Results 61 to 70 of about 369,301 (351)
The Many Faces of EpigeneticsOxford, December 2017
Epigenetics, 2019 The conference ‘The Many Faces of Epigenetics: Multidisciplinary Perspectives “over” Genetics’ was held in Oxford (6–8 December 2017) and offered a valuable window into the domain of Epigenetics and its promises.
Paola B. Arimondo +2 more
doaj +1 more source
PLoS Biology, 2010 Imagine—you’ve just been born, and your future looks bleak. After an all-too brief infancy when you’ll be cared for and fed, you’ll be forced into child labour, cleaning a dark and crowded home and caring for your many siblings. You’ll be subsequently put on guard duty to defend your home against vicious intruders. If you survive, you’ll spend the rest
Chittka, A, Chittka, L
openaire +6 more sources
Autophagy in cancer and protein conformational disorders
FEBS Letters, EarlyView.Autophagy plays a crucial role in numerous biological processes, including protein and organelle quality control, development, immunity, and metabolism. Hence, dysregulation or mutations in autophagy‐related genes have been implicated in a wide range of human diseases.
Sergio Attanasio
wiley +1 more source
Will epigenetics ever be a biosocial science? A reply to Chiapperino and Paneni
Epigenetics Communications, 2023 The recent correspondence article by Chiapperino and Paneni in Clinical Epigenetics correctly points to the inability of epigenetics to incorporate fine-grained mapping data of the individual’s surrounding milieu.
Silvio Zaina
doaj +1 more source
The Impact of Nutrition and Environmental Epigenetics on Human Health and Disease
International Journal of Molecular Sciences, 2018 Environmental epigenetics describes how environmental factors affect cellular epigenetics and, hence, human health. Epigenetic marks alter the spatial conformation of chromatin to regulate gene expression.
C. Tiffon
semanticscholar +1 more source
The danger of epigenetics misconceptions (epigenetics and stuff…) [PDF]
Biochemistry and Cell Biology, 2015 Within the past two decades, the fields of chromatin structure and function and transcription regulation research started to fuse and overlap, as evidence mounted to support a very strong regulatory role in gene expression that was associated with histone post-translational modifications, DNA methylation, as well as various chromatin-associated ...
openaire +3 more sources
FEBS Letters, EarlyView.The protonated form of butyrate, as well as other short‐chain fatty acids (SCFAs), is membrane permeable. In acidic extracellular environments, this can lead to intracellular accumulation of SCFAs and cytosolic acidification. This phenomenon will be particularly relevant in acidic environments such as the large intestine or tumor microenvironments ...
Muwei Jiang +2 more
wiley +1 more source
TAZ2 truncation confers overactivation of p300 and cellular vulnerability to HDAC inhibition
Nature Communications, 2023 The histone acetyltransferase p300/CBP is composed of several conserved domains, among which, the TAZ2 domain is known as a protein-protein interaction domain that binds to E1A and various transcription factors.
Longxia Xu +8 more
doaj +1 more source
The physics of epigenetics [PDF]
Reviews of Modern Physics, 2016 In higher organisms, all cells share the same genome, but every cell expresses only a limited and specific set of genes that defines the cell type. During cell division, not only the genome, but also the cell type is inherited by the daughter cells.
Cortini, Ruggero +6 more
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Evolutionary interplay between viruses and R‐loops
FEBS Letters, EarlyView.Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi +4 more
wiley +1 more source