Results 41 to 50 of about 150,500 (308)

Epigenetics of infectious diseases

open access: yes, 2021
Infectious diseases are a leading cause of human morbidity and mortality worldwide, and they are caused by a variety of pathogenic bacteria, viruses, parasites, and fungi.
M.P. Jennings   +3 more
core   +1 more source

The Many Faces of EpigeneticsOxford, December 2017

open access: yesEpigenetics, 2019
The conference ‘The Many Faces of Epigenetics: Multidisciplinary Perspectives “over” Genetics’ was held in Oxford (6–8 December 2017) and offered a valuable window into the domain of Epigenetics and its promises.
Paola B. Arimondo   +2 more
doaj   +1 more source

Construction of a Review About Epigenetics for Biology Teachers and Other Non-experts

open access: yes, 2021
Epigenetics, the new research field at the cutting edge of biology research, needs to be introduced in biology education. The aim of this review is to support biology teachers and other non-experts to get an overview of the field, as a review in ...
Mc Ewen, Birgitta,, Mc Ewen, Birgitta
core   +1 more source

Ethical implications of epigenetics in the era of personalized medicine [PDF]

open access: yes, 2022
Given the increasing research activity on epigenetics to monitor human diseases and its connection with lifestyle and environmental expositions, the field of epigenetics has attracted a great deal of interest also at the ethical and societal level.
Santaló, Josep   +2 more
core   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Why epigenetics is (not) a biosocial science and why that matters

open access: yes, 2022
Epigenetic modifications offer compelling evidence of the environmental etiology of complex diseases. Social and biographical conditions, as well as material exposures, all modulate our biology with consequences for risk predispositions and health ...
Chiapperino, Luca, Francesco, Paneni
core   +1 more source

Epigenetics, chromatin and brain development and function

open access: yesBrain and Neuroscience Advances, 2018
Research investigating epigenetics and chromatin function in brain and behaviour has mushroomed over the last two decades. And yet epigenetics as a biological concept predates the discovery in the 1950s of DNA as the principle mode of inheritance by over
Anthony R. Isles
doaj   +1 more source

The social construction of the social epigenome and the larger biological context

open access: yesEpigenetics & Chromatin, 2020
Epigenetics researchers in developmental, cell, and molecular biology greatly diverge in their understanding and definitions of epigenetics. In contrast, social epigeneticists, e.g., sociologists, scholars of STS, and behavioural scientists, share a ...
Ute Deichmann
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Matrix stiffness aggravates osteoarthritis progression through H3K27me3 demethylation induced by mitochondrial damage

open access: yesiScience
Summary: Abnormal epigenetics is the initial factor of the occurrence and development of osteoarthritis (OA), and abnormal mechanical load is a key pathogenic factor of OA. However, how abnormal mechanical load affects chondrocyte epigenetics is unclear.
Tianyou Kan   +8 more
doaj   +1 more source

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