Epigallocatechin-3-Gallate, the green tea polyphenol suppresses expression of CD31 and VEGFR2 and enhances the chemotherapeutic potential of irinotecan in AOM/DSS model of colorectal cancer in mice. [PDF]
Rahman SS +4 more
europepmc +1 more source
Epigallocatechin-3-gallate Modulates Hyperglycemia-Triggered Macrophage Autophagy Through miR-204-5p Suppression: Implication for Acute Cardiometabloic Injury. [PDF]
Lin CM +4 more
europepmc +1 more source
Morphological and physicochemical impact of an experimental epigallocatechin-3-gallate based gel on erosive dentin wear. [PDF]
Souza CMS +6 more
europepmc +1 more source
Auxin and Jasmonic Acid Signalling Crosstalk Mediates Plant Growth Regulator-Stimulated Epigallocatechin Gallate Accumulation in Tea Plants (<i>Camellia sinensis</i>). [PDF]
Hu Y +11 more
europepmc +1 more source
Carrier-Free Rapamycin-Loaded Nanoparticles with MRI and Near-Infrared Fluorescence Bimodal Imaging for Precise Diagnosis and Synergistic Therapy of Ischemic Stroke. [PDF]
Yang L +12 more
europepmc +1 more source
Epigallocatechin-3-gallate (EGCG): Chemical and biomedical perspectives [PDF]
The compound (-)-epigallocatechin-3-gallate (EGCG) is the major catechin found in green tea [Camellia sinensis L. Ktze. (Theaceae)]. This polyphenolic compound and several related catechins are believed to be responsible for the health benefits associated with the consumption of green tea.
Dale Nagle
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The Epigenetic Modification of Epigallocatechin Gallate (EGCG) on Cancer
Current Drug Targets, 2020: Among the major components of green tea, epigallocatechin-3-gallate (EGCG) is the most effective for its anti-cancer characteristics. The bulk of studies provide the mechanisms of suppressive function of EGCG are involved in alteration of cancer cell cycle, development, and apoptosis through activation/inhibition of several signal pathways ...
Linqi, Yang +7 more
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Antioxidant and antiviral activities of lipophilic epigallocatechin gallate (EGCG) derivatives
The water soluble green tea polyphenol epigallocatechin gallate (EGCG) was lipophilised by esterification with different fatty acids for expanded applications. Four lipophilic ester derivatives of EGCG, namely EGCG-O-tetrastearate, EGCG-O-tetraeicosapentaenoate, EGCG-O-tetradocosahexaenoate, and EGCG-O-octabutyrate, were prepared and evaluated for ...
Chao-Mei Ma
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Lipophilized Epigallocatechin Gallate (EGCG) Derivatives as Novel Antioxidants
Journal of Agricultural and Food Chemistry, 2011Epigallocatechin gallate (EGCG) is the major polyphenol in green tea and known to render many health benefits associated with tea consumption. EGCG was modified structurally to improve its lipophilicity, expand its application in lipophilic media, and enhance its cellular absorption in vivo.
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