Results 61 to 70 of about 495,214 (384)

The Many Faces of EpigeneticsOxford, December 2017

open access: yesEpigenetics, 2019
The conference ‘The Many Faces of Epigenetics: Multidisciplinary Perspectives “over” Genetics’ was held in Oxford (6–8 December 2017) and offered a valuable window into the domain of Epigenetics and its promises.
Paola B. Arimondo   +2 more
doaj   +1 more source

The social construction of the social epigenome and the larger biological context

open access: yesEpigenetics & Chromatin, 2020
Epigenetics researchers in developmental, cell, and molecular biology greatly diverge in their understanding and definitions of epigenetics. In contrast, social epigeneticists, e.g., sociologists, scholars of STS, and behavioural scientists, share a ...
Ute Deichmann
doaj   +1 more source

The Mbd1-Atf7ip-Setdb1 pathway contributes to the maintenance of X chromosome inactivation. [PDF]

open access: yes, 2014
BackgroundX chromosome inactivation (XCI) is a developmental program of heterochromatin formation that initiates during early female mammalian embryonic development and is maintained through a lifetime of cell divisions in somatic cells.
Bonora, Giancarlo   +5 more
core   +3 more sources

Hematopoietic (stem) cells—The elixir of life?

open access: yesFEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo   +4 more
wiley   +1 more source

Epigenetics as a first exit problem

open access: yes, 2001
We develop a framework to discuss stability of epigenetic states as first exit problems in dynamical systems with noise. We consider in particular the stability of the lysogenic state of the lambda prophage, which is known to exhibit exceptionally large ...
Aurell, E., Sneppen, K.
core   +1 more source

From early stress to 12-month development in very preterm infants: Preliminary findings on epigenetic mechanisms and brain growth [PDF]

open access: yes, 2018
Very preterm (VPT) infants admitted to Neonatal Intensive Care Unit (NICU) are at risk for altered brain growth and less-than-optimal socio-emotional development.
Borgatti, R.   +13 more
core   +1 more source

Molecular bases of circadian magnesium rhythms across eukaryotes

open access: yesFEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Matrix stiffness aggravates osteoarthritis progression through H3K27me3 demethylation induced by mitochondrial damage

open access: yesiScience
Summary: Abnormal epigenetics is the initial factor of the occurrence and development of osteoarthritis (OA), and abnormal mechanical load is a key pathogenic factor of OA. However, how abnormal mechanical load affects chondrocyte epigenetics is unclear.
Tianyou Kan   +8 more
doaj   +1 more source

Maternal SMCHD1 regulates Hox gene expression and patterning in the mouse embryo

open access: yesNature Communications, 2022
Parents transmit both genetic and epigenetic information to their offspring, with maternal effect genes being critical regulators of the offspring epigenome.
Natalia Benetti   +7 more
doaj   +1 more source

Environmental Epigenetics [PDF]

open access: yesEnvironmental Epigenetics, 2015
With over 350 journals, Oxford University Press is one of the largest publishers of scientific journals. In considering their portfolio recently, they realized they had no specific journals in the rapidly growing area of epigenetics. When they approached me about helping to establish a journal in this area, I considered what other journals had been ...
openaire   +3 more sources

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