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Dual function of (−)-epigallocatechin gallate (EGCG) in healthy human lymphocytes
Cancer Letters, 2006(-)-Epigallocatechin gallate (EGCG), a catechin polyphenol component, is the main ingredient of green tea extract. Recently, increasing attention has been given to its anti-oxidant effects. However, several studies reported the oxidative effects of EGCG, suggesting that EGCG had a dual function of anti-oxidant and pro-oxidant potentials. In this study,
Masaki, Kanadzu +2 more
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Analysis of the Antimicrobial Activity of Epigallocatechin-3-Gallate (EGCG)
Bulletin of Experimental Biology and MedicineWe studied antimicrobial activity of epigallocatechin-3-gallate (EGCG), a green tea polyphenolic catechin, and its combined use with ceftazidime (CAZ) against bacterial strains of Klebsiella pneumoniae. EGCG exhibited no activity against strains of K. pneumoniae with a different sensitivity to CAZ.
V V, Muravieva +3 more
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Chemoprevention by Epigallocatechin-3-Gallate (EGCG)
2017Tea that is obtained from leaves of the plant Camellia sinensis is subsequent to water and is the most extensively consumed drink in the world. Black, green, and oolong tea are the forms which are produced by the different processing and manufacturing techniques making them chemically different from each other resulting for around 75 %, 23 %, and 2 ...
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Food and Chemical Toxicology, 2006
We have previously demonstrated that 50mg/kg of epigallocatechin gallate (EGCG) is hepatotoxic to female Swiss Webster mice, while lower doses of EGCG and epicatechin gallate (ECG) modulate various cytochrome P450 (CYP) isoforms. Therefore, this study was designed to further investigate the role of strain and sex in catechin-mediated enzyme modulation ...
M G, Goodin, B J, Bray, R J, Rosengren
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We have previously demonstrated that 50mg/kg of epigallocatechin gallate (EGCG) is hepatotoxic to female Swiss Webster mice, while lower doses of EGCG and epicatechin gallate (ECG) modulate various cytochrome P450 (CYP) isoforms. Therefore, this study was designed to further investigate the role of strain and sex in catechin-mediated enzyme modulation ...
M G, Goodin, B J, Bray, R J, Rosengren
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(-)-Epigallocatechin-3-gallate (EGCG) attenuates arsenic-induced cardiotoxicity in rats
Food and Chemical Toxicology, 2016Chronic arsenic exposure in drinking water is associated with the abnormalities of cardiac tissue. Excessive generation of ROS induced by arsenic has a central role in arsenic-induced cardiotoxicity. (-)-Epigallocatechin-3-gallate (EGCG), the most abundant polyphenol in green tea, possesses a potent antioxidant capacity and exhibits extensive ...
Tao-Li, Sun +5 more
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Safety studies on epigallocatechin gallate (EGCG) preparations. Part 1: Genotoxicity
Food and Chemical Toxicology, 2006Public interest in green tea has grown recently due to the potential health benefits from its consumption. Epigallocatechin gallate (EGCG), a principal polyphenolic component of green tea, is considered key to these healthful qualities. Although numerous studies have evaluated the anti-cancer effects of green tea and EGCG, few have examined the safety ...
R A, Isbrucker +3 more
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Research on the Pharmacokinetics and Elimination of Epigallocatechin Gallate (EGCG) in Mice
2013The study was designed to investigate the metabolic kinetics and elimination of Epigallocatechin Gallate (EGCG) in mouse’s tissues, basing on establishing a RP-HPLC method for determination of EGCG in mice plasma, liver, heart, spleen, kidney, pancreas, brain, testis, feces and urine.
Yang Liu +4 more
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Epigallocatechin-3-gallate (EGCG) enhances the therapeutic activity of a dental adhesive
Journal of Dentistry, 2012The purpose of this study was to evaluate the antibacterial potential and physicochemical properties of a dental adhesive incorporated with epigallocatechin-3-gallate (EGCG) in different concentration over time.EGCG was incorporated at a ratio of 100, 200, and 300 μg/ml into a dental adhesive.
Xijin, Du +4 more
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(−)-Epigallocatechin 3-gallate (EGCG) at the ocular surface inhibits corneal neovascularization
Medical Hypotheses, 2011Corneal neovascularization is often accompanied by inflammatory response and loss of their immune privilege which leads to significant visual impairment and worsens the prognosis of a subsequent penetrating keratoplasty. Several types of treatment are currently used. However, there are some associated limitations and complications. The consumption of (-
V, Sánchez-Huerta +2 more
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(−)-Epigallocatechin-3-gallate (EGCG) enhances healing of femoral bone defect
Phytomedicine, 2019Previously, we found that (-)-epigallocatechin-3-gallate (EGCG) enhanced osteogenic differentiation of murine bone marrow mesenchymal stem cells by increasing the mRNA expression of osteogenesis-related genes, alkaline phosphatase activity and eventually mineralization.
Sung-Yen Lin +9 more
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