Results 181 to 190 of about 14,860 (271)

Chromatin Topology Reconfiguration Orchestrates Thermotolerant Male Fertility via GhAL5 in Cotton

Advanced Science, EarlyView.
This study investigates cotton’s high‐temperature (HT) response using multi‑omics. Dynamic 3D genome changes drive expression bias affecting male fertility. The tolerant line shows controlled chromatin dynamics, while the sensitive line exhibits overactivation.
Yanlong Li, Jing Yang, Weiran Wang, Chunyang Zuo, Liuling Pei, Yizan Ma, Rui Zhang, Yaru Fan, Huanhuan Ma, Yawei Li, Ruizhen Liu, Shuangxia Jin, Longfu Zhu, Jie Kong, Xianlong Zhang, Ling Min   +15 more
wiley   +1 more source

Characterising developmental dynamics of adult epigenetic clock sites. [PDF]

EBioMedicine
Mulder RH, Neumann A, Felix JF, Suderman M, Cecil CAM.   +4 more
europepmc   +1 more source

Epigenetic clock and methylation studies in vervet monkeys. [PDF]

Geroscience, 2022
Jasinska AJ, Haghani A, Zoller JA, Li CZ, Arneson A, Ernst J, Kavanagh K, Jorgensen MJ, Mattison JA, Wojta K, Choi OW, DeYoung J, Li X, Rao AW, Coppola G, Freimer NB, Woods RP, Horvath S.   +17 more
europepmc   +1 more source

Ribosome Homeostasis Regulated by SETD2 Preserves Intestinal Epithelial Barrier

Advanced Science, EarlyView.
SETD2 ablation causes dysregulation and recruitment defects of ribosome biogenesis factors, resulting in translational disorders of barrier maintenance genes, thereby compromising the intestinal barrier. These findings unveil a previously unappreciated role of ribosome biogenesis and translational regulation in preserving the intestinal epithelial ...
Hanyu Rao, Aiting Wang, Yue Xu, Wenxin Feng, Chunxiao Ma, Ziyi Wang, Wei Zhang, Wenqiong Su, Xiuying Xiao, Wei‐Qiang Gao, Xianting Ding, Li Li   +11 more
wiley   +1 more source

Epigenetic Clock Analysis for National Institutes of Health Stroke Scale in Patients With Ischemic Stroke. [PDF]

Neuropsychopharmacol Rep
Jiang W, Shirai T, Otsuka I, Okazaki S, Tanifuji T, Horai T, Minami H, Miyachi M, Okada S, Hishimoto A.   +9 more
europepmc   +1 more source

Epigenetic clock and methylation studies in the rhesus macaque. [PDF]

Geroscience, 2021
Horvath S, Zoller JA, Haghani A, Jasinska AJ, Raj K, Breeze CE, Ernst J, Vaughan KL, Mattison JA.   +8 more
europepmc   +1 more source

Additional file 2: of The epigenetic clock as a predictor of disease and mortality risk: a systematic review and meta-analysis

, 2019
Peter Fransquet, Jo Wrigglesworth, Robyn L. Woods, Michael E. Ernst, Joanne Ryan   +4 more
openalex   +1 more source

Tendon Organoids Enable Functional Tendon Rejuvenation Through ALKBH5‐Dependent RNA Demethylation

Advanced Science, EarlyView.
FT organoids reverse the aged phenotype of tendon cells, reinstating a fetal‐like state. This breakthrough establishes a potent cell source for tendon tissue engineering, effectively advancing regenerative medicine. ABSTRACT Adult tendon injuries pose a major clinical challenge due to limited self‐repair capacity, resulting in suboptimal regeneration ...
Tian Qin, Aini Pan, Zhuoning Miao, Yanyan Zhao, Xianan Mo, Heng Sun, Chunmei Fan, Junyu Guo, Bingbing Wu, Weiliang Shen, Qiangqiang Zheng, Jun Lu, Xi Jiang, Zi Yin, Xiao Chen   +14 more
wiley   +1 more source

Epigenetic Clock in Bears: A Simple Cost-Effective Blood DNA Methylation-Based Age Estimation Method Applicable to Multiple Bear Species. [PDF]

Ecol Evol
Shimozuru M, Nakamura S, Yamazaki J, Yanagawa Y, Tamatani H, Kuroe M, Yamazaki K, Koike S, Goto Y, Naganuma T, Tochigi K, Inagaki A, Takekoshi N, Baek S, Sato N, Honda Y, Tsubota T, Ito H.   +17 more
europepmc   +1 more source

Epigenetic clock indicates accelerated aging in glial cells of progressive multiple sclerosis patients. [PDF]

Front Aging Neurosci, 2022
Kular L, Klose D, Urdánoz-Casado A, Ewing E, Planell N, Gomez-Cabrero D, Needhamsen M, Jagodic M.   +7 more
europepmc   +1 more source