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The field of Epigenetics represents the science which helps us understand the influence life has on genetic function. Research has shown that what we do, what we are exposed to, and the internal and external environments have significant influence on the output of our genes. In this article, the reader will understand how alterations in the DNA explain
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Objectives: Recent evidence from the fields of microbiology and immunology, as well as a small number of human sepsis studies, suggest that epigenetic regulation may play a central role in the pathogenesis of sepsis. The term “epigenetics” refers to regulatory mechanisms that control gene expression but are not related to ...
Binnie, Alexandra +5 more
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Epigenetics and Lifestyle [PDF]
The concept of 'lifestyle' includes different factors such as nutrition, behavior, stress, physical activity, working habits, smoking and alcohol consumption. Increasing evidence shows that environmental and lifestyle factors may influence epigenetic mechanisms, such as DNA methylation, histone acetylation and miRNA expression.
J. A. Alegría Torres +2 more
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Epigenetics of Aging and Aging-Associated Diseases
Aging represents the multifactorial decline in physiological function of every living organism. Over the past decades, several hallmarks of aging have been defined, including epigenetic deregulation.
D. Saul, R. Kosinsky
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The Epigenetic Cytocrin Pathway to the Nucleus. Epigenetic Factors, Epigenetic Mediators, and Epigenetic Traits. A Biochemist Perspective [PDF]
A single word, Epigenetics, underlies one exciting subject in today's Science, with different sides and with interactions with philosophy. The apparent trivial description includes everything in between genotype and phenotype that occurs for a given unique DNA sequence/genome.
Gemma Navarro +5 more
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Epigenetic Regulation and Measurement of Epigenetic Changes [PDF]
Epigenetic mechanisms provide an adaptive layer of control in the regulation of gene expression that enables an organism to adjust to a changing environment. Epigenetic regulation increases the functional complexity of deoxyribonucleic acid (DNA) by altering chromatin structure, nuclear organization, and transcript stability.
Stephens, Kimberly E +4 more
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Lowly methylated region analysis identifies EBF1 as a potential epigenetic modifier in breast cancer
Breast cancer (BC) encompasses heterogeneous pathologies with different subtypes exhibiting distinct molecular changes, including those related to DNA methylation.
Nora Fernandez-Jimenez +9 more
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Epigenetics for Crop Improvement in Times of Global Change
Simple Summary Research on plant epigenetics aims to understand how endogenous, biotic, and abiotic factors regulate plant development and growth independent of changes in the genome sequence.
I. Kakoulidou +12 more
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Epigenetics in the pathogenesis of diabetic nephropathy
Diabetic nephropathy (DN), which is a common microvascular complication with a high incidence in diabetic patients, greatly increases the mortality of patients.
Xue Li +7 more
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Modern Epigenetics Methods in Biological Research
The definition of epigenetics refers that molecular modifications on DNA that can regulate gene activity are independent of DNA sequence and mitotically stable. Notably, epigenetics studies have grown exponentially in the past few years.
Yuanyuan Li
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