehlt bislang eine umfassendere Untersuchung.
Kaan Yilmaz, Stephanie Goletz, Christoph M. Hammers, Katharina Boch, Claudia Zeidler, Henning Wiegmann, Estelle Bergmann, Tina Rastegar Lari, Onur Dikmen, Nina Häring, Robert Strohal, Andreas Kleinheinz, Eva N. Hadaschik, Nina van Beek, Sonja Ständer, Enno Schmidt   +15 more
wiley   +1 more source

MOESM1 of Reduced Skin Blistering in Experimental Epidermolysis Bullosa Acquisita After Anti-TNF Treatment

, 2018
Reduced Skin Blistering in Experimental Epidermolysis Bullosa Acquisita After Anti-TNF ...
Franziska Schulze (5816831), Marcel Jonkman (5816852), Katja Bieber (4854949), Foteini Beltsiou (5816822), Jennifer Hundt (5816840), Anika Kasprick (4854946), Kathrin Kalies (428737), Hendri Pas (5816846), Ralf Ludwig (1783513), Katharina Dieckhoff (5816825), Unni Samavedam (5816837), Enno Schmidt (314592), Misa Hirose (314585), Detlef Zillikens (314591)   +13 more
core   +1 more source

Therapeutic Effect of a Novel Phosphatidylinositol-3-Kinase δ Inhibitor in Experimental Epidermolysis Bullosa Acquisita

Frontiers in Immunology, 2018
Epidermolysis bullosa acquisita (EBA) is a rare, but prototypical, organ-specific autoimmune disease, characterized and caused by autoantibodies against type VII collagen (COL7).
Hiroshi Koga, Anika Kasprick, Rosa López, Mariona Aulí, Mercè Pont, Núria Godessart, Detlef Zillikens, Katja Bieber, Ralf J. Ludwig, Ralf J. Ludwig, Cristina Balagué   +10 more
doaj   +1 more source

Immunofluorescence testing in the diagnosis of autoimmune blistering diseases: overview of 10-year experience [PDF]

Anais Brasileiros de Dermatologia, 2014
BACKGROUND: Immunofluorescence testing is an important tool for diagnosing blistering diseases. OBJECTIVE: To characterize the immunofluorescence findings in patients diagnosed with autoimmune blistering skin diseases.
Samia Trigo Arbache, Tarsila Gasparotto Nogueira, Lívia Delgado, Denise Miyamoto, Valéria Aoki   +4 more
doaj   +1 more source

Acute renal failure in a patient with epidermolysis bullosa acquisita

, 2017
: Epidermolysis bullosa acquisita is a severe autoimmune subepidermal bullous disease. In this report, we described for the first time a patient with epidermolysis bullosa acquisita who developed acute renal failure.
Qing Yang, Yang,Qing, Zhao,Guowei, Guowei Zhao, Zhang,Furen, Furen Zhang, Zhang, Furen, Zhao, Guowei, Yang, Qing   +8 more
core   +1 more source