Results 51 to 60 of about 150,500 (308)
Maternal SMCHD1 regulates Hox gene expression and patterning in the mouse embryo
Nature Communications, 2022 Parents transmit both genetic and epigenetic information to their offspring, with maternal effect genes being critical regulators of the offspring epigenome.
Natalia Benetti +7 more
doaj +1 more source
Epigenetic engineering and the art of epigenetic manipulation [PDF]
Genome Biology, 2014 AbstractA report on the Epigenetic Engineering Meeting hosted by the Barts Institute of Cancer, held in London, UK, May 7 ...
openaire +3 more sources
Computational Methods in Epigenetics
, 2015 Epigenetics is the study of heritable changes in gene expression resulting from modifications in chromatin structure, without involving changes in the genetic information stored in DNA.
Jose M. Eirin-Lopez +9 more
core +1 more source
The human gut microbiome across the life course
FEBS Letters, EarlyView.Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Will epigenetics ever be a biosocial science? A reply to Chiapperino and Paneni
Epigenetics Communications, 2023 The recent correspondence article by Chiapperino and Paneni in Clinical Epigenetics correctly points to the inability of epigenetics to incorporate fine-grained mapping data of the individual’s surrounding milieu.
Silvio Zaina
doaj +1 more source
The danger of epigenetics misconceptions (epigenetics and stuff…) [PDF]
Biochemistry and Cell Biology, 2015 Within the past two decades, the fields of chromatin structure and function and transcription regulation research started to fuse and overlap, as evidence mounted to support a very strong regulatory role in gene expression that was associated with histone post-translational modifications, DNA methylation, as well as various chromatin-associated ...
openaire +3 more sources
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Complete loss of H3K9 methylation dissolves mouse heterochromatin organization
Nature Communications, 2021 Histone H3K9 methylation (H3K9me) states define repressed chromatin in eukaryotic cells. Here the authors reveal complete loss of all H3K9me in mammalian cells through successive deletion of H3K9 methyltransferase genes that results in the dissolution of
Thomas Montavon +10 more
doaj +1 more source
Genes, 2019 This special issue of Genes demonstrates clearly that research in epigenetics has proceeded at a very rapid pace in the last decade [...]
Christoph Grunau +3 more
openaire +4 more sources