Results 161 to 170 of about 20,159 (200)

The applications of epigallocatechin gallate (EGCG)-nanogold conjugate in cancer therapy

Nanotechnology, 2023
Abstract Cancer has recently increased the death toll worldwide owing to inadequate therapy and decreased drug bioavailability. Long-term and untargeted chemotherapeutic exposure causes toxicity to healthy cells and drug resistance. These challenges necessitate the development of new methods to increase drug efficacy.
Mehdi Karimi-Shahri, Abbas Alalikhan, Pedram Hashemian, Alireza Hashemzadeh, Hossein Javid   +4 more
openaire   +2 more sources

Biomodification of eroded and abraded dentin with epigallocatechin-3-gallate (EGCG)

Journal of the Mechanical Behavior of Biomedical Materials, 2023
This study aimed to evaluate in vitro the effects of epigallocatechin-3-gallate (EGCG) as a biomodifier of eroded and abraded dentin. Forty dentin specimens were obtained from the buccal surface of bovine teeth. The specimens were randomly distributed in 4 groups according to dentin substrate: sound or eroded/abraded and dentin biomodification: with 0 ...
Bruna Dantas Abreu, Renata Siqueira Scatolin, Silmara Aparecida Milori Corona, Fabiana Almeida Curylofo Zotti   +3 more
openaire   +2 more sources

Acute neurocognitive effects of epigallocatechin gallate (EGCG)

Appetite, 2012
Green tea is reported to have wide ranging beneficial health outcomes across epidemiological studies, which have been attributed to its flavonoid content. We investigated whether the flavonoid epigallocatechin gallate (EGCG) modulates brain activity and self-reported mood in a double-blind, placebo controlled crossover study.
Scholey, Andrew, Downey, Luke, Ciorciari, Joseph, Pipingas, Andrew, Nolidin, Karen, Finn, Melissa, Wines, Melissa, Catchlove, Sarah, Terrens, Alirra, Barlow, Emma, Gordon, Leanne, Stough, Con   +11 more
openaire   +3 more sources

Stability of glycosylated complexes loaded with Epigallocatechin 3-gallate (EGCG)

Food Chemistry, 2023
The application of Epigallocatechin-3-gallate (EGCG) in food industry was limited by its low stability in aqueous solutions and poor bioavailability in vivo. The novel EGCG glycosylated arachin nanoparticles (Ara-CMCS-EGCG) and EGCG glycosylated casein nanoparticles (Cas-CMCS-EGCG) were prepared to improve the stability and bioavailability of EGCG. The
Jianyong, Zhang, Hongchun, Cui, Jiahuan, Qiu, Xiaoqing, Wang, Yixin, Zhong, Caiping, Yao, Lanying, Yao, Qunxiong, Zheng, ChunHua, Xiong   +8 more
openaire   +2 more sources

Encapsulation of (−)-epigallocatechin-gallate (EGCG) in hordein nanoparticles

Food Bioscience, 2020
Abstract (−)-epigallocatechin-gallate (EGCG), a biologically active compound in green tea, has been found to have antimicrobial, anti-carcinogenic, and anti-oxidative activities, but it can easily be degraded when exposed to light and high temperature.
Aijing He, Xiao Guan, Hongdong Song, Sen Li, Kai Huang   +4 more
openaire   +1 more source

Epigallocatechin-3-gallate(EGCG): Mechanisms and the Combined Applications

Combinatorial Chemistry & High Throughput Screening, 2018
EGCG is the most important pharmacological component in tea. Researches have confirmed its effects, including anti-tumor, anti-inflammation, anti-aging, anti-obesity, anti-diabetic, cardiovascular disease prevention and protection, immunoregulation and neuroprotection. Paradoxically, the clinical application of EGCG is very rare.
Xuekun, Song, Juan, Du, Wenyuan, Zhao, Zheng, Guo   +3 more
openaire   +2 more sources

Antiglycation activity of lipophilized epigallocatechin gallate (EGCG) derivatives

Food Chemistry, 2016
Lipophilized EGCG derivatives were synthesized by esterification of EGCG with aliphatic fatty acids and demonstrated to possess many advantages, such as higher lipophilicity and apparent health benefits over the parent EGCG. This study used a total of seven lipophilized EGCG derivatives with fatty acids of different chain lengths attached and examined ...
Mingfu, Wang, Xinchen, Zhang, Ying Joy, Zhong, Nishani, Perera, Fereidoon, Shahidi   +4 more
openaire   +2 more sources

Role of epigallocatechin gallate (EGCG) in the treatment of breast and prostate cancer

Life Sciences, 2006
Green tea and its major constituent epigallocatechin gallate (EGCG) have been extensively studied as a potential treatment for a variety of diseases, including cancer. Epidemiological data have suggested that EGCG may provide protective effects against hormone related cancers, namely breast or prostate cancer.
Emma C, Stuart, Marissa J, Scandlyn, Rhonda J, Rosengren   +2 more
openaire   +2 more sources

Molecular understanding of Epigallocatechin gallate (EGCG) in cardiovascular and metabolic diseases

Journal of Ethnopharmacology, 2018
The compound epigallocatechin-3-gallate (EGCG), the major polyphenolic compound present in green tea [Camellia sinensis (Theaceae], has shown numerous cardiovascular health promoting activity through modulating various pathways. However, molecular understanding of the cardiovascular protective role of EGCG has not been reported.This review aims to ...
Qian Yi, Eng, Punniyakoti Veeraveedu, Thanikachalam, Srinivasan, Ramamurthy   +2 more
openaire   +2 more sources

Anxiolytic properties of green tea polyphenol (−)-epigallocatechin gallate (EGCG)

Brain Research, 2006
Naturally occurring polyphenols are potent antioxidants. Some of these compounds are also ligands for the GABA(A) receptor benzodiazepine site. This feature endows them with sedative properties. Here, the anxiolytic activity of the green tea polyphenol (-)-epigallocatechin gallate (EGCG) was investigated after acute administration in mice, using ...
Vignes, Michel, Maurice, Tangui, Lanté, Fabien, Nedjar, Magali, Thethi, Karen, Guiramand, Janique, Récasens, Max   +6 more
openaire   +3 more sources