, 2013 Epigenetic Tracking (ET) is an Artificial Embryology system which allows for the evolution and development of large complex structures built from artificial cells.
Fontana, Alessandro, Wróbel, Borys
core +2 more sources
GrimAge Outperforms Other Epigenetic Clocks in the Prediction of Age-Related Clinical Phenotypes and All-Cause Mortality [PDF]
, 2020 Cathal McCrory +10 more
openalex +1 more source
Whole‐Blood RNA Sequencing Profiling of Patients With Rheumatoid Arthritis Treated With Tofacitinib
ACR Open Rheumatology, EarlyView.Objective Patients with rheumatoid arthritis (RA) often fail to respond to therapies, including JAK inhibitors (JAKi), and treatment allocation is made via a trial‐and‐error strategy. A comprehensive analysis of responses to JAKi, including tofacitinib, by RNA sequencing (RNAseq) would allow the discovery of transcriptomic markers with a two‐fold ...
Chiara Bellocchi +11 more
wiley +1 more source
Underlying features of epigenetic aging clocks in vivo and in vitro [PDF]
, 2020 Zuyun Liu +9 more
openalex +1 more source
A New Monocyte Epigenetic Clock Reveals Effects of Alcohol Consumption on Epigenetic Aging in Three Independent Cohorts [PDF]
, 2021 Xiaoyu Liang +5 more
openalex +1 more source
Advanced Biology, EarlyView.Chromatin, which organizes DNA, changes its structure to adapt to stress like high oxygen levels (hyperoxia), which can damage cells. Researchers developed a technique to observe these changes and found variability in how different parts of chromatin remodel.
Lauren Monroe +4 more
wiley +1 more source
Desynchronization of Circadian Clocks in Cancer: A Metabolic and Epigenetic Connection [PDF]
, 2017 Kiran Padmanabhan, Marc Billaud
openalex +1 more source
Association of 4 epigenetic clocks with measures of functional health, cognition, and all-cause mortality in The Irish Longitudinal Study on Ageing (TILDA) [PDF]
, 2020 Cathal McCrory +10 more
openalex +1 more source
Systems aging clock: A novel epigenetic aging clock modeled from organ & bodily function based mortality indices [PDF]
, 2021 Raghav Sehgal, Morgan E. Levine
openalex +1 more source