Results 51 to 60 of about 153,638 (306)

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

Matrix stiffness aggravates osteoarthritis progression through H3K27me3 demethylation induced by mitochondrial damage

open access: yesiScience
Summary: Abnormal epigenetics is the initial factor of the occurrence and development of osteoarthritis (OA), and abnormal mechanical load is a key pathogenic factor of OA. However, how abnormal mechanical load affects chondrocyte epigenetics is unclear.
Tianyou Kan   +8 more
doaj   +1 more source

Maternal SMCHD1 regulates Hox gene expression and patterning in the mouse embryo

open access: yesNature Communications, 2022
Parents transmit both genetic and epigenetic information to their offspring, with maternal effect genes being critical regulators of the offspring epigenome.
Natalia Benetti   +7 more
doaj   +1 more source

Computational Methods in Epigenetics

open access: yes, 2015
Epigenetics is the study of heritable changes in gene expression resulting from modifications in chromatin structure, without involving changes in the genetic information stored in DNA.
Jose M. Eirin-Lopez   +9 more
core   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Will epigenetics ever be a biosocial science? A reply to Chiapperino and Paneni

open access: yesEpigenetics Communications, 2023
The recent correspondence article by Chiapperino and Paneni in Clinical Epigenetics correctly points to the inability of epigenetics to incorporate fine-grained mapping data of the individual’s surrounding milieu.
Silvio Zaina
doaj   +1 more source

Epigenetics Approaches toward Precision Medicine for Idiopathic Pulmonary Fibrosis: Focus on DNA Methylation

open access: yesBiomedicines, 2023
Genetic information is not transmitted solely by DNA but by the epigenetics process. Epigenetics describes molecular missing link pathways that could bridge the gap between the genetic background and environmental risk factors that contribute to the ...
Wiwin Is Effendi, Tatsuya Nagano
doaj   +1 more source

bgruening/docker-galaxy-epigenetics: 17.09 release

open access: yes, 2017
:whale::bar_chart::books: Docker Images for epigenetics data ...
Joachim Wolff, Björn Grüning
core   +1 more source

Epigenetic engineering and the art of epigenetic manipulation [PDF]

open access: yesGenome Biology, 2014
AbstractA report on the Epigenetic Engineering Meeting hosted by the Barts Institute of Cancer, held in London, UK, May 7 ...
openaire   +3 more sources

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

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