Results 41 to 50 of about 224,057 (304)
Maternal nutritional status, C1 metabolism and offspring DNA methylation: a review of current evidence in human subjects. [PDF]
, 2011 : Evidence is growing for the long-term effects of environmental factors during early-life on later disease susceptibility. It is believed that epigenetic mechanisms (changes in gene function not mediated by DNA sequence alteration), particularly DNA ...
Cox, SE +4 more
core +4 more sources
Crossovers between epigenesis and epigenetics. A multicenter approach to the history of epigenetics (1901-1975) [PDF]
, 2014 The origin of epigenetics has been traditionally traced back to Conrad Hal Waddington's foundational work in 1940s. The aim of the present paper is to reveal a hidden history of epigenetics, by means of a multicenter approach.
Costa, R., Frezza, G.
core
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
The social construction of the social epigenome and the larger biological context
Epigenetics & Chromatin, 2020 Epigenetics researchers in developmental, cell, and molecular biology greatly diverge in their understanding and definitions of epigenetics. In contrast, social epigeneticists, e.g., sociologists, scholars of STS, and behavioural scientists, share a ...
Ute Deichmann
doaj +1 more source
Epigenetic regulation of adaptive responses of forest tree species to the environment [PDF]
, 2013 Epigenetic variation is likely to contribute to the phenotypic plasticity and adaptative capacity of plant species, and may be especially important for long-lived organisms with complex life cycles, including forest trees.
Bräutigam, Katharina +16 more
core +3 more sources
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
iScienceSummary: Abnormal epigenetics is the initial factor of the occurrence and development of osteoarthritis (OA), and abnormal mechanical load is a key pathogenic factor of OA. However, how abnormal mechanical load affects chondrocyte epigenetics is unclear.
Tianyou Kan +8 more
doaj +1 more source
Maternal SMCHD1 regulates Hox gene expression and patterning in the mouse embryo
Nature Communications, 2022 Parents transmit both genetic and epigenetic information to their offspring, with maternal effect genes being critical regulators of the offspring epigenome.
Natalia Benetti +7 more
doaj +1 more source
Environmental Epigenetics [PDF]
Environmental Epigenetics, 2015 With over 350 journals, Oxford University Press is one of the largest publishers of scientific journals. In considering their portfolio recently, they realized they had no specific journals in the rapidly growing area of epigenetics. When they approached me about helping to establish a journal in this area, I considered what other journals had been ...
openaire +3 more sources
Methylmercury Epigenetics [PDF]
Toxics, 2019 Methylmercury (MeHg) has conventionally been investigated for effects on nervous system development. As such, epigenetic modifications have become an attractive mechanistic target, and research on MeHg and epigenetics has rapidly expanded in the past decade.
Megan Culbreth, Michael Aschner
openaire +3 more sources