Results 131 to 140 of about 307,044 (299)

Poster 113: Epigenetic Regulation of PPARγ Rescues Articular Chondrocytes from Catabolic State Suggesting PPARγ as a Potential Target to Slow Down Progression of OA in Hip FAI [PDF]

, 2023
Tomoyuki Kamenaga, Jie Shen, May Wu, Robert H. Brophy, Regis J. O’Keefe, John C. Clohisy, Cecilia Pascual‐Garrido   +6 more
openalex   +1 more source

Kidney Organoids in Drug Development: Integrating Technological Advances and Standardization for Effective Implementation

Advanced Healthcare Materials, EarlyView.
This review examines how emerging enabling technologies enhance the physiological relevance, scalability, and reproducibility of kidney organoids, while advanced analytical approaches support model validation and deepen mechanistic insight into nephrotoxicity.
Helen Kearney, Silvia M. Mihăilă, Lorenzo Moroni, Carlos Mota   +3 more
wiley   +1 more source

Rapid profiling of transcription factor-cofactor interaction networks reveals principles of epigenetic regulation [PDF]

Melissa M Inge, R. G. Miller, Heather Hook, David A. Bray, JL Keenan, Rong Zhao, Thomas D. Gilmore, Trevor Siggers   +7 more
openalex   +1 more source

Reviewer #2 (Public Review): Plasma Growth Hormone Pulses Induce Male-biased Pulsatile Chromatin Opening and Epigenetic Regulation in Adult Mouse Liver

, 2023
Andy Rampersaud, Jeannette Connerney, David J. Waxman   +2 more
openalex   +1 more source

Evaluation of the Dual Impact of Nanotechnologies on Health and Environment Through Alternative Bridging Models

Advanced Healthcare Materials, EarlyView.
This review explores how alternative invertebrate and small‐vertebrate models advance the evaluation of nanomaterials across medicine and environmental science. By bridging cellular and organismal levels, these models enable integrated assessment of toxicity, biodistribution, and therapeutic performance.
Marie Celine Lefevre, Margherita Bernardeschi, Matteo Battaglini, Gianni Ciofani   +3 more
wiley   +1 more source

Dietary Sulforaphane in Cancer Chemoprevention: The Role of Epigenetic Regulation and HDAC Inhibition

, 2014
Stephanie M. Tortorella, Simon G. Royce, Paul V. Licciardi, Tom C. Karagiannis   +3 more
openalex   +1 more source

Epigenetic Regulation Associated With Sirtuin 1 in Complications of Diabetes Mellitus [PDF]

, 2021
Jie Wang, Shudong Wang, Jie Wang, Mengjie Xiao, Yuanfang Guo, Yufeng Tang, Jingjing Zhang, Junlian Gu   +7 more
openalex   +1 more source

Matrix Stiffness Governs Fibroblasts’ Regulation of Gingival Immune Homeostasis

Advanced Materials, EarlyView.
This study identifies a “mechano‐epigenetic” checkpoint in which matrix stiffness governs the immune responses of gingival fibroblasts. Using biomimetic hydrogels and human gingival explants, the studies revealed that restoring extracellular matrix stiffness actively suppresses inflammation via non‐canonical NF‐κB signaling and DNA methylation ...
Hardik Makkar, Nghi Tran, Yu‐Chang Chen, Kang I. Ko, Rebecca G. Wells, Kyle H. Vining   +5 more
wiley   +1 more source

Epigenetic regulation of transcription in intermediate heterochromatin [PDF]

, 2006
Yoshiki Habu, Olivier Mathieu, Muhammad Tariq, Aline V. Probst, Chotika Smathajitt, Tong Zhu, Jerzy Paszkowski   +6 more
openalex   +1 more source

Microenvironment Modulation‐Based Nanomaterial‐Loaded Hydrogel Dressings for Diabetic Foot Ulcers: Research Progress and Future Perspectives

Advanced Materials Interfaces, EarlyView.
xx xx. ABSTRACT Diabetic foot ulcer (DFU) is a chronic complication of diabetes, primarily caused by hyperglycemia, peripheral vascular disease, and neuropathy. Characterized by persistent hyperglycemia, impaired perfusion, inflammation, and infection, DFUs pose significant challenges to healing and are associated with high morbidity and amputation ...
Tang Yuqing, Chen Hong, Fan Weijing, Huang Renyan, You Yang, Liu Guobin   +5 more
wiley   +1 more source