Results 31 to 40 of about 150,500 (308)

Environmentally Induced Epigenetic Plasticity in Development: Epigenetic Toxicity and Epigenetic Adaptation [PDF]

open access: yesCurrent Epidemiology Reports, 2018
Epigenetic processes represent important mechanisms underlying developmental plasticity in response to environmental exposures. The current review discusses three classes of environmentally-induced epigenetic changes reflecting two aspects of that plasticity, toxicity effects as well as adaptation in the process of development.Due to innate resilience,
Fu-Ying, Tian, Carmen J, Marsit
openaire   +2 more sources

Environmental Epigenetics update [PDF]

open access: yes, 2018
The journal Environmental Epigenetics, published by Oxford University Press, was founded in 2015 and its first issue published the fall of that year. Since then we have continuously published four issues per year and the journal has grown.
Michael K Skinner, Skinner, Michael K
core   +1 more source

Epigenetics Regulates Antitumor Immunity in Melanoma

open access: yesFrontiers in Immunology, 2022
Melanoma is the most malignant skin cancer, which originates from epidermal melanocytes, with increasing worldwide incidence. The escape of immune surveillance is a hallmark of the tumor, which is manifested by the imbalance between the enhanced immune ...
Yuhan Chen   +6 more
doaj   +1 more source

Epigenetics and Psychiatry [PDF]

open access: yesNeurotherapeutics, 2013
Psychiatric disorders including major depressive disorder, drug addiction, and schizophrenia are debilitating illnesses with a multitude of complex symptoms underlying each of these disorders. In recent years, it has become appreciated that the onset and development of these disorders goes beyond the one gene-one disease approach.
Melissa, Mahgoub, Lisa M, Monteggia
openaire   +2 more sources

Comprehensive evaluation of genome-wide 5-hydroxymethylcytosine profiling approaches in human DNA

open access: yesEpigenetics & Chromatin, 2017
Background The discovery that 5-methylcytosine (5mC) can be oxidized to 5-hydroxymethylcytosine (5hmC) by the ten-eleven translocation (TET) proteins has prompted wide interest in the potential role of 5hmC in reshaping the mammalian DNA methylation ...
Ksenia Skvortsova   +6 more
doaj   +1 more source

“Epic-Genetics”: An exploration of preservice helping professionals’ (mis)understanding of epigenetic influences on human development

open access: yesTeaching & Learning Inquiry: The ISSOTL Journal, 2020
Mental health researchers emphasize the importance of practitioner understanding of biology-environment interplay. Accordingly, our goal of the study described in this article was to understand students’ preconceptions and misconceptions about biological
Kate E. Snyder   +3 more
doaj   +1 more source

Epigenetic reprogramming at estrogen-receptor binding sites alters 3D chromatin landscape in endocrine-resistant breast cancer

open access: yesNature Communications, 2020
Endocrine therapy resistance occurs often in estrogen receptor positive (ER+) breast cancer. Here, the authors find that 3D epigenome remodelling at ER-bound enhancer-promoter interactions is a key mechanism underlying endocrine resistance.
Joanna Achinger-Kawecka   +18 more
doaj   +1 more source

Epigenetics and Obesity

open access: yes, 2022
Obesity is an important health problem that has reached the level of pandemic today, has important effects on high prevalence diseases such as cardiovascular, diabetes, and cancer, and even leads to deaths. Obesity occurs from multifactorial effects,
Sarac, Handan
core   +1 more source

Replication timing and epigenome remodelling are associated with the nature of chromosomal rearrangements in cancer

open access: yesNature Communications, 2019
The connection between DNA replication timing and changes that occur to the epigenome in cancer are still poorly understood. Here, the authors perform Repli-Seq and integrated epigenome analyses and find that genomic regions that undergo long-range ...
Qian Du   +13 more
doaj   +1 more source

Chromatin and Epigenetics [PDF]

open access: yesPlant Physiology, 2015
Wrapping DNA around protein beads, to form so-called nucleosomes, is an ingenious invention of nature allowing the condensation of an enormous amount of genomic information into a tiny package.
Anna, Amtmann, Hong, Ma, Doris, Wagner
openaire   +2 more sources

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